Research Article
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Year 2022, , 21 - 29, 28.12.2022
https://doi.org/10.53913/aduveterinary.1183548

Abstract

Project Number

Project No. VTF-150037

References

  • 1.Agarwal, A., Makker, K., & Sharma, R. (2008). Clinical relevance of oxidative stress in male factor infertility: an update. American Journal of Reproductive Immunology, 59(1), 2-11. https://doi.org/10.1111/j.1600-0897.2007.00559.x
  • 2.Amraoui, W., Adjabi, N., Bououza, F., Boumendjel, M., Taibi, F., Boumendjel, A., Abdennour, C., & Messarah, M. (2018). Modulatory Role of Selenium and Vitamin E, Natural Antioxidants, against Bisphenol A-induced Oxidative Stress in Wistar Albinos Rats. Toxicological Research, 34(3), 231-239. https://doi.org/10.5487/TR.2018.34.3.231.
  • 3.Bağış, M. (2013). Kronik alkolik sıçanlarda oluşan testis hasarı üzerine chrysin’nin koruyucu etkisinin histolojik olarak incelenmesi. PhD, University of Osman Gazi, Eskişehir, Türkiye,
  • 4.Conover, W.J. (1980). Practical nonparametric statistics (2nd ed.), Wiley and Sons, Newyork,. p. 229-239.
  • 5.Eladak, S., Moison, D., Guerquin, M.J., Matilionyte, G., Kilcoyne, K., N'Tumba-Byn, T., Messiaen, S., Deceuninck, Y., Pozzi-Gaudin, S., Benachi, A., Livera, G., Antignac, JP., Mitchell, R., Rouiller-Fabre, V., & Habert, R. (2018). Effects of environmental Bisphenol A exposures on germ cell development and Leydig cell function in the human fetal testis. PLoS One, 13(1):e01911934. https://doi.org/10.1371/journal.pone.0191934.

The Effect of Vitamin E on Testicular Histology and Antioxidant Level in Rats Exposed to Bisphenol A

Year 2022, , 21 - 29, 28.12.2022
https://doi.org/10.53913/aduveterinary.1183548

Abstract

This study, it was aimed to investigate the effect of Vitamin E on testicular tissue and antioxidant levels in rats exposed to Bisphenol A. It was determined that the general histological appearances were similar in the control and sham groups, there was a decrease in tubule diameter in the BPA-treated group, but the seminiferous tubular epithelial layer increased. Epithelial shedding and subbasal vacuoles were detected in some tubules in the vitamin E group. Undifferentiated Embryonic Cell Transcription Factor 1 (UTF-1) positive tubule and cell counts were found to be quite high in the BPA group. The antioxidant parameter SOD value was found to be low in the BPA group and higher in the Vitamin E group. It was noted that the MDA value was higher in the BPA-applied group compared to the other groups. At the end of the study, it was determined that vitamin E applied against BPA exposure had positive effects on testicular histology and antioxidant levels in testicular tissue.

Supporting Institution

The current work was financially supported by the Scientific Research Projects of Aydin Adnan Menderes University, .

Project Number

Project No. VTF-150037

Thanks

The authors would like to acknowledge Prof. Dr. Murat Boyacioglu, Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Aydin Adnan Menderes University, for the evaluation of the oxidant-antioxidant parameters.

References

  • 1.Agarwal, A., Makker, K., & Sharma, R. (2008). Clinical relevance of oxidative stress in male factor infertility: an update. American Journal of Reproductive Immunology, 59(1), 2-11. https://doi.org/10.1111/j.1600-0897.2007.00559.x
  • 2.Amraoui, W., Adjabi, N., Bououza, F., Boumendjel, M., Taibi, F., Boumendjel, A., Abdennour, C., & Messarah, M. (2018). Modulatory Role of Selenium and Vitamin E, Natural Antioxidants, against Bisphenol A-induced Oxidative Stress in Wistar Albinos Rats. Toxicological Research, 34(3), 231-239. https://doi.org/10.5487/TR.2018.34.3.231.
  • 3.Bağış, M. (2013). Kronik alkolik sıçanlarda oluşan testis hasarı üzerine chrysin’nin koruyucu etkisinin histolojik olarak incelenmesi. PhD, University of Osman Gazi, Eskişehir, Türkiye,
  • 4.Conover, W.J. (1980). Practical nonparametric statistics (2nd ed.), Wiley and Sons, Newyork,. p. 229-239.
  • 5.Eladak, S., Moison, D., Guerquin, M.J., Matilionyte, G., Kilcoyne, K., N'Tumba-Byn, T., Messiaen, S., Deceuninck, Y., Pozzi-Gaudin, S., Benachi, A., Livera, G., Antignac, JP., Mitchell, R., Rouiller-Fabre, V., & Habert, R. (2018). Effects of environmental Bisphenol A exposures on germ cell development and Leydig cell function in the human fetal testis. PLoS One, 13(1):e01911934. https://doi.org/10.1371/journal.pone.0191934.
There are 5 citations in total.

Details

Primary Language English
Subjects Veterinary Sciences
Journal Section Research Article
Authors

Ayşe Büşra Akbaş 0000-0001-7166-4363

Şadiye Kum 0000-0001-6586-4596

Project Number Project No. VTF-150037
Publication Date December 28, 2022
Submission Date October 3, 2022
Published in Issue Year 2022

Cite

APA Akbaş, A. B., & Kum, Ş. (2022). The Effect of Vitamin E on Testicular Histology and Antioxidant Level in Rats Exposed to Bisphenol A. Animal Health Production and Hygiene, 11(2), 21-29. https://doi.org/10.53913/aduveterinary.1183548