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Xerostomia

Yıl 2011, Cilt: 5 Sayı: 1, 804 - 809, 01.04.2011

Öz

Saliva plays an important role in oral health. Xerostomia is defined as the subjective perception of dry mouth. Xerostomia is generally defined as an unstimulated whole saliva flow rate of less than 0,1-0,2 ml/min and a stimulated whole saliva flow rate of less than 0,7 ml. Drugs are the most common cause. Disease of salivary glands can also cause salivary dysfunction. Dehydration, as in diabetes mellitus an occasional cause of xerostomia. Oral complications are dental caries, candidiasis, taste changes in xerostomia. Salivary substitues may help symptomatically. Salivation may be promoted by using stimulant: chewing gums, colinerjic drugs that stimulate salivation, such as pilokarpin. The aim of this article reviews the cause of xerostomia and treatments

Kaynakça

  • Grupta A., Epstein J.B., Sroussi H. Hyposalivation in elderly patients. J Can Dent Assoc. 72: 841- 846, 2006.
  • Astor F.C., Hanft K.L., Ciocon J.O. Xerostomia: A prevalent condition in the elderly. Ear Nose Throat J.78: 476-479, 1999.
  • Canay Ş, Çiftçi Y. Yaşlı bireylerde sistemik hastalıklarla birlikte izlenen ağız bulguları. Geriatri. 6: 104-108, 2003.
  • Ship J.A., Pillemer S.R., Baum B.J. Xerostomia in the geriatric patient. J Am Geriatr Soc. 50: 535-543, 2002.
  • Nederfors T., Isaksson R., Mornstad H., Dahlof C. Prevalence of perceived symptoms of dry mouth in an adult Swedish population –relation to age, sex and pharmacotherapy. Community Dent Oral Epidemiol. 25: 211-216, 1997.
  • Thomson W.M., Lawrence H.P., Broadbent J.M. Poulton R. The impact of xerostomia on oral health- reated quality of life among younger adults. Health Qual Life Outcomes. 4: 86-92, 2006.
  • Narhi T.O. Prevalence of subjective feelings of dry mouth in the elderly. J Dent Res. 73: 20-25, 1994.
  • Fox P.C., Van der Van P.F., Sonies B.C. Xerostomia:evaluation of a symptom with increasing significance. JADA. 110: 519-525, 1985.
  • Navazesh M., Brıghtman V.J., Pogoda J.M. Relationship of medical status, medications, and salivary flow rates in adults of different ages. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 81: 172-176, 1996.
  • Thomson W.M., Chalmers J.M., Spencer A.J., Slade G.D., Carter K.D. A longitudinal study of medication exposure and xerostomia among older people. Gerodontology. 23: 205-213, 2006.
  • Cassolato S.F., Turnbull R.S. Xerostomia: Clinical aspects and treatment. Gerodontology. 20: 64- 77, 2003.
  • Demiralp B., Güncü G.N., Yamalık N., Hatipoğlu H., Karabulut E., Alpar R., Nazlıel-Elverdi H. Ağız Kuruluğu olan bireylerdeki dişeti nemliliği. Türk geriatri derg. 14:111-116,2011
  • Rhodus N.L., Johnson D.K. The prevalance of oral manifestations of systemic lupus erythematosus. Quintessence Int. 21: 461-465,1990.
  • Reynosa-Paz S., Leung P.S., Van De Water J., Tanaka A., Munoz S., Bass N. Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis. Hepatology 31:24-29, 2000.
  • Mang F.W., Michieletti P., O’Rourke K., Cauch –Dudek K., Diamant N., Bookman A., Primary biliary cirrhosis, sicca complex, and dysphagia. Dysphagia 12:167-170, 1997.
  • Porter S.R., Scully C., Hegarty A.M. An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97: 28-46, 2004.
  • Scully C. Oral and Maxillofacial Medicine. Ediburgh:Elsevier Limited,2004, 98-107.
  • Fox P.C., Busch K.A., Baum B.J. Subjective reports of xerostomia and objective measures of salivary gland preformance. JADA. 115: 581-584, 1987.
  • Hopcraft M.S., Tan C. Xerostomia: an update for clinicans. ADA. 55: 238-244, 2010.
  • Navazesh M, Chrıstensen C.M.A. Comparison of whole mouth resting and stımulated salivary measurement procedures. J Dent Res. 61: 1158- 1162, 1982.
  • Lee S.K., Lee S.W., Chung S.C. Analysis of residual saliva and minor salivary gland secretions in patients with dry mouth. Arch Oral Biol. 47: 637-641, 2002.
  • Disabota-Mordaski T., Kleinberg I. Measurement and comparison of the residual saliva on various oral mucosal and dentition surfaces in humans. Arch Oral Biol. 41: 655-665, 1996.
  • Kakinoki Y., Nishihara T., Arita M., Shibuya K., Ishikawa M. Usefulness of new wetness tester for diagnosis of dry mouth in disabled patients. Gerodontology. 21: 229-231, 2004.
  • Ogami K., Sakurai K., Ando T. A method of mesuring saliwary flow rate in the lower labial mucosal region. J Oral Rehabil. 31: 861-865, 2004.
  • Guggenheimer J., Moore P.A. Xerostomia. JADA. 134: 61-69, 2003.
  • Fox P.C. Management of dry mouth. Dent Clin North Am. 41: 863-875, 1997.
  • Alpöz E., Karavana S.Y., Güneri P, Baloğlu E., Boyacıoğlu H. Ağız içi nemlendirici özelliği olan iki jelin (Oral Balance ve Bioxtra) viskosite özelliklerinin değerlendirilmesi. Atatürk Üniv. Diş. Hek. Fak. Derg. 17:29-34,2007.
  • Brennan M.T., Shariff G., Lochart P.B., Fox P.C. Treatment of xerostomia: a systematic review of therapeutic trials. Dent Clin North Am. 46: 847- 856, 2002.
  • Fox P.C., Atkinson J.C., Macynski A.A. Pilocarpine treatment of salivary gland hypofunction and dry mouth(xerostomia). Arch Intern Med. 151: 1149- 52, 1991.
  • Gornitsky M., Shenouda G., Sultanem K., Katz H., Hier M., Black M., Velly AN..Double- blind randomized, placebo-controlled study of pilocarpine to salvage salivary gland function during radiotherapy of patients with head and neck cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 98: 45-52, 2004.
  • Braga F.P.F., Junior C.A.L., Alves F.A.A., Migliari D.A. Acupuncture fort he prevention of radiation induced xerostomia in patients with head and neck cancer. Braz Oral Res. 25: 2-6, 2011.
  • Khurshudian AV. A pilot study to test the efficacy of oral administration of interferon-alpha lozenges to patients with Sjogren’s syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 95: 38-44, 2003.

Ağız Kuruluğu

Yıl 2011, Cilt: 5 Sayı: 1, 804 - 809, 01.04.2011

Öz

Ağız sağlığında tükürük önemli bir rol oynar. Xerostomia ağız kuruluğunun subjektif olarak algılanması olarak tanımlanır. Ağız kuruluğu genellikle uyarılmamış total tükürük akış hızı dakikada 0,1 ml den , uyarılmış total tükürük akış hızıda dakikada 0,7 ml den az olmasıyla tanımlanır. İlaçlar en yaygın nedenidirler. Tükürük bezleri hastalıkları tükürük fonksiyon bozukluklarına neden olabilir. Diabetes mellitusda, dehidrasyon bazen xerostomia nedenidir. Xerostomiadaki ağız komplikasyonları diş çürükleri, candidalar ve tat değişiklikleridir. Yapay tükürük semptomatik olarak yardımcı olabilir. Tükürük salgılaması uyarıcılar kullanılarak arttırılabilir: sakızlar, tükürük uyaran kolinerjik ilaçlar, örneğin pilokarpin. Bu çalışmanın amacı ağız kuruluğunun nedenlerini ve tedavisini değerlendirmektir

Kaynakça

  • Grupta A., Epstein J.B., Sroussi H. Hyposalivation in elderly patients. J Can Dent Assoc. 72: 841- 846, 2006.
  • Astor F.C., Hanft K.L., Ciocon J.O. Xerostomia: A prevalent condition in the elderly. Ear Nose Throat J.78: 476-479, 1999.
  • Canay Ş, Çiftçi Y. Yaşlı bireylerde sistemik hastalıklarla birlikte izlenen ağız bulguları. Geriatri. 6: 104-108, 2003.
  • Ship J.A., Pillemer S.R., Baum B.J. Xerostomia in the geriatric patient. J Am Geriatr Soc. 50: 535-543, 2002.
  • Nederfors T., Isaksson R., Mornstad H., Dahlof C. Prevalence of perceived symptoms of dry mouth in an adult Swedish population –relation to age, sex and pharmacotherapy. Community Dent Oral Epidemiol. 25: 211-216, 1997.
  • Thomson W.M., Lawrence H.P., Broadbent J.M. Poulton R. The impact of xerostomia on oral health- reated quality of life among younger adults. Health Qual Life Outcomes. 4: 86-92, 2006.
  • Narhi T.O. Prevalence of subjective feelings of dry mouth in the elderly. J Dent Res. 73: 20-25, 1994.
  • Fox P.C., Van der Van P.F., Sonies B.C. Xerostomia:evaluation of a symptom with increasing significance. JADA. 110: 519-525, 1985.
  • Navazesh M., Brıghtman V.J., Pogoda J.M. Relationship of medical status, medications, and salivary flow rates in adults of different ages. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 81: 172-176, 1996.
  • Thomson W.M., Chalmers J.M., Spencer A.J., Slade G.D., Carter K.D. A longitudinal study of medication exposure and xerostomia among older people. Gerodontology. 23: 205-213, 2006.
  • Cassolato S.F., Turnbull R.S. Xerostomia: Clinical aspects and treatment. Gerodontology. 20: 64- 77, 2003.
  • Demiralp B., Güncü G.N., Yamalık N., Hatipoğlu H., Karabulut E., Alpar R., Nazlıel-Elverdi H. Ağız Kuruluğu olan bireylerdeki dişeti nemliliği. Türk geriatri derg. 14:111-116,2011
  • Rhodus N.L., Johnson D.K. The prevalance of oral manifestations of systemic lupus erythematosus. Quintessence Int. 21: 461-465,1990.
  • Reynosa-Paz S., Leung P.S., Van De Water J., Tanaka A., Munoz S., Bass N. Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis. Hepatology 31:24-29, 2000.
  • Mang F.W., Michieletti P., O’Rourke K., Cauch –Dudek K., Diamant N., Bookman A., Primary biliary cirrhosis, sicca complex, and dysphagia. Dysphagia 12:167-170, 1997.
  • Porter S.R., Scully C., Hegarty A.M. An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97: 28-46, 2004.
  • Scully C. Oral and Maxillofacial Medicine. Ediburgh:Elsevier Limited,2004, 98-107.
  • Fox P.C., Busch K.A., Baum B.J. Subjective reports of xerostomia and objective measures of salivary gland preformance. JADA. 115: 581-584, 1987.
  • Hopcraft M.S., Tan C. Xerostomia: an update for clinicans. ADA. 55: 238-244, 2010.
  • Navazesh M, Chrıstensen C.M.A. Comparison of whole mouth resting and stımulated salivary measurement procedures. J Dent Res. 61: 1158- 1162, 1982.
  • Lee S.K., Lee S.W., Chung S.C. Analysis of residual saliva and minor salivary gland secretions in patients with dry mouth. Arch Oral Biol. 47: 637-641, 2002.
  • Disabota-Mordaski T., Kleinberg I. Measurement and comparison of the residual saliva on various oral mucosal and dentition surfaces in humans. Arch Oral Biol. 41: 655-665, 1996.
  • Kakinoki Y., Nishihara T., Arita M., Shibuya K., Ishikawa M. Usefulness of new wetness tester for diagnosis of dry mouth in disabled patients. Gerodontology. 21: 229-231, 2004.
  • Ogami K., Sakurai K., Ando T. A method of mesuring saliwary flow rate in the lower labial mucosal region. J Oral Rehabil. 31: 861-865, 2004.
  • Guggenheimer J., Moore P.A. Xerostomia. JADA. 134: 61-69, 2003.
  • Fox P.C. Management of dry mouth. Dent Clin North Am. 41: 863-875, 1997.
  • Alpöz E., Karavana S.Y., Güneri P, Baloğlu E., Boyacıoğlu H. Ağız içi nemlendirici özelliği olan iki jelin (Oral Balance ve Bioxtra) viskosite özelliklerinin değerlendirilmesi. Atatürk Üniv. Diş. Hek. Fak. Derg. 17:29-34,2007.
  • Brennan M.T., Shariff G., Lochart P.B., Fox P.C. Treatment of xerostomia: a systematic review of therapeutic trials. Dent Clin North Am. 46: 847- 856, 2002.
  • Fox P.C., Atkinson J.C., Macynski A.A. Pilocarpine treatment of salivary gland hypofunction and dry mouth(xerostomia). Arch Intern Med. 151: 1149- 52, 1991.
  • Gornitsky M., Shenouda G., Sultanem K., Katz H., Hier M., Black M., Velly AN..Double- blind randomized, placebo-controlled study of pilocarpine to salvage salivary gland function during radiotherapy of patients with head and neck cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 98: 45-52, 2004.
  • Braga F.P.F., Junior C.A.L., Alves F.A.A., Migliari D.A. Acupuncture fort he prevention of radiation induced xerostomia in patients with head and neck cancer. Braz Oral Res. 25: 2-6, 2011.
  • Khurshudian AV. A pilot study to test the efficacy of oral administration of interferon-alpha lozenges to patients with Sjogren’s syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 95: 38-44, 2003.
Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Research Article
Yazarlar

Şehrazat Evirgen Bu kişi benim

Yayımlanma Tarihi 1 Nisan 2011
Yayımlandığı Sayı Yıl 2011 Cilt: 5 Sayı: 1

Kaynak Göster

Vancouver Evirgen Ş. Ağız Kuruluğu. ADO Klinik Bilimler Dergisi. 2011;5(1):804-9.