COMMON CYSTIC LESIONS ON THE JAWS IN CHILDHOOD

Abstract

Although cystic lesions are frequently observed in the jaws, their distribution differs between children and adults. During childhood, the three-dimensional growth of the maxillofacial skeleton and the developmental process including the odontogenesis of the teeth affect the distribution of cysts. Knowing the clinical and radiographic findings of cystic lesions, which can be observed frequently in the jaws in this period, is important in terms of making their differential diagnosis and applying the appropriate treatment method. Thus, it is thought that the negative effects of cystic lesions on maxillofacial development can be prevented. In this review, the clinical, radiological, histological features, diagnosis, and treatment methods of cystic lesions, which are common in the jaws in childhood, will be examined.

Keywords

• childhood
• cystic lesion
• mandible
• maxilla

ÇOCUKLUK DÖNEMİNDE ÇENELERDE SIK GÖRÜLEN KİSTİK LEZYONLAR

Abstract

Kistik lezyonlar çenelerde sıklıkla gözlenmekle birlikte dağılımı çocuklar ve yetişkinler arasında farklılık göstermektedir. Çocukluk döneminde maksillofasiyal iskeletin üç boyutlu büyümesi ve dişlerin odontogenezisini içeren gelişim süreci kistlerin dağılımını etkilemektedir. Bu dönemde çenelerde sıklıkla gözlenebilecek kistik lezyonların klinik ve radyografik bulgularının iyi bilinmesi, ayrıcı tanılarının yapılabilmesi ve uygun tedavi yönteminin gerçekleştirilebilmesi açısından önemlidir. Böylece kistik lezyonların maksillofasiyal gelişim üzerindeki olumsuz etkilerinin önlenebileceği düşünülmektedir. Bu derlemede çocukluk döneminde çenelerde sık görülen kistik lezyonların klinik, radyolojik, histolojik özellikleri, tanı ve tedavi yöntemleri incelenecektir.

Keywords

• Çocukluk Dönemi
• Maksilla
• Mandibula
• Kistik Lezyon

References

1. Referans1. Manor E, Kachko L, Puterman MB, Szabo G, Bodner L. Cystic lesions of the jaws - a clinicopathological study of 322 cases and review of the literature. Int J Med Sci. 2012;9(1):20-6.
2. Referans2. Tkaczuk AT, Bhatti M, Caccamese JF, Ord RA, Pereira KD. Cystic lesions of the jaw in children: A 15-Year Experience. JAMA Otolaryngol Head Neck Surg. 2015;141(9):834-9.
3. Referans3. Iatrou I, Theologie-Lygidakis N, Leventis M. Intraosseous cystic lesions of the jaws in children: a retrospective analysis of 47 consecutive cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(4):485-92.
4. Referans4. Bodner L. Cystic lesions of the jaws in children. Int J Pediatr Otorhinolaryngol. 2002;62(1):25-9.
5. Referans5. Wang YL, Chang HH, Chang J, Huang GF, Guo MK. Retrospective Survey of Biopsied Oral Lesions in Pediatric Patients. J Formos Med Assoc. 2009;108(11):862-71.
6. Referans6. Parkar MI, Belgaumi U, Suresh KV, Landge JS, Bhalinge PM, Dawoodbhoy RI. Bilaterally symmetrical infected radicular cysts: Case report and review of literature. J Oral Maxillofac Surg Med Pathol. 2017;29(5):458-62.
7. Referans7. Tekkesin MS, Olgac V, Aksakalli N, Alatli C. Odontogenic and nonodontogenic cysts in Istanbul: analysis of 5088 cases. Head Neck. 2012;34(6):852-5.
8. Referans8. Jones AV, Franklin CD. An analysis of oral and maxillofacial pathology found in children over a 30-year period. Int J Paediatr Dent. 2006;16(1):19-30.

9. Referans9. Rajendra Santosh AB. Odontogenic Cysts. Dent Clin North Am. 2020;64(1):105-19.
10. Referans10. Ramachandran Nair PN, Pajarola G, Schroeder HE. Types and incidence of human periapical lesions obtained with extracted teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;81(1):93-102.
11. Referans11. Nair PN, Pajarola G, Luder HU. Ciliated epithelium-lined radicular cysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94(4):485-93.
12. Referans12. Tournas A, Tewfik M, Chauvin P, Manoukian J. Multiple unilateral maxillary dentigerous cysts in a non-syndromic patient: A case report and review of the literature. Int J Pediatr Otorhinolaryngol Extra. 2006;1(2):100-6.
13. Referans13. Murakami A, Kawabata K, Suzuki A, Murakami S, Ooshima T. Eruption of an impacted second premolar after marsupialization of a large dentigerous cyst: case report. Pediatr Dent. 1995;17(5):372-4.
14. Referans14. Delbem AC, Cunha RF, Afonso RL, Bianco KG, Idem AP. Dentigerous cysts in primary dentition: report of 2 cases. Pediatr Dent. 2006;28(3):269-72.
15. Referans15. Milani C, Thomé C, Pompermayer A, Sarot J, Vinagre R, Machado M. Marsupialization of Dentigerous Cyst: Report of a Case. J Maxillofac Oral Surg. 2015;14(1):4-6.
16. Referans16. Tamgadge A, Tamgadge S, Bhatt D, Bhalerao S, Pereira T, Padhye M. Bilateral dentigerous cyst in a non-syndromic patient: Report of an unusual case with review of the literature. J Oral Maxillofac Pathol. 2011;15(1):91-5.
17. Referans17. Ko KS, Dover DG, Jordan RC. Bilateral dentigerous cysts--report of an unusual case and review of the literature. J Can Dent Assoc. 1999;65(1):49-51.
18. Referans18. Koca H, Esin A, Aycan K. Outcome of dentigerous cysts treated with marsupialization. J Clin Pediatr Dent. 2009;34(2):165-8.
19. Referans19. Wright JM, Vered M. Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors. Head Neck Pathol. 2017;11(1):68-77.
20. Referans20. Myoung H, Hong S-P, Hong S-D, Lee J-I, Lim C-Y, Choung P-H, et al. Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;91(3):328-33.
21. Referans21. Borghesi A, Nardi C, Giannitto C, Tironi A, Maroldi R, Di Bartolomeo F. Odontogenic keratocyst: imaging features of a benign lesion with an aggressive behaviour. Insights into imaging. 2018;9(5):883-97.
22. Referans22. Smith AJ, Browne RM. Analysis of odontogenic keratocyst fluids for preoperative diagnosis. J Clin Pathol. 1987;40(3):354-5.
23. Referans23. Mendes RA, Carvalho JF, van der Waal I. Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol. 2010;46(4):219-25.
24. Referans24. Tarakji B, Baroudi K, Hanouneh S, Azzeghaiby SN, Nassani MZ. Possible recurrence of keratocyst in nevoid basal cell carcinoma syndrome: A review of literature. Eur J Dent. 2013;7:126-34.
25. Referans25. Patidar M, Shetty P, Patidar N, Mittal S, Singh H, Chethna. Biochemical and cytological comparison of keratocystic odontogenic tumours to nonkeratinising odontogenic cysts fluid. J Clin Diagn Res. 2015;9(7):ZC34-ZC8.
26. Referans26. Barnes L, Eveson JW, Reichart P, Sidransky D.(Eds.) World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours. IARC Press, Lyon, France, 2005:326-7
27. Referans27. Kaugars GE, Cale AE. Traumatic bone cyst. Oral Surg Oral Med Oral Pathol. 1987;63(3):318-24.
28. Referans28. Matsumura S, Murakami S, Kakimoto N, Furukawa S, Kishino M, Ishida T, et al. Histopathologic and radiographic findings of the simple bone cyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85(5):619-25.
29. Referans29. Wakasa T, Kawai N, Aiga H, Kishi K. Management of florid cemento-osseous dysplasia of the mandible producing solitary bone cyst: report of a case. J Oral Maxillofac Surg. 2002;60(7):832-5.
30. Referans30. An SY, Lee JS, Benavides E, Aminlari A, McDonald NJ, Edwards PC, et al. Multiple simple bone cysts of the jaws: review of the literature and report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117(6):458-69.
31. Referans31. Bodner L, Goldstein J, Sarnat H. Eruption cysts: a clinical report of 24 new cases. J Clin Pediatr Dent. 2004;28(2):183-6.
32. Referans32. Figueiredo N, Meena M, Ajit D D, Khorate M, Satoskar S. Eruption Cyst: A Case Report. Ann Essence Dent. 2013;5:9-11.
33. Referans33. De Oliveira AJ, Silveira ML, Duarte DA, Diniz MB. Eruption cyst in the neonate. Int J Clin Pediatr Dent. 2018;11(1):58-60.
34. Referans34. Dhawan P, Kochhar GK, Chachra S, Advani S. Eruption cysts: A series of two cases. Dent Res J (Isfahan). 2012;9(5):647-50.
35. Referans35. Regezi JA, Sciubba J, Jordan RC. Oral pathology: clinical pathologic correlations: Elsevier Health Sciences; 2016.
36. Referans36. Resende RG, Brito JA, Souza LN, Gomez RS, Mesquita RA. Peripheral calcifying odontogenic cyst: a case report and review of the literature. Head Neck Pathol. 2011;5(1):76-80.
37. Referans37. Uzun T, Çinpolat E. Calcifying odontogenic cyst associated with the impacted third molar: a case report. The Pan Afr Med J. 2019;33:1-5.
38. Referans38. White SC, Pharoah MJ. Oral radiology-E-Book: Principles and interpretation: Elsevier Health Sciences; 2014.
39. Referans39. Moleri AB, Moreira LC, Carvalho JJ. Comparative morphology of 7 new cases of calcifying odontogenic cysts. J Oral Maxillofac Surg. 2002;60(6):689-96.
40. Referans40. Nagao T, Nakajima T, Fukushima M, Ishiki T. Calcifying odontogenic cyst with complex odontoma. J Oral Maxillofac Surg. 1982;40(12):810-3.
41. Referans41. Arruda J-A, Silva L-V, Silva L, Monteiro J-L, Álvares P, Silveira M, et al. Calcifying odontogenic cyst: A 26-year retrospective clinicopathological analysis and immunohistochemical study. J Clin Exp Dent. 2018;10(6):542-7.
42. Referans42. Buchner A, Merrell PW, Carpenter WM, Leider AS. Central (intraosseous) calcifying odontogenic cyst. Int J Oral Maxillofac Surg. 1990;19(5):260-2.
43. Referans43. Cottalorda J, Bourelle S. Modern concepts of primary aneurysmal bone cyst. Arch Orthop Trauma Surg. 2007;127(2):105-14.
44. Referans44.Lau AW, Pringle LM, Quick L, Riquelme DN, Ye Y, Oliveira AM. TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation. J Biol Chem. 2010;285(47):37111-20.
45. Referans45. Motamedi MH. Destructive aneurysmal bone cyst of the mandibular condyle: report of a case and review of the literature. J Oral Maxillofac Surg. 2002;60(11):1357-61.
46. Referans46. Park HY, Yang SK, Sheppard WL, Hegde V, Zoller SD, Nelson SD. Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016;9(4):435-44.
47. Referans47. Sun ZJ, Sun HL, Yang RL, Zwahlen RA, Zhao YF. Aneurysmal bone cysts of the jaws. Int J Surg Pathol. 2009;17(4):311-22.
48. Referans48. Bharadwaj G, Singh N, Gupta A, Sajjan AK. Giant aneurysmal bone cyst of the mandible: A case report and review of literature. Natl J Maxillofac Surrg. 2013;4(1):107-10.