Abstract
The metastasis of glioblastoma multiforme (GBM) to spine via cerebrospinal fluid pathways is not often. We present an intracranial GBM case metastasized to spine after local treatment of cranial lesion with surgery and chemoradiotherapy. One year after the first presentation of cranial GBM, patient presented low back pain and lower limb weakness. Lomber magnetic resonance imaging (MRI) examination demonstrated L1 intradural mass. Excisional biopsy showed GBM.
Keywords
References
- Hübner F, Braun V, Richter HP. Case Report of Symptomatic metastases in four patients with primary intracranial gliomas. Acta Neurochir (Wien) 2001;143:25-9 2. Birbilis TA, Matis GK, Eleftheriadis SG, Theodoropoulou EN, Sivridis E. Spinal metastasis of glioblastoma multiforme: an uncommon suspect? Spine (Phila Pa 1976) 2010;35:264-9
- Karaca M, Andrieu MN, Hicsonmez A, et al. Cases of glioblastoma multiforme metastasing to spinal cord. Neurol India 2006;54:428-30.
- Giese A,Westphal M. Glioma invasion in the central nervous system. Neurosurgery 1996;39:235-52
- Stanley P, Senac MO Jr, Segall HD. Intraspinal seeding from intracranial tumors in children. Am J Roentgenol 1985;144:157-61
- Mihara F, Ikeda M, Rothman MI, Numaguchi Y, Kristt D. Vertebral body metastasis of glioblastoma multiforme with epidural mass formation. Contrast- mediated MRI study. Clin Imaging 1994;18:386-9
- Alatakis S, Malhalm G, Thien C. Spinal leptomeningeal glioblastoma multiforme presenting with radicular pain: Case report and literature review. Surgical Neurology 2001;56:33-7 from cerebral
- Grabb PA, Albright AL, Pang D. Dissemination of supratentorial cerebrospinal fluid in children. Neurosurgery 1992:30:64-71 gliomas via the
- Vertosick FT, Selker RG. Brainstem and spinal metastases multiforme: 1990;27:516-22 glioblastoma Neurosurgery clinical series.
Abstract
Glioblastoma multiformenin (GBM) serebrospinal sıvı yolakları aracılığı ile omurgaya metastazı sık görülen bir durum değildir. Biz burada cerrahi ve kemoradyoterapi ile lokal tedavisinden sonra omurgaya metastaz yapan bir intrakaranial GBM vakasını sunduk. Hasta kranial GBM ile ilk gelişinden bir yıl sonra bel ağrısı ve alt ekstremitelerde güçsüzlükle başvurdu. Lomber magnetik rezonans görüntüleme incelemesinde L1'de intradural kitle izlendi. Yapılan eksizyonel biyopside GBM gösterildi.
Keywords
References
- Hübner F, Braun V, Richter HP. Case Report of Symptomatic metastases in four patients with primary intracranial gliomas. Acta Neurochir (Wien) 2001;143:25-9 2. Birbilis TA, Matis GK, Eleftheriadis SG, Theodoropoulou EN, Sivridis E. Spinal metastasis of glioblastoma multiforme: an uncommon suspect? Spine (Phila Pa 1976) 2010;35:264-9
- Karaca M, Andrieu MN, Hicsonmez A, et al. Cases of glioblastoma multiforme metastasing to spinal cord. Neurol India 2006;54:428-30.
- Giese A,Westphal M. Glioma invasion in the central nervous system. Neurosurgery 1996;39:235-52
- Stanley P, Senac MO Jr, Segall HD. Intraspinal seeding from intracranial tumors in children. Am J Roentgenol 1985;144:157-61
- Mihara F, Ikeda M, Rothman MI, Numaguchi Y, Kristt D. Vertebral body metastasis of glioblastoma multiforme with epidural mass formation. Contrast- mediated MRI study. Clin Imaging 1994;18:386-9
- Alatakis S, Malhalm G, Thien C. Spinal leptomeningeal glioblastoma multiforme presenting with radicular pain: Case report and literature review. Surgical Neurology 2001;56:33-7 from cerebral
- Grabb PA, Albright AL, Pang D. Dissemination of supratentorial cerebrospinal fluid in children. Neurosurgery 1992:30:64-71 gliomas via the
- Vertosick FT, Selker RG. Brainstem and spinal metastases multiforme: 1990;27:516-22 glioblastoma Neurosurgery clinical series.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | August 1, 2011 |
| Published in Issue | Year 2011 Volume: 44 Issue: 2 |