Uyku ve Bruksizm: Kompleks ve İlginç Bir İlişki

Abstract

Bruksizm, uyku veya uyanıklık sırasında diş gıcırdatma veya sıkma ile karakterize parafonksiyonel bir alışkanlıktır. Uyku, bruksizm patogenezinde çok önemli bir faktördür ve çeşitli çalışmalar bruksizm ile obstrüktif uyku apnesi ve uykusuzluk gibi uyku bozuklukları arasında bir ilişki olduğunu bildirmektedir. Ek olarak bruksizm, horlama, uyku bölünmesi ve gündüz uyku hali gibi çeşitli uyku ile ilgili semptomların ortaya çıkmasıyla ilişkilendirilmiştir. Ayrıca uyku kalitesi ve miktarı da bruksizm ataklarının sıklığını ve şiddetini etkileyebilir. Araştırmalar, düşük uyku kalitesi ve yetersiz uyku süresi olan bireylerin bruksizm davranışları sergileme olasılığının daha yüksek olduğunu göstermiştir. Uyku ve bruksizm arasındaki ilişki biyolojik, psikolojik ve çevresel faktörleri içeren karmaşık ve çok faktörlüdür. Uyku ve bruksizmi birbirine bağlayan altta yatan mekanizmaların belirlenmesi, bruksizm için etkili tanısal ve terapötik yaklaşımların geliştirilmesine yardımcı olabilir. Bu gözden geçirme, klinik ve deneysel çalışmalardan elde edilen önemli bulguları vurgulayarak, uyku ve bruksizm arasındaki ilişki hakkındaki mevcut bilgilere kapsamlı bir genel bakış sunmayı amaçlamaktadır. Bu makale aynı zamanda bruksizmin gelişimi, ilerlemesi ve yönetiminde uyku ile ilgili faktörlerin potansiyel etkilerini tartışmaktadır. Genel olarak, kanıtlar bruksizmin uyku bozuklukları ile güçlü bir şekilde ilişkili olduğunu ve klinisyenlerin bruksizmli bireylerde altta yatan uyku bozuklukları olasılığını göz önünde bulundurması gerektiğini göstermektedir.

Keywords

• bruksizm
• uyku
• temporomandibular eklem hastalıkları

Sleep and Bruxism: A Complex and Compelling Relationship

Abstract

Bruxism is a parafunctional habit characterized by grinding or clenching of teeth during sleep or wakefulness. Sleep is a crucial factor in the pathogenesis of bruxism, with several studies reporting an association between bruxism and sleep disorders such as obstructive sleep apnea and insomnia. In addition, bruxism has been linked to the occurrence of various sleep-related symptoms, such as snoring, sleep fragmentation, and daytime sleepiness. Furthermore, sleep quality and quantity may also affect the frequency and severity of bruxism episodes. Studies have shown that individuals who experience poor sleep quality and insufficient sleep duration are more likely to exhibit bruxism behaviors. The relationship between sleep and bruxism is complex and multifactorial, involving biological, psychological, and environmental factors. Identifying the underlying mechanisms linking sleep and bruxism may aid in the development of effective diagnostic and therapeutic approaches for bruxism. This review aims to provide a comprehensive overview of the current knowledge on the relationship between sleep and bruxism, highlighting the key findings from clinical and experimental studies. The paper also discusses the potential implications of sleep-related factors in the development, progression, and management of bruxism. Overall, the evidence suggests that bruxism is strongly associated with sleep disturbances, and that clinicians should consider the possibility of underlying sleep disorders in individuals with bruxism.

Keywords

• bruxism
• sleep
• temporomandibular joint disorders

References

1. American Academy of Sleep Medicine. 2014. International Classification of Sleep Disorders, 3rd ed. Darien, IL: American Academy of Sleep Medicine.
2. Lobbezoo F, Ahlberg J, Glaros AG, Kato T, Koyano K, Lavigne GJ, de Leeuw R, Manfredini D, Svensson P, Winocur E. Bruxism defined and graded: an international consensus. J Oral Rehabil. 2013 Jan;40(1):2-4. doi: 10.1111/joor.12011.
3. Manfredini D, Lobbezoo F. Role of psychosocial factors in the etiology of bruxism. J Orofac Pain. 2009 Spring;23(2):153-66.
4. Hirshkowitz M, Whiton K, Albert SM, Alessi C, Bruni O, DonCarlos L, Hazen N, Herman J, Adams Hillard PJ, Katz ES, Kheirandish-Gozal L, Neubauer DN, O’Donnell AE, Ohayon M, Peever J, Rawding R, Sachdeva RC, Setters B, Vitiello MV, Ware JC. National Sleep Foundation’s updated sleep duration recommendations: final report. Sleep Health. 2015 Dec;1(4):233-243. doi: 10.1016/j.sleh.2015.10.004.
5. Lim J, Dinges DF. Sleep deprivation and vigilant attention. Ann N Y Acad Sci. 2008;1129:305-22. doi: 10.1196/annals.1417.002.
6. Philip P, Sagaspe P, Taillard J, Valtat C, Moore N, Akerstedt T, Charles A, Bioulac B. Fatigue, sleepiness, and performance in simulated versus real driving conditions. Sleep. 2005 Dec;28(12):1511-6. doi: 10.1093/ sleep/28.12.1511.
7. Cappuccio FP, Cooper D, D’Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J. 2011 Jun;32(12):1484-92. doi: 10.1093/eurheartj/ehr007.
8. Irwin MR. Why sleep is important for health: a psychoneuroimmunology perspective. Annu Rev Psychol. 2015 Jan 3;66:143-72. doi: 10.1146/annurevpsych- 010213-115205.

9. Leproult R, Van Cauter E. Role of sleep and sleep loss in hormonal release and metabolism. Endocr Dev. 2010;17:11-21. doi: 10.1159/000262524.
10. Owens JA, Mindell JA. Pediatric insomnia. Pediatr Clin North Am. 2011 Jun;58(3):555-69. doi: 10.1016/j. pcl.2011.03.011.
11. Lavigne GJ, Khoury S, Abe S, Yamaguchi T, Raphael K. Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil. 2008 Jul;35(7):476-94. doi: 10.1111/j.1365-2842.2008.01881.x.
12. Irwin MR. Sleep and inflammation: partners in sickness and in health. Nat Rev Immunol. 2019 Nov;19(11):702- 715. doi: 10.1038/s41577-019-0190-z.
13. Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch. 2012 Jan;463(1):121-37. doi: 10.1007/s00424-011-1044-0.
14. Manfredini D, Winocur E, Guarda-Nardini L, Paesani D, Lobbezoo F. Epidemiology of bruxism in adults: a systematic review of the literature. J Orofac Pain. 2013 Spring;27(2):99-110. doi: 10.11607/jop.921.
15. Carra MC, Huynh N, Lavigne G. Nocturnal bruxism: a comprehensive overview for the dental clinician interested in sleep medicine. Dent Clin North Am. 2012 Apr;56(2):387-413. doi: 10.1016/j.cden.2012.01.003.
16. Garrett AR, Hawley JS. SSRI-associated bruxism: A systematic review of published case reports. Neurol Clin Pract. 2018 Apr;8(2):135-141. doi: 10.1212/ CPJ.0000000000000433.
17. Murali RV, Rangarajan P, Mounissamy A. Bruxism: Conceptual discussion and review. J Pharm Bioallied Sci. 2015 Apr;7(Suppl 1):S265-70. doi: 10.4103/0975- 7406.155948.
18. Klasser GD, Greene CS. Role of oral appliances in the management of nocturnal bruxism and temporomandibular disorders. Alpha Omegan. 2007;100(3):111-9. doi: 10.1016/j.aodf.2007.07.008. Erratum in: Alpha Omegan. 2007;100(4):219.
19. Lobbezoo F, Ahlberg J, Raphael KG, Wetselaar P, Glaros AG, Kato T, Santiago V, Winocur E, De Laat A, De Leeuw R, Koyano K, Lavigne GJ, Svensson P, Manfredini D. International consensus on the assessment of bruxism: Report of a work in progress. J Oral Rehabil. 2018 Nov;45(11):837-844. doi: 10.1111/joor.12663
20. Martynowicz H, Gac P, Brzecka A, Poreba R, Wojakowska A, Mazur G, Smardz J, Wieckiewicz M. The Relationship between Nocturnal bruxism and Obstructive Sleep Apnea Based on Polysomnographic Findings. J Clin Med. 2019 Oct 11;8(10):1653. doi: 10.3390/jcm8101653.
21. Gauer RL, Semidey MJ. Diagnosis and treatment of temporomandibular disorders. Am Fam Physician. 2015 Mar 15;91(6):378-86.
22. Cappuccio FP, Cooper D, D’Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: A systematic review and meta-analysis of prospective studies. Eur Heart J. 2011;32(12):1484-1492. doi: 10.1093/eurheartj/ehr007
23. Grandner MA, Jackson N, Gerstner JR, Knutson KL. Sleep symptoms associated with intake of specific dietary nutrients. J Sleep Res. 2014 Feb;23(1):22-34. doi: 10.1111/jsr.12084.
24. Hirshkowitz M, Whiton K, Albert SM, Alessi C, Bruni O, DonCarlos L, Hazen N, Herman J, Katz ES, Kheirandish-Gozal L, Neubauer DN, O’Donnell AE, Ohayon M, Peever J, Rawding R, Sachdeva RC, Setters B, Vitiello MV, Ware JC, Adams Hillard PJ. National Sleep Foundation’s sleep time duration recommendations: methodology and results summary. Sleep Health. 2015 Mar;1(1):40-43. doi: 10.1016/j.sleh.2014.12.010.
25. Dijk DJ, Duffy JF. Circadian regulation of human sleep and age-related changes in its timing, consolidation and EEG characteristics. Ann Med. 1999 Apr;31(2):130- 40. doi: 10.3109/07853899908998789.
26. Peever J, Fuller PM. The Biology of REM Sleep. Curr Biol. 2017 Nov 20;27(22):R1237-R1248. doi: 10.1016/j. cub.2017.10.026. PMID: 29161567.
27. Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004 Dec;1(3):e62. doi: 10.1371/journal.pmed.0010062.
28. Morin CM, Drake CL, Harvey AG, Krystal AD, Manber R, Riemann D, Spiegelhalder K. Insomnia disorder. Nat Rev Dis Primers. 2015 Sep 3;1:15026. doi: 10.1038/nrdp.2015.26.
29. Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013 May 1;177(9):1006-14. doi: 10.1093/aje/kws342.
30. Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW, Zucconi M, Ferri R, Trenkwalder C, Lee HB; International Restless Legs Syndrome Study Group. Restless legs syndrome/Willis- Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. Sleep Med. 2014 Aug;15(8):860-73. doi: 10.1016/j.sleep.2014.03.025.
31. Dauvilliers Y, Barateau L. Narcolepsy and Other Central Hypersomnias. Continuum (Minneap Minn). 2017 Aug;23(4, Sleep Neurology):989-1004. doi: 10.1212/ CON.0000000000000492.
32. Kato T, Thie NM, Huynh N, Miyawaki S, Lavigne GJ. Topical review: nocturnal bruxism and the role of peripheral sensory influences. J Orofac Pain. 2003 Summer;17(3):191-213.
33. Ohayon MM, Li KK, Guilleminault C. Risk factors for nocturnal bruxism in the general population. Chest. 2001 Jan;119(1):53-61. doi: 10.1378/chest.119.1.53.
34. Bader G, Lavigne G. Nocturnal bruxism; an overview of an oromandibular sleep movement disorder. REVIEW ARTICLE. Sleep Med Rev. 2000 Feb;4(1):27-43. doi: 10.1053/smrv.1999.0070.
35. Ciancaglini R, Gherlone EF, Radaelli G. The relationship of bruxism with craniofacial pain and symptoms from the masticatory system in the adult population. J Oral Rehabil. 2001 Sep;28(9):842-8. doi: 10.1046/j.1365-2842.2001.00753.x.
36. Jokubauskas L, Baltrušaitytė A. Relationship between obstructive sleep apnoea syndrome and nocturnal bruxism: a systematic review. J Oral Rehabil. 2017 Feb;44(2):144- 153. doi: 10.1111/joor.12468.
37. Lavigne GJ, Kato T, Kolta A, Sessle BJ. Neurobiological mechanisms involved in nocturnal bruxism. Crit Rev Oral Biol Med. 2003;14(1):30-46. doi: 10.1177/154411130301400104.
38. Kuang B, Li D, Lobbezoo F, de Vries R, Hilgevoord A, de Vries N, Huynh N, Lavigne G, Aarab G. Associations between nocturnal bruxism and other sleep-related disorders in adults: a systematic review. Sleep Med. 2022 Jan;89:31-47. doi: 10.1016/j.sleep.2021.11.008.
39. Kato T, Thie NM, Montplaisir JY, Lavigne GJ. Bruxism and orofacial movements during sleep. Dent Clin North Am. 2001 Oct;45(4):657-84.
40. Gagnon Y, Mayer P, Morisson F, Rompré PH, Lavigne GJ. Aggravation of respiratory disturbances by the use of an occlusal splint in apneic patients: a pilot study. Int J Prosthodont. 2004 Jul-Aug;17(4):447-53.
41. Kato T, Lavigne GJ. Nocturnal bruxism: a sleeprelated movement disorder. Sleep Medicine Clinics, 2010, 5.1: 9-35. doi: 10.1016/j.jsmc.2009.09.003.
42. Hosoya H, Kitaura H, Hashimoto T, Ito M, Kinbara M, Deguchi T, Irokawa T, Ohisa N, Ogawa H, Takano-Yamamoto T. Relationship between nocturnal bruxism and sleep respiratory events in patients with obstructive sleep apnea syndrome. Sleep Breath. 2014 Dec;18(4):837-44. doi: 10.1007/s11325-014-0953-5.
43. Carra MC, Huynh N, Morton P, Rompré PH, Papadakis A, Remise C, Lavigne GJ. Prevalence and risk factors of nocturnal bruxism and wake-time tooth clenching in a 7- to 17-yr-old population. Eur J Oral Sci. 2011 Oct;119(5):386-94. doi: 10.1111/j.1600- 0722.2011.00846.x.
44. Tachibana N, Yamanaka K, Kaji R, Nagamine T, Watatani K, Kimura J, Shibasaki H. Nocturnal bruxism as a manifestation of subclinical rapid eye movement sleep behavior disorder. Sleep. 1994 Sep;17(6):555-8.
45. Lavigne GJ, Rompre PH, Montplaisir JY. Nocturnal bruxism: Validity of Clinical Research Diagnostic Criteria in a Controlled Polysomnographic Study. Journal of Dental Research. 1996;75(1):546-552. doi:10.1177/00220345960750010601