Case Report
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Herpes Simplex Enfeksiyonuna Bağlı Olarak Gelişen Eritema Multiforme Olgusu

Year 2019, Volume: 52 Issue: 1, 87 - 89, 14.03.2019

Abstract

Eritema multiforme(EM);
karakateristik hedef benzeri cilt lezyonlarının var olduğu, mukozal tutulumun
eşlik edebildiği, nadiren tekrar edebilen, birçok etkinin sebep olabileceği
akut bir hastalıktır. Bu yazıda  perioral
bölgedeki herpes enfeksiyonuna ikincil olarak gelişen eritema multiforme olgusu
sunuldu. Olgunun kontrol fizik muayenesinde lezyonların valasiklovir tedavisine
iyi yanıt verdiği gözlendi. Lezyonlarda tekrarlama gözlenmedi. Sonuç olarak
nadir görülen EM hastalığında literatürde de en çok etken olarak tanımlanan
herpes enfeksiyonu öncelikli sebep olarak düşünülmelidir.

References

  • 1.Huff JC, Weston WL, Tonnesen MG. Erythema multiforme: a critical review of characteristics, diagnostic criteria, and causes. J Am Acad Dermatol 1983; 8:763.
  • 2.Huff JC. Erythema multiforme. Dermatol Clin 1985; 3:141.
  • 3.French LE, Prins C. Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis. In: Dermatology, Bolognia JL, Jorizzo JL, Rapini RP (Eds), Elsevier Limited, 2008. p.287.
  • 4.Weston WL, Brice SL, Jester JD, et al. Herpes simplex virus in childhood erythema multiforme. Pediatrics 1992; 89:32.
  • 5.Weston WL. Herpes-associated erythema multiforme. J Invest Dermatol 2005; 124:xv.
  • 6.Schalock PC, Dinulos JG, Pace N, et al. Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Pediatr Dermatol 2006; 23:546.
  • 7.Roujeau JC. Erythema multiforme. In: Fitzpatrick's Dermatology in General Medicine, Wolff K, Goldsmith LA, Katz SI, et al (Eds), McGraw-Hill Companies, Inc, 2008. p.343.
  • 8.Schofield JK, Tatnall FM, Leigh IM. Recurrent erythema multiforme: clinical features and treatment in a large series of patients. Br J Dermatol 1993; 128:542.
  • 9.Wetter DA, Davis MD. Recurrent erythema multiforme: clinical characteristics, etiologic associations, and treatment in a series of 48 patients at Mayo Clinic, 2000 to 2007. J Am Acad Dermatol 2010; 62:45.
  • 10.Farthing PM, Maragou P, Coates M, et al. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med 1995; 24:9.
  • 11.Ayangco L, Rogers RS 3rd. Oral manifestations of erythema multiforme. Dermatol Clin 2003; 21:195.
  • 12.Rogers RS 3rd. Pseudo-Behçet's disease. Dermatol Clin 2003; 21:49.
  • 13.Drago F, Parodi A, Rebora A. Persistent erythema multiforme: report of two new cases and review of literature. J Am Acad Dermatol 1995; 33:366.
  • 14.Pavlović MD, Karadaglić DM, Kandolf LO, Mijusković ZP. Persistent erythema multiforme: a report of three cases. J Eur Acad Dermatol Venereol 2001; 15:54.
  • 15.Chen CW, Tsai TF, Chen YF, Hung CM. Persistent erythema multiforme treated with thalidomide. Am J Clin Dermatol 2008; 9:123.
  • 16.Wanner M, Pol-Rodriguez M, Hinds G, et al. Persistent erythema multiforme and CMV infection. J Drugs Dermatol 2007; 6:333.
  • 17.Al-Johani KA, Fedele S, Porter SR. Erythema multiforme and related disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(5):642-54.
  • 18.Kokuba H, Imafuku S, Huang S, Aurelian L, Burnett JW. Erythema multiforme lesions are associated with expression of a herpes simplex virus (HSV) gene and qualitative alterations in the HSV-specific T-cell response. Br J Dermatol. 1998;138(6):952-64.
  • 19.Fernández García JR, Alcaraz Vera M, Ruiz Jiménez MA, Rodríguez Murillo JM, Hens Pérez A. Eritema multiforme. Rev Esp Pediatr. 2000;56:202- 5. [In Spanish].
  • 20.Ng PP, Sun YJ, Tan HH, Tan SH. Detection of herpes simplex virus genomic DNA in various subsets of Erythema multiforme by polymerase chain reaction. Dermatology. 2003;207(4):349-53.
  • 21.Farthing PM, Maragou P, Coates M, Tatnall F, Leigh IM, Williams DM. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med. 1995;24(1):9-13.
  • 22.Farthing P, Bagan JV, Scully C. Mucosal diseases series. Number IV. Erythema multiforme. Oral Dis. 2005;11(5):261-7.
  • 23.Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y puesta al dia [Erythema multiforme: revision and update]. RCOE. 2004;9(4):415-23. [In Spanish; English abstract].
  • 24.Woo SB, Challacombe SJ. Management of recurrent oral herpes simplex infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(Suppl):S12.e1-18.
Year 2019, Volume: 52 Issue: 1, 87 - 89, 14.03.2019

Abstract

References

  • 1.Huff JC, Weston WL, Tonnesen MG. Erythema multiforme: a critical review of characteristics, diagnostic criteria, and causes. J Am Acad Dermatol 1983; 8:763.
  • 2.Huff JC. Erythema multiforme. Dermatol Clin 1985; 3:141.
  • 3.French LE, Prins C. Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis. In: Dermatology, Bolognia JL, Jorizzo JL, Rapini RP (Eds), Elsevier Limited, 2008. p.287.
  • 4.Weston WL, Brice SL, Jester JD, et al. Herpes simplex virus in childhood erythema multiforme. Pediatrics 1992; 89:32.
  • 5.Weston WL. Herpes-associated erythema multiforme. J Invest Dermatol 2005; 124:xv.
  • 6.Schalock PC, Dinulos JG, Pace N, et al. Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Pediatr Dermatol 2006; 23:546.
  • 7.Roujeau JC. Erythema multiforme. In: Fitzpatrick's Dermatology in General Medicine, Wolff K, Goldsmith LA, Katz SI, et al (Eds), McGraw-Hill Companies, Inc, 2008. p.343.
  • 8.Schofield JK, Tatnall FM, Leigh IM. Recurrent erythema multiforme: clinical features and treatment in a large series of patients. Br J Dermatol 1993; 128:542.
  • 9.Wetter DA, Davis MD. Recurrent erythema multiforme: clinical characteristics, etiologic associations, and treatment in a series of 48 patients at Mayo Clinic, 2000 to 2007. J Am Acad Dermatol 2010; 62:45.
  • 10.Farthing PM, Maragou P, Coates M, et al. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med 1995; 24:9.
  • 11.Ayangco L, Rogers RS 3rd. Oral manifestations of erythema multiforme. Dermatol Clin 2003; 21:195.
  • 12.Rogers RS 3rd. Pseudo-Behçet's disease. Dermatol Clin 2003; 21:49.
  • 13.Drago F, Parodi A, Rebora A. Persistent erythema multiforme: report of two new cases and review of literature. J Am Acad Dermatol 1995; 33:366.
  • 14.Pavlović MD, Karadaglić DM, Kandolf LO, Mijusković ZP. Persistent erythema multiforme: a report of three cases. J Eur Acad Dermatol Venereol 2001; 15:54.
  • 15.Chen CW, Tsai TF, Chen YF, Hung CM. Persistent erythema multiforme treated with thalidomide. Am J Clin Dermatol 2008; 9:123.
  • 16.Wanner M, Pol-Rodriguez M, Hinds G, et al. Persistent erythema multiforme and CMV infection. J Drugs Dermatol 2007; 6:333.
  • 17.Al-Johani KA, Fedele S, Porter SR. Erythema multiforme and related disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(5):642-54.
  • 18.Kokuba H, Imafuku S, Huang S, Aurelian L, Burnett JW. Erythema multiforme lesions are associated with expression of a herpes simplex virus (HSV) gene and qualitative alterations in the HSV-specific T-cell response. Br J Dermatol. 1998;138(6):952-64.
  • 19.Fernández García JR, Alcaraz Vera M, Ruiz Jiménez MA, Rodríguez Murillo JM, Hens Pérez A. Eritema multiforme. Rev Esp Pediatr. 2000;56:202- 5. [In Spanish].
  • 20.Ng PP, Sun YJ, Tan HH, Tan SH. Detection of herpes simplex virus genomic DNA in various subsets of Erythema multiforme by polymerase chain reaction. Dermatology. 2003;207(4):349-53.
  • 21.Farthing PM, Maragou P, Coates M, Tatnall F, Leigh IM, Williams DM. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med. 1995;24(1):9-13.
  • 22.Farthing P, Bagan JV, Scully C. Mucosal diseases series. Number IV. Erythema multiforme. Oral Dis. 2005;11(5):261-7.
  • 23.Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y puesta al dia [Erythema multiforme: revision and update]. RCOE. 2004;9(4):415-23. [In Spanish; English abstract].
  • 24.Woo SB, Challacombe SJ. Management of recurrent oral herpes simplex infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(Suppl):S12.e1-18.
There are 24 citations in total.

Details

Journal Section Case report
Authors

Sevinç Keskin

Publication Date March 14, 2019
Submission Date April 27, 2017
Published in Issue Year 2019 Volume: 52 Issue: 1

Cite

AMA Keskin S. Herpes Simplex Enfeksiyonuna Bağlı Olarak Gelişen Eritema Multiforme Olgusu. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. March 2019;52(1):87-89.