A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy

Ahmet  Bilici; Mesut  Şeker; Başak Bala Ustaalioğlu  Öven; Tarık  Salman; Taflan  Salepçi; Dilek  Yavuzer; Mahmut  Gümüş

Anastrazol Tedavisi Altında İzole Över Metastazı ile Saptanan Nüks Meme Kanseri Olgusu

Year 2010, Volume: 43 Issue: 1, 42 - 45, 01.04.2010

Ahmet Bilici Mesut Şeker Başak Bala Ustaalioğlu Öven Tarık Salman Taflan Salepçi Dilek Yavuzer Mahmut Gümüş

Abstract

Ovarian metastases originate from mostly genital organ, aftervvards gastrointestinal tract and breast carcinoma, respectively. İn this report, we present a case of recurrent breast cancer who vvas diagnosed vvith isolated ovarian metastases seven years after the diagnosis of breast cancer and had treated vvith adjuvant chemotherapy and vvere followed-up under anastrozole treatment. She vvas presented vvith abdominal pain at the right lovver side. Radiological examinations revealed a mass vvhich vvas similar to uterine leiomyoma in the uterus. A total hysterectomy vvith bilateral salpingo-oopherectomy vvas performed. Histopathologic examination of specimen revealed carcinoma infiltration of the right ovary. İn immunohistochemical staining the diffuse and strong positivity vvith cytokeratin (CK) 7 and gross cyctic disease fluid protein (GCDFP-15) vvere detected. The diagnosis of invasive ductal breast carcinoma to the right ovary vvas made by morphological, IHC and clinical findings. She vvas received four cycles chemotherapy, postoperatively. The patient vvas follovved-up vvithout relapse vvithin 21 months under hormonotherapy. İn patients vvith breast cancer, when a mass is detected in ovaries or pelvic region, not only primary ovarian cancer, but metastatic breast carcinoma to ovaries should be kept in mind.

Keywords

Breast cancer, metastatic ovarian cancer, anastrazole.

A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy

Year 2010, Volume: 43 Issue: 1, 42 - 45, 01.04.2010

Ahmet Bilici Mesut Şeker Başak Bala Ustaalioğlu Öven Tarık Salman Taflan Salepçi Dilek Yavuzer Mahmut Gümüş

Abstract

Över metastazı, en sık genital organlardan ardından sırayla gastrointestinal sistem ve meme karsinomundan gerçekleşir. Bu yazıda, meme kanseri nedeniyle adjuvan tedavilerini aldıktan sonra adjuvan anastrazol tedavisi altında takip edilirken, yedi yıl sonra izole över metastazı saptanan nüks meme kanseri olgusu sunuldu. Hasta sağ alt karın ağrısı ile başvurdu. Yapılan radyolojik incelemelerde uterus içerisinde miyoma uteri ile uyumlu kitle saptandı. Hastaya total abdominal histerektomi ve bilateral salpingooferektomi uygulandı. Histopatolojik incelemede sağ överde karsinom infiltrasyonu saptandı. Alınan dokuların immünhistokimyasal (İHK) incelemesinde, tümör hücrelerinde sitokeratin (CK) 7 ile ve gross cyctic disease fluid protein (GCDFP-15) ile yaygın ve kuvvetli pozitiflik saptandı. Morfolojik, İHK ve klinik bulgular eşliğinde hastaya invaziv duktal karsinomun över metastazı tanısı konuldu. Postoperatif dört kür kemoterapi uygulanan hasta 21. ayında halen hormonoterapi altında hastalıksız olarak izlenmektedir. Meme kanserli hastalarda överlerde ya da pelvisde kitle saptandığında, primer över kanseri olabileceği gibi meme kanserine bağlı över metastazı olabileceği de akılda tutulmalıdır.

Keywords

Meme kanseri, metastatik över kanseri, anastrazol.

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Details

Primary Language	Turkish
Journal Section	Articles
Authors	Ahmet Bilici This is me Mesut Şeker This is me Başak Bala Ustaalioğlu Öven This is me Tarık Salman This is me Taflan Salepçi This is me Dilek Yavuzer This is me Mahmut Gümüş This is me
Publication Date	April 1, 2010
Published in Issue	Year 2010 Volume: 43 Issue: 1

Cite

APA	Bilici, A. ., Şeker, M. ., Öven, B. B. U. ., Salman, T. ., et al. (2010). A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy. Acta Oncologica Turcica, 43(1), 42-45.
AMA	Bilici A, Şeker M, Öven BBU, Salman T, Salepçi T, Yavuzer D, Gümüş M. A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy. Acta Oncologica Turcica. April 2010;43(1):42-45.
Chicago	Bilici, Ahmet, Mesut Şeker, Başak Bala Ustaalioğlu Öven, Tarık Salman, Taflan Salepçi, Dilek Yavuzer, and Mahmut Gümüş. “A Case of Recurrent Breast Cancer Diagnosed Vvith Isolated Ovarian Metastasis Under Anastrazole Therapy”. Acta Oncologica Turcica 43, no. 1 (April 2010): 42-45.
EndNote	Bilici A, Şeker M, Öven BBU, Salman T, Salepçi T, Yavuzer D, Gümüş M (April 1, 2010) A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy. Acta Oncologica Turcica 43 1 42–45.
IEEE	A. . Bilici, “A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy”, Acta Oncologica Turcica, vol. 43, no. 1, pp. 42–45, 2010.
ISNAD	Bilici, Ahmet et al. “A Case of Recurrent Breast Cancer Diagnosed Vvith Isolated Ovarian Metastasis Under Anastrazole Therapy”. Acta Oncologica Turcica 43/1 (April 2010), 42-45.
JAMA	Bilici A, Şeker M, Öven BBU, Salman T, Salepçi T, Yavuzer D, Gümüş M. A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy. Acta Oncologica Turcica. 2010;43:42–45.
MLA	Bilici, Ahmet et al. “A Case of Recurrent Breast Cancer Diagnosed Vvith Isolated Ovarian Metastasis Under Anastrazole Therapy”. Acta Oncologica Turcica, vol. 43, no. 1, 2010, pp. 42-45.
Vancouver	Bilici A, Şeker M, Öven BBU, Salman T, Salepçi T, Yavuzer D, Gümüş M. A Case of Recurrent Breast Cancer Diagnosed vvith Isolated Ovarian Metastasis Under Anastrazole Therapy. Acta Oncologica Turcica. 2010;43(1):42-5.