A CASE WITH FOX-FORDYCE DISEASE STARTING AT POSTMONEPAUSAL STAGE

Abstract

Fox-Fordyce is an uncommon,sporadic disease that occurs because of the blockage and intraepidermal rupture of the apocrine ducts.It is characterised with pruritic, follicular papules. In this disease the most effected areas are pubic and axillary regions. The etiology of the disease is unknown. Postpubertal and premenopausal women are at high risk. There is no effective treatment so several palliative methods are being tried. In this article, a 64 years old, postmenopausal case, whose Fox-Fordyce disease is clinically proven is presented because of it’s rare occurrence

Keywords

• Fox-Fordyce disease,apocrine gland,isotretinoin treatment,postmenapausal stage

POSTMENAPOZAL BAŞLANGIÇLI BİR FOX-FORDYCE HASTALIĞI OLGUSU

Abstract

Fox-Fordyce hastalığı, apokrin kanalın tıkanması ve intraepidermal rüptürü nedeniyle oluşan, kaşıntılı folliküler papüllerle karakterize, sporadik, nadir görülen bir hastalıktır. Etiyolojisi bilinmeyen hastalıkta aksilla ve pubik bölgeler en sık tutulmaktadır. Postpübertal ve premenapozal kadınlar risk altındadır. Etkin bir tedavisi olmadığından, hastaları rahatlatmaya yönelik çeşitli tedaviler denenmektedir. Bu yazıda literatürde nadir rastlanan postmenapozal dönemde başlayan, 64 yaşında klinik olarak Fox-Fordyce tanısı koyduğumuz bir olgu sunulmuştur

Keywords

• Fox-Fordyce Hastalığı,apokrin bez,izotretinoin tedavisi,postmenapozal dönem

References

1. 1)Fitzpatrick TB., Freedberg IM., Austen KF., Wolff K. FoxFordyce Diseases. In: Dermatology in General Medicine. 4.th. ed. New York: Mc Graw Hill Co; 1993. Vol. 1.p.1758-761.
2. 2)Hurley H. J. Diseases of the Apocrine Sweat Glands,. In: Moshella and Hurley: Dermatology. Philadelphia, Saunders Company. 3rd. ed. 1992. Vol 2.p.1503-1506.
3. 3)Alpay K., Bahadır S., Yıldız K, et al. Bir Fox-fordyce olgusu. Türkderm. 1994; 28: 115-116.
4. 4)Karagülle Ş, Kiremitçi Ü. Fox-Fordyce Hastalığı. İstanbul tıp Dergisi. 1998; 1: 50-52.
5. 5)Tükenmez Demirci G, Yaşar Ş, Mansur T, Esen Aydıngöz İ,Sever S. Prepübertal Fox-Fordyce Disease: A Case Report. Türkiye Klinikleri J Med Sci. 2006; 26: 338-41.
6. 6)Erkek E, Koçak M, Atasoy P, Birol A, Bozdoğan Ö. Fox-Fordyce Hastalığı. TÜRKDERM. 2002; 36: 60-63.
7. 7)Odom RB, James WC, Berger TG. Andrews’diseases of the skin. Clinical Dermatology. Philadelphia, USA: W.B. Saunders Company, 2000.p.249.
8. 8)Effendy I, Ossowski B, Happle R. Fox-Fordyce disease in a male patient-response to oral retinoid treatment. Clin Exp Dermatol. 1994; 19: 67-9.

9. 9)Ranaletta M, Rositto A, Drut R. Fox-Fordyce disease in two prepubertal girls: histopatolojik demonstration of ecrine sweat gland involvement. Pediatr Dermatol. 1996; 13: 294-7.
10. 10)Tkach JR. Tretinoin treatment of Fox-Fordyce disease. Arch Dermatol. 1979; 115: 1285.
11. 11)Miller ML,harford RR, Yeager JK. Fox-Fordyce disease trested with clindamycin soution. Arch Dermatol. 1995; 131: 1112-3.
12. 12)Feldmann R, Masouye I, Chavaz P, Saurat JH. Fox-Fordyce disease in two prepubertal girls: histopatolojic demontration of ecrine sweat gland involvement. Pediatr Dermatol. 1996; 13: 294-7.
13. 13) Giacobetti R, Caro WA, Roenigk HH. Fox-Fordyce disease. Control with tretinoin cream. Arch dermatol. 1979; 115: 1365-6.
14. 14) Monk BE. Fox-Fordyce disease in amale patient-response to oral retinoid treatment. Br J Dermatol. 1993; 129: 355