Evaluation of the Toxicity Activity of Bioactive Compounds of Some Geophytes against Brine Shrimp (Artemia salina L.)

Year 2021, Volume: 17 Issue: 2, 195 - 201, 01.06.2021

Murat Turan , Ramazan Mammadov

https://doi.org/10.22392/actaquatr.791297

Cited By: 1

Abstract

Artemia salina L.is an important model organism for the world ecosystem, which is very sensitive, easily available, allows to work in the laboratory environment, is used in toxic effect studies, and gives safe results. This study was designed to evaluate the toxic effect of water extract of fresh and underground parts of some species of five geophyte genera (Arum rupicola var. virescens (Stapf) P.C. Boyce, Cyclamen cilicium Boiss. & Heldr, Gagea bohemica (Zauschn.) Schult. & Schult. f., Narcissus tazetta subsp. tazetta L., Paeonia kesrouanensis J. Thiébaut) against A. salina. All taxa were found to be more toxic in the fresh part than in the underground part. The fresh part of P. kesrouanensis was shown the highest toxic effect with 44.44 ± 2.78% (1.56 ± 0.13 mg/mL, LC50) and the underground part of N. tazetta subsp. tazetta was shown the lowest toxic effect with 8.33 ± 0.00% (294.68 ± 1.54 mg/mL, LC50). The underground part of N. tazetta subsp. tazetta and Gagea bohemica were not found toxic with > 1000 mg/ml, LC90. Based on the studies showing that A. salina toxic effect studies are related to insecticide and anticancer studies, it is seen that especially the fresh part of P. kesrouanensis has potential insecticide and anticancer properties, but more studies are needed.

Keywords

Artemia salina (L.), Toxicity effect, Narcissus tazetta subsp. tazetta, Paeonia kesrouanensis

Supporting Institution

Scientific Research Projects (BAP) of Pamukkale University, Denizli, Turkey

Project Number

Project No: 2019FEBE001

Bazı Geofit Türlerin Biyoaktif Bileşiklerinin Tuzlu Su Karidesi (Artemia salina)'ne Karşı Toksisite Aktivitesinin Değerlendirilmesi

Abstract

Artemia salina L. çok hassas, kolay ulaşılabilir, laboratuvar ortamında in vivo çalışmaya olanak sağlayan, toksik etki çalışmalarında kullanılıp güvenli sonuçlar veren, dünya ekosistemi için önemli bir model organizmadır. Bu çalışma, geofit olan beş cinse ait bazı türlerin (Arum rupicola var. virescens (Stapf) P.C. Boyce, Cyclamen cilicium Boiss. & Heldr, Gagea bohemica (Zauschn.) Schult. & Schult. f., Narcissus tazetta subsp. tazetta L., Paeonia kesrouanensis J. Thiébaut) toprak üstü ve toprak altı kısımlarının su ekstraktının A. salina’ya karşı toksik etkisini değerlendirmek için tasarlanmıştır. Bütün taksonlarda toprak üstü kısım, toprak altı kısıma göre daha toksik olduğu bulunmuştur. P. kesrouanensis’in toprak üstü kısmı 44.44 ± 2.78% (1.56 ± 0.13 mg/mL, LC50) değeri ile en yüksek toksik etkiyi gösterirken N. tazetta subsp. tazetta’nın toprak altı kısmı 8.33 ± 0.00% (294.68 ± 1.54 mg/mL, LC50) değeri ile en düşük toksik etkiyi göstermiştir. N. tazetta subsp. tazetta ve G. bohemica’nın toprak altı kısmı > 1000 mg/ml, LC90 ile toksik bulunmamıştır. A. salina toksik etki çalışmalarının insektisit ve antikanser çalışmaları ile ilgili olduğunu gösteren çalışmalara dayanarak, özellikle P. kesrouanensis'in yer üstü kısmının potansiyel insektisit ve antikanser özelliklere sahip olduğu ancak daha fazla çalışmaya ihtiyaç duyulduğu görülmüştür.

Keywords

Artemia salina (L.), Toksik etki, Narcissus tazetta subsp. tazetta, Paeonia kesrouanensis

Project Number

Project No: 2019FEBE001

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