RELATIONSHIP BETWEEN ROUTINE INFLAMMATORY MARKERS AND EJECTION FRACTION IN ELDERLY MEN WITH STABLE CORONARY ARTERY DISEASE

Year 2020, Volume: 53 Issue: 3, 165 - 170, 31.12.2020

Ayhan Coşgun

https://doi.org/10.20492/aeahtd.668894

Abstract

Purpose: New inflammatory markers have recently been proposed for chronic inflammatory diseases. Inflammation plays an important role in the pathogenesis of stable coronary artery disease(SCAD). The aim of our study was to evaluate hematological parameters in elderly male patients with SCAD.
Material and Methods: Between March 2015 and August 2019, 131 male patients over 65 years of age who had exertion angina for 3 months and had 3 vascular disease on coronary angiography and had an ejection fraction (EF) of less than 55% on transthoracic echocardiogram were included in the study group 1. A total of 117 male patients over 65 years of age who had exertion angina more than 3 months and 3-vessel disease on coronary angiography and whose EF was above 55% on transthoracic echocardiogram were included in the study. Data of elderly male patients were recorded from the patient files of the institution. The data of the two study groups were compared.
Results: In group 1, Red Cell Distribution Width (RDW), Mean Platelet Volume (MPV)/Platelet (P) and RDW/P values were significantly higher than group 2 (p <.01)
Conclusion: Routine inflammatory markers were higher in elderly men with stable coronary artery disease with low ejection fraction than in normal ejection fractioned.

Thanks

The authors report no conflict of interest.

STABİL KORONER ARTER HASTALIĞI OLAN YAŞLI ERKEKLERDE RUTİN İNFLAMATUAR MARKERLER VE EJEKSİYON FRAKSİYONU ARASINDAKİ İLİŞKİ

Abstract

Amaç: Son zamanlarda kronik inflamatuar hastalıklar için bazı inflamatuar belirteçler önerilmiştir. İnflamasyon, stabil koroner arter hastalığının (SKAH) patogenezinde önemli bir rol oynar. Çalışmamızın amacı, SKAH olan yaşlı erkek hastalarda hematolojik ve biyokimyasal inflamatuvar parametreleri değerlendirmektir.
Yöntemler: Mart 2015 ve Ağustos 2019 tarihleri arasında, 3 ay boyunca efor anjina olan, koroner anjiyografide 3 damar hastalığı olan ve transtorasik ekokardiyogramda ejeksiyon fraksiyonu (EF) %55'den az olan 65 yaş üstü 131 erkek hasta birinci çalışma grubuna dahil edildi. En az 3 aydan fazla efor anjinası olan, koroner anjiografide 3 damar hastalığı tespit edilen ve transtorasik ekokardiyogramda EF% 55'nin üzerinde olan, 65 yaş üstü 117 erkek hasta ikinci çalışma grubuna dahil edildi. Yaşlı erkek hastaların verileri, kurumun hasta dosyalarından kaydedildi. İki çalışma grubunun verileri karşılaştırıldı.
Bulgular: Grup 1' de, Red Cell Distribution Width (RDW), Mean Plattelet Volüm (MPV) / trombosit (P) ve RDW / P değerleri grup 2'den anlamlı olarak yüksekti (p <.01).
Sonuç: Yeni enflamatuar belirteçler düşük ejeksiyon fraksiyonu olan stabil koroner arter hastalığı olan yaşlı erkeklerde normal ejeksiyon fraksiyonu olanlardan daha yüksekti.

Keywords

koroner kalp hastalığı, inflamasyon, yaşlı erkekler, ejeksiyon fraksiyonu

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