Chlorpropamide Poisoning Induced Atrio-Ventricular Block and Sino-Atrial Block

Year 1991, Volume: 7 Issue: 3-4, 139 - 142, 31.08.1991

Metin Caner

https://izlik.org/JA25CC85HB

Abstract

A 28 year-old man was admitted to the emergency department of our hospital because of attempted suicide with 10 g chlorpropamide (forty tablets of Diabinese). lIe was in profound hypoglycemia and his
ECG revealed complete A.V. block changed to high grade, second and finally first degree A.Y. block. After 48 hours of his drug ingestion ECG turned to normaL In the literature we have found two case reports
in relation to this subject. One of them had bigeminal atrial premature beats and atrial flutter-fibrillation after the ingestion of 2500 mg of chlorpropamide. The other case was about frequent ventricular premature beats during a tolbutamidee test. We haven't found any case report about chlorpropamide induccd A.Y. block and S.A. block in the literature. In conclusion we think that it can be of great help to bear in mind chlorpropamide poisoning can induce A.Y. block.

Keywords

Suicide , Chlorpropamide poisoning , ECG findings , Atria , Sino

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