Kapiller Elektroforez Teknolojisinin Klinik ve Adli Amaçlı DNA Analizlerinde Kullanımı: Geleneksel jel elektroforez yöntemi ile karşılaştırma

Year 2002, Volume: 16 Issue: 2-4, 66 - 71, 31.08.2002

Faruk Aşıcıoğlu

https://izlik.org/JA88BW53PG

Abstract

Kapiller elektroJorez son on Yllda genetik, mikrobiyoloji, biyokimya. klinik ve adli tip gibi bir fok alanda protein. ila~'; nilkleik as it vb. molekullerin aymmmda etkin ve ekonomik bir yontem olarak geni§ kullamm alam bulmu§tur. Son Ylliarda kapiller elektroJorez'in UV-VIS absorbans, LlF( lazer destekli floresans}. kitle spektrometri gibi cihazlarla kombine edilmesi sonucunda daha hassas ve daha hlZlz aymm imkam dogmu§tur. Yazlmlzda kapiller elektroforez teknolojisinin dayandlgl prensipler, geli§im sureci gunumuzdeki uygulama alanlan ve ozellikle DNA analizindeki onemi derlenerek yontemin geleneksel jel elektroforez yontemiyle kar§lla§tmlmasl amaflanml§tlr.

Keywords

Adli amaçlı DNA analizi , Kapiller Elektroforez , Geleneksel jel elektroforez

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