MUTAGENIC POTENTIAL OF A SELF-ADHESIVE FLOWABLE COMPOSITE

Year 2016, Volume: 2 Issue: 3, 9 - 15, 01.10.2016

Tuğba Toz Zeliha Aydoğan Duygu Tuncer Emel Karaman

Abstract

Objective: The aim of this study was to assess the
potential mutagenic effects associated to extracts from
current self-adhesive flowable resin composite (Vertise
Flow,Kerr Corp, Orange, CA, USA) that allows
skipping the time-consuming adhesive processes.
Study design: The materials were eluted in dimethyl
sulphoxide and the extracts were tested either after 1
day or 7 day incubation period at 370C. Mutagenic
effects of the materials were tested on Salmonella
typhipmurium strain TA 100 using the standard plate
incorporation assay in the absence of S9 fraction from
rat liver. The data were statistically analyzed using twoway
variance analysis (p<0.05).
Results: The dose of the material and incubation as
well as the interactions between these factors exhibited
varying degrees of influences on the Salmonella
typhipmurium colony number. However no mutagenic
effect was detected for the self-adhesive restorative
material.
Conclusion: It can be concluded that the adhesive
restorative material tested in this study has no mutagenic
potential.

Keywords

mutagenicity, AMES test, Salmonella tphymiruim, self-adhesive composite, bulk fill flowables, adhesive resin

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