Use of Peracetic Acid As Irrigation Solution in Endodontics: Overview

Year 2025, Volume: 11 Issue: 2, 205 - 214, 31.08.2025

Özge Bekar

Abstract

Success in endodontic treatment is associated with removing microorganisms from the root canal system and preventing reoccurrence of infection. Irrigation of root canals is very effective in the success of endodontic treatment. Sodium hypochlorite (NaOCl) is the most commonly used irrigant during endodontic treatment due to its antimicrobial properties and organic tissue dissolving capacity. However, when used alone, it is not sufficient to remove the inorganic tissue formed. It is recommended to use NaOCl together with chelating agents as an ideal irrigation protocol to enhance antisepsis and avoid the limitations of commonly used solutions. However, this protocol requires a long clinical time. Moreover, it is known that the combined use of NaOCI and some chelation agents can cause changes in the mineral and organic content of dentin, erosion and a decrease in the microhardness of dentin. Using an irrigation agent that acts as both a chelating and antimicrobial actions can be a good alternative and save time during treatment. Peracetic acid (PAA) is a candidate to be an alternative irrigation solution thanks to its antimicrobial activity and ability to remove the smear layer. This review aims to present the properties of this irrigation solution by examining the studies investigating the effectiveness and applicability of PAA in endodontic practice.

Keywords

Chelating agents , Peracetic acid , Root canal therapy

Perasetik Asitin Endodontide İrrigasyon Solüsyonu Olarak Kullanımı: Genel Bakış

Abstract

Endodontik tedavide başarı, kök kanal sisteminden mikroorganizmaların uzaklaştırılması ve enfeksiyonun tekrar oluşmasının önlenmesi ile ilişkilidir. Kök kanallarının irrigasyonu, endodontik tedavinin başarısında oldukça etkilidir. Sodyum hipoklorit (NaOCl), antimikrobiyal özelliği ve organik doku çözme kapasitesi nedeniyle endodontide en yaygın kullanılan irrigasyon solüsyonudur. Ancak tek başına kullanıldığında inorganik dokunun kanallardan uzaklaştırılmasında yeterli olmamaktadır. Antisepsiyi güçlendirmek ve yaygın kullanılan solüsyonların kısıtlamalarının önüne geçmek amacıyla ideal bir irrigasyon protokolü olarak NaOCl’nin şelasyon ajanlarıyla birlikte kullanılması önerilir. Ancak bu protokol uzun bir klinik zaman gerektirir. Üstelik NaOCI ile bazı şelasyon ajanlarının birlikte kullanılmasının dentinin mineral ve organik içeriğinde değişikliklere, erozyona ve dentin mikrosertliğinde azalmaya neden olabildiği de bilinmektedir. Hem şelasyon ajanı görevi gören hem de antimikrobiyal etkiye sahip bir irrigasyon solüsyonunun kullanılması endodontide iyi bir alternatif olabilir ve tedavi sırasında zaman kazandırabilir. Perasetik asit (PAA), antimikrobiyal etkinliği ve smear tabakasını uzaklaştırma özelliği sayesinde alternatif bir irrigasyon solüsyonu olmaya adaydır. Bu derleme PAA’nın endodonti pratiğindeki etkinliğini ve uygulanabilirliğini araştıran çalışmaları inceleyerek, bu irrigasyon solüsyonunun özelliklerini sunmayı amaçlamaktadır.

Keywords

Kök kanal tedavisi , Perasetik asit , Şelatör ajanlar

Ethical Statement

Yukarıda bilgileri yer alan çalışmanın, etik kurul izni gerektirmeyen çalışmalar arasında yer aldığını beyan ederim.

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