Abstract
Objective: The aim of this study was to assess the
potential mutagenic effects associated to extracts from
current self-adhesive flowable resin composite (Vertise
Flow,Kerr Corp, Orange, CA, USA) that allows
skipping the time-consuming adhesive processes.
Study design: The materials were eluted in dimethyl
sulphoxide and the extracts were tested either after 1
day or 7 day incubation period at 370C. Mutagenic
effects of the materials were tested on Salmonella
typhipmurium strain TA 100 using the standard plate
incorporation assay in the absence of S9 fraction from
rat liver. The data were statistically analyzed using twoway
variance analysis (p<0.05).
Results: The dose of the material and incubation as
well as the interactions between these factors exhibited
varying degrees of influences on the Salmonella
typhipmurium colony number. However no mutagenic
effect was detected for the self-adhesive restorative
material.
Conclusion: It can be concluded that the adhesive
restorative material tested in this study has no mutagenic
potential.
References
- Cohen AS, Brown DC. Pathways of the Pulp. In: Cohen S, Burns RC. Orofacial dental pain emergencies: endodontic diagnoses and management. 8th ed. Boston: Mosby, 2002: 31- 75.
- Zillich R, Dowson J. Root canal morphology of mandibular first and second premolars. Oral Surg 1973;36:738-44.
- Prakash R, Nandini S, Ballal, S, Kumar SN, Kandaswamy D. Two-rooted mandibular second premolars: Case report and survey. Indian J Dent Res 2008;19:70-3.
- Slowey RR. Root canal anatomy- Road map to successful endodontics. Dent Clin North Am 1979;23:555-73.
- Patel S, Dawood A, Ford TP, Whaites E. The potential applications of cone beam computed tomography in the management of endodontic problems. Int Endod J 2007; 10:818-30.
- Poorni S, Karumaran C, Indira R. Mandibular first premolar with two roots and three canals. Aust Endod J 2010;36:32–4.
- Fischer GM, Evans CE. A three-rooted mandibular second premolar. Gen Dent 1992; 40:139-40.
- Alberquerque D, Kottoor J, Hammo M. Endodontic and clinical considerations in the management of variable anatomy in mandibular premolars: a literature review. BioMed Res Int 2014; 512574.
- Kim E, Marmo M, Lee CY, Oh NS, Kim IK. An in vivo comparison of working length determination by only Root-ZX apex locator versus combining Root-ZX apex locator with radiographs using a new impression technique. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:79-83.
- VenskutonisT, Plotino G, Juodzbalys G, Mickevičienė L. The importance of cone-beam computed tomography in the management of endodontic problems: a review of the literature. J Endod 2014; 40:1895-901.
Abstract
Objective: The aim of this study was to assess the
potential mutagenic effects associated to extracts from
current self-adhesive flowable resin composite (Vertise
Flow,Kerr Corp, Orange, CA, USA) that allows
skipping the time-consuming adhesive processes.
Study design: The materials were eluted in dimethyl
sulphoxide and the extracts were tested either after 1
day or 7 day incubation period at 370C. Mutagenic
effects of the materials were tested on Salmonella
typhipmurium strain TA 100 using the standard plate
incorporation assay in the absence of S9 fraction from
rat liver. The data were statistically analyzed using twoway
variance analysis (p<0.05).
Results: The dose of the material and incubation as
well as the interactions between these factors exhibited
varying degrees of influences on the Salmonella
typhipmurium colony number. However no mutagenic
effect was detected for the self-adhesive restorative
material.
Conclusion: It can be concluded that the adhesive
restorative material tested in this study has no mutagenic
potential.
References
- Cohen AS, Brown DC. Pathways of the Pulp. In: Cohen S, Burns RC. Orofacial dental pain emergencies: endodontic diagnoses and management. 8th ed. Boston: Mosby, 2002: 31- 75.
- Zillich R, Dowson J. Root canal morphology of mandibular first and second premolars. Oral Surg 1973;36:738-44.
- Prakash R, Nandini S, Ballal, S, Kumar SN, Kandaswamy D. Two-rooted mandibular second premolars: Case report and survey. Indian J Dent Res 2008;19:70-3.
- Slowey RR. Root canal anatomy- Road map to successful endodontics. Dent Clin North Am 1979;23:555-73.
- Patel S, Dawood A, Ford TP, Whaites E. The potential applications of cone beam computed tomography in the management of endodontic problems. Int Endod J 2007; 10:818-30.
- Poorni S, Karumaran C, Indira R. Mandibular first premolar with two roots and three canals. Aust Endod J 2010;36:32–4.
- Fischer GM, Evans CE. A three-rooted mandibular second premolar. Gen Dent 1992; 40:139-40.
- Alberquerque D, Kottoor J, Hammo M. Endodontic and clinical considerations in the management of variable anatomy in mandibular premolars: a literature review. BioMed Res Int 2014; 512574.
- Kim E, Marmo M, Lee CY, Oh NS, Kim IK. An in vivo comparison of working length determination by only Root-ZX apex locator versus combining Root-ZX apex locator with radiographs using a new impression technique. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:79-83.
- VenskutonisT, Plotino G, Juodzbalys G, Mickevičienė L. The importance of cone-beam computed tomography in the management of endodontic problems: a review of the literature. J Endod 2014; 40:1895-901.
Details
| Other ID | JA56RY85NA |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | October 1, 2016 |
| Submission Date | October 1, 2016 |
| Published in Issue | Year 2016 Volume: 2 Issue: 3 |
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