Ekstraskeletal Osteosarkom: Olgu Sunumu

Year 2011, Volume: 44 Issue: 2, 2 - 3, 01.08.2011

Fisun Ardıç Yükrük Fatma Markoç Ayşe Şerife Salan Berkel Elife Aktaş

https://doi.org/10.5505/aot.2011.17363

Abstract

Extraosseöz osteosarkom (ESOS), yumuşak dokunun osteoid, kemik ya da kondroid materyal üreten malign mezenkimal neoplazmı olarak tanımlanan nadir görülen tümörüdür. Tüm yumuşak doku sarkomlarının %1.2'sini (1), tüm osteosarkomların ise %4'inden azını oluşturur (2,13). Tümör temel olarak retroperiton ve ekstremitelerin yumuşak dokusunda görülür ve kemik ya da periosteum ile ilşkisi yoktur. Kemiğin osteosarkomu ilk iki dekatta görülmesine karşın, ESOS 40 yaşın üzerindeki hastalarda görülür. Meme, deri, mesane, akciğer ve mediasten, dil, spermatik kord ve penis, cerebrum, kolon ESOS'un bildirilmiş olağandışı lokalizasyonlarıdır (3-12).Sunulan olguda histopatolojik olarak epiteloid ve iğsi hücrelerin arasında fokal olarak osteoid üretimi nedeniyle ESOS tanısı verilmiştir.

Keywords

osteosarkom, ekstraosseöz

Extraskeletal Osteosarcoma: A Case Report

Abstract

Extraskeletal osteosarcoma is a rare high grade malign mesenchymal tumor with osteoid, bone and chondroid matrix.It accounts for 1.2 % (1)of all soft tissue tumors and less than 4 % of osteosarcomas (2,13).The tumor occurs principally in soft tissue of retroperitoneum and extremities without any attachment to the underlying bone and periosteum.In contrast to the other subtypes of osteosarcoma which is seen in the first two decades, ESOS most commonly occurs in patients over 40 years old. Breast, skin, bladder, lung and mediastinum, tongue, spermatic cord and penis, cerebrum and colon are other extraordinary localisations of ESOS (3-12).Histopathologically the tumor showed proliferation of epithelioid and spindle shaped tumor cells focally forming lace like osteoid material. Therefore, a definite diagnosis of ESOS was made.

Keywords

osteosarcoma, extraskeletal

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