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Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry

Year 2015, Volume: 5 Issue: 2, 120 - 131, 30.12.2015

Murat Metli Yasin Yakar , Yener Tekeli

Abstract

In this study, 0,5 kg of chicken liver sample was taken from 34 different markets in Antakya. The samples were analysed by LC-MS/MS in terms of 38 antibiotic residues from 7 groups. Only in one sample, Trimethoprim (298.5 μg/kg) and Sulfametoxazole (312.8 μg/kg ) residue was detected. Both antibiotic residue amounts are above the limits announced in Turkey and EU regulations. Therefore antibiotic residue analyses should be performed within a plan and efficiently in terms of public health.

Keywords

Chicken liver antibiotic liquid chromatography tandem mass spectrometry

References

  • D. K. Matabudul, B. Conway, I. Lumley, S. Sumar, Food Chemistry, 2001, 75, 345-354.
  • A. M. Shareef, Z. T. Jamel, K. M. Yonis, Iraq Journal of Veterinary Sciences, 2009, 23, 45-48. 131
  • S. Bogialli, R. Curini, A. D. Corcia, A. Lagana, G. Rizzuti, J Agric Food Chem, 2006, 54, 1564-1570.
  • K. Granelli, C. Elgerud, A. Lundström, A. Ohlsson, P. Sjöberg, Anal Chim Acta, 2009, 637, 87-91.
  • J. Chico, A. Rubies, F. Centrich, R. Companyo, M. D. Prat, Journal of Chromatography A, 2008, 1213, 189-199.
  • Commission Regulation (EC) No 37/2010: On pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Official Journal of the European Union, 2009, L 15, 1-72.
  • Türk Gıda Kodeksi: Hayvansal gıdalarda bulunabilecek farmakolojik aktif maddelerin sınıflandırılması ve maksimum kalıntı limitleri yönetmeliği. T.C. Resmi Gazete, Sayı: 28282, 2012.
  • F. Cetinkaya, A. Yibar, G. E. Soyutemiz, B. Okutan, A. Ozcan, M. Y. Karaca, Food Addit Contam Part B Surveill, 2012, 5 (1), 45-49.
  • B. Er, F. K. Onurdag, B. Demirhan, S. O. Özgacar, A. B. Öktem, U. Abbasoğlu, Poultry Science, 2013, 92, 2212-2215.
  • C. K. Cheong, P. Hajeb, S. Jinap, M. R. Ismail-Fitry, International Food Research Journal, 2010, 17, 885-892.
  • E. Kim, K. Bahn, E. Kang, M. Kim, Food Chemistry, 2012, 132, 1063-1070.
  • R. P. Lopes, R. C. Reyes, R. Romero-González, A. G. Frenich, J. L. M. Vidal, Talanta, 2012, 89, 201-208.
  • M. S. Al-Ghamdi, Z. H. Al-Mustafa, F. El-Morsy, A. Al-Faky, I. Haider, H. Essa, Public Health, 2000, 114, 300-304.
  • F. Nizamlıoglu, H. Aydın, Eurasian J Vet Sci, 2012, 28 (3), 154-158.

Likit Kromatografi Tandem Mass Spektrometri ile Tavuk Ciğerinde Antibiyotik Kalıntılarının Belirlenmesi

Year 2015, Volume: 5 Issue: 2, 120 - 131, 30.12.2015

Murat Metli Yasin Yakar , Yener Tekeli

Abstract

Bu çalışmada, Antakya’da 34 farklı tavuk marketinden 0,5 kg alınan tavuk ciğeri
numunesinde antibiyotik kalıntısı araştırılmıştır. Numuneler, 7 grupta toplam 38 antibiyotik
kalıntısı bakımından LC-MS/MS ile analiz edilmiştir. Sadece bir numunede Trimetoprim
(298.5 µg/kg) ve Sulfametoxazole (312.8 µg/kg ) kalıntısı tespit edilmiştir. Her iki antibiyotik
kalıntı miktarı da Türkiye ve Avrupa Birliği mevzuatında bildirilen yasal limitlerin üzerinde
121
olduğu fark edilmiştir. Bu nedenle halk sağlığı açısından hayvansal ürünlerde antibiyotik
kalıntı analizleri bir plan dahilinde ve etkin bir şekilde yapılmalıdır.

Keywords

Tavuk ciğeri antibiyotik likit kromatografi tandem mass spektrometri

References

  • D. K. Matabudul, B. Conway, I. Lumley, S. Sumar, Food Chemistry, 2001, 75, 345-354.
  • A. M. Shareef, Z. T. Jamel, K. M. Yonis, Iraq Journal of Veterinary Sciences, 2009, 23, 45-48. 131
  • S. Bogialli, R. Curini, A. D. Corcia, A. Lagana, G. Rizzuti, J Agric Food Chem, 2006, 54, 1564-1570.
  • K. Granelli, C. Elgerud, A. Lundström, A. Ohlsson, P. Sjöberg, Anal Chim Acta, 2009, 637, 87-91.
  • J. Chico, A. Rubies, F. Centrich, R. Companyo, M. D. Prat, Journal of Chromatography A, 2008, 1213, 189-199.
  • Commission Regulation (EC) No 37/2010: On pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Official Journal of the European Union, 2009, L 15, 1-72.
  • Türk Gıda Kodeksi: Hayvansal gıdalarda bulunabilecek farmakolojik aktif maddelerin sınıflandırılması ve maksimum kalıntı limitleri yönetmeliği. T.C. Resmi Gazete, Sayı: 28282, 2012.
  • F. Cetinkaya, A. Yibar, G. E. Soyutemiz, B. Okutan, A. Ozcan, M. Y. Karaca, Food Addit Contam Part B Surveill, 2012, 5 (1), 45-49.
  • B. Er, F. K. Onurdag, B. Demirhan, S. O. Özgacar, A. B. Öktem, U. Abbasoğlu, Poultry Science, 2013, 92, 2212-2215.
  • C. K. Cheong, P. Hajeb, S. Jinap, M. R. Ismail-Fitry, International Food Research Journal, 2010, 17, 885-892.
  • E. Kim, K. Bahn, E. Kang, M. Kim, Food Chemistry, 2012, 132, 1063-1070.
  • R. P. Lopes, R. C. Reyes, R. Romero-González, A. G. Frenich, J. L. M. Vidal, Talanta, 2012, 89, 201-208.
  • M. S. Al-Ghamdi, Z. H. Al-Mustafa, F. El-Morsy, A. Al-Faky, I. Haider, H. Essa, Public Health, 2000, 114, 300-304.
  • F. Nizamlıoglu, H. Aydın, Eurasian J Vet Sci, 2012, 28 (3), 154-158.
There are 14 citations in total.

Details

Subjects Engineering
Journal Section Biology
Authors

Murat Metli This is me

Yasin Yakar

Yener Tekeli This is me

Publication Date December 30, 2015
Submission Date January 25, 2016
Published in Issue Year 2015 Volume: 5 Issue: 2

Cite

APA Metli, M., Yakar, Y., & Tekeli, Y. (2015). Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry. Adıyaman University Journal of Science, 5(2), 120-131.
AMA Metli M, Yakar Y, Tekeli Y. Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry. ADYU J SCI. December 2015;5(2):120-131.
Chicago Metli, Murat, Yasin Yakar, and Yener Tekeli. “Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry”. Adıyaman University Journal of Science 5, no. 2 (December 2015): 120-31.
EndNote Metli M, Yakar Y, Tekeli Y (December 1, 2015) Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry. Adıyaman University Journal of Science 5 2 120–131.
IEEE M. Metli, Y. Yakar, and Y. Tekeli, “Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry”, ADYU J SCI, vol. 5, no. 2, pp. 120–131, 2015.
ISNAD Metli, Murat et al. “Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry”. Adıyaman University Journal of Science 5/2 (December 2015), 120-131.
JAMA Metli M, Yakar Y, Tekeli Y. Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry. ADYU J SCI. 2015;5:120–131.
MLA Metli, Murat et al. “Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry”. Adıyaman University Journal of Science, vol. 5, no. 2, 2015, pp. 120-31.
Vancouver Metli M, Yakar Y, Tekeli Y. Determination of Antibiotic Residues in Chicken Liver by Liquid Chromatography-Tandem Mass Spectrometry. ADYU J SCI. 2015;5(2):120-31.

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