Eritema multiforme(EM);
karakateristik hedef benzeri cilt lezyonlarının var olduğu, mukozal tutulumun
eşlik edebildiği, nadiren tekrar edebilen, birçok etkinin sebep olabileceği
akut bir hastalıktır. Bu yazıda perioral
bölgedeki herpes enfeksiyonuna ikincil olarak gelişen eritema multiforme olgusu
sunuldu. Olgunun kontrol fizik muayenesinde lezyonların valasiklovir tedavisine
iyi yanıt verdiği gözlendi. Lezyonlarda tekrarlama gözlenmedi. Sonuç olarak
nadir görülen EM hastalığında literatürde de en çok etken olarak tanımlanan
herpes enfeksiyonu öncelikli sebep olarak düşünülmelidir.
6.Schalock PC, Dinulos JG, Pace N, et al. Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Pediatr Dermatol 2006; 23:546.
7.Roujeau JC. Erythema multiforme. In: Fitzpatrick's Dermatology in General Medicine, Wolff K, Goldsmith LA, Katz SI, et al (Eds), McGraw-Hill Companies, Inc, 2008. p.343.
8.Schofield JK, Tatnall FM, Leigh IM. Recurrent erythema multiforme: clinical features and treatment in a large series of patients. Br J Dermatol 1993; 128:542.
9.Wetter DA, Davis MD. Recurrent erythema multiforme: clinical characteristics, etiologic associations, and treatment in a series of 48 patients at Mayo Clinic, 2000 to 2007. J Am Acad Dermatol 2010; 62:45.
10.Farthing PM, Maragou P, Coates M, et al. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med 1995; 24:9.
13.Drago F, Parodi A, Rebora A. Persistent erythema multiforme: report of two new cases and review of literature. J Am Acad Dermatol 1995; 33:366.
14.Pavlović MD, Karadaglić DM, Kandolf LO, Mijusković ZP. Persistent erythema multiforme: a report of three cases. J Eur Acad Dermatol Venereol 2001; 15:54.
15.Chen CW, Tsai TF, Chen YF, Hung CM. Persistent erythema multiforme treated with thalidomide. Am J Clin Dermatol 2008; 9:123.
16.Wanner M, Pol-Rodriguez M, Hinds G, et al. Persistent erythema multiforme and CMV infection. J Drugs Dermatol 2007; 6:333.
17.Al-Johani KA, Fedele S, Porter SR. Erythema multiforme and related disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(5):642-54.
18.Kokuba H, Imafuku S, Huang S, Aurelian L, Burnett JW. Erythema multiforme lesions are associated with expression of a herpes simplex virus (HSV) gene and qualitative alterations in the HSV-specific T-cell response. Br J Dermatol. 1998;138(6):952-64.
19.Fernández García JR, Alcaraz Vera M, Ruiz Jiménez MA, Rodríguez Murillo JM, Hens Pérez A. Eritema multiforme. Rev Esp Pediatr. 2000;56:202- 5. [In Spanish].
20.Ng PP, Sun YJ, Tan HH, Tan SH. Detection of herpes simplex virus genomic DNA in various subsets of Erythema multiforme by polymerase chain reaction. Dermatology. 2003;207(4):349-53.
21.Farthing PM, Maragou P, Coates M, Tatnall F, Leigh IM, Williams DM. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med. 1995;24(1):9-13.
22.Farthing P, Bagan JV, Scully C. Mucosal diseases series. Number IV. Erythema multiforme. Oral Dis. 2005;11(5):261-7.
23.Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y puesta al dia [Erythema multiforme: revision and update]. RCOE. 2004;9(4):415-23. [In Spanish; English abstract].
6.Schalock PC, Dinulos JG, Pace N, et al. Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Pediatr Dermatol 2006; 23:546.
7.Roujeau JC. Erythema multiforme. In: Fitzpatrick's Dermatology in General Medicine, Wolff K, Goldsmith LA, Katz SI, et al (Eds), McGraw-Hill Companies, Inc, 2008. p.343.
8.Schofield JK, Tatnall FM, Leigh IM. Recurrent erythema multiforme: clinical features and treatment in a large series of patients. Br J Dermatol 1993; 128:542.
9.Wetter DA, Davis MD. Recurrent erythema multiforme: clinical characteristics, etiologic associations, and treatment in a series of 48 patients at Mayo Clinic, 2000 to 2007. J Am Acad Dermatol 2010; 62:45.
10.Farthing PM, Maragou P, Coates M, et al. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med 1995; 24:9.
13.Drago F, Parodi A, Rebora A. Persistent erythema multiforme: report of two new cases and review of literature. J Am Acad Dermatol 1995; 33:366.
14.Pavlović MD, Karadaglić DM, Kandolf LO, Mijusković ZP. Persistent erythema multiforme: a report of three cases. J Eur Acad Dermatol Venereol 2001; 15:54.
15.Chen CW, Tsai TF, Chen YF, Hung CM. Persistent erythema multiforme treated with thalidomide. Am J Clin Dermatol 2008; 9:123.
16.Wanner M, Pol-Rodriguez M, Hinds G, et al. Persistent erythema multiforme and CMV infection. J Drugs Dermatol 2007; 6:333.
17.Al-Johani KA, Fedele S, Porter SR. Erythema multiforme and related disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(5):642-54.
18.Kokuba H, Imafuku S, Huang S, Aurelian L, Burnett JW. Erythema multiforme lesions are associated with expression of a herpes simplex virus (HSV) gene and qualitative alterations in the HSV-specific T-cell response. Br J Dermatol. 1998;138(6):952-64.
19.Fernández García JR, Alcaraz Vera M, Ruiz Jiménez MA, Rodríguez Murillo JM, Hens Pérez A. Eritema multiforme. Rev Esp Pediatr. 2000;56:202- 5. [In Spanish].
20.Ng PP, Sun YJ, Tan HH, Tan SH. Detection of herpes simplex virus genomic DNA in various subsets of Erythema multiforme by polymerase chain reaction. Dermatology. 2003;207(4):349-53.
21.Farthing PM, Maragou P, Coates M, Tatnall F, Leigh IM, Williams DM. Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme. J Oral Pathol Med. 1995;24(1):9-13.
22.Farthing P, Bagan JV, Scully C. Mucosal diseases series. Number IV. Erythema multiforme. Oral Dis. 2005;11(5):261-7.
23.Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y puesta al dia [Erythema multiforme: revision and update]. RCOE. 2004;9(4):415-23. [In Spanish; English abstract].
Keskin S. Herpes Simplex Enfeksiyonuna Bağlı Olarak Gelişen Eritema Multiforme Olgusu. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. March 2019;52(1):87-89.