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The relationship between the number of patients admitted to the emergency department with acute exacerbation of COPD and certain meteorological parameters

Year 2021, Volume: 54 Issue: 1, 112 - 116, 27.04.2021
https://doi.org/10.20492/aeahtd.884831

Abstract

Amaç: Biz çalışmamızda acil servise bir solunum yolu hastalığı olan KOAH akut alevlenme ile gelen hastaların meterolojik parametrelerden sıcaklık, nem ve hava basınçı etkisiyle hastaneye başvuru sayıları arasındaki ilişkiyi ortaya koymayı amaçladık. Metod: Bu çalışma rektospektif bir çalışmadır.Acil servise KOAH akut alevlenme ile başvuran hastaların atak sıklığını değerlendirmede sıcaklık, hava basıncı ve nem faktörününün etkisini tespit etmek için yapıldı. Hasta grubu Sincan Dr. Nafiz Körez Devlet Hastanesi Acil Servisine 01.01.2017-31.12.2019 tarihleri arasında başvuran hastalardan oluşturuldu. Bu tarihler arasındaki basınç, sıcaklık ve nem oranı değerleri aynı bölgenin meteorolojik verileri kullanılarak belirlendi. Bulgular: Toplamda 1095 gün içinde 1082 gün KOAH atak ile başvuru olmuştur. Günde ortalama 6 KOAH’lı hasta başvurmuştur Ortalama sıcaklık, maksimum ve minimum sıcaklık azaldıkça KOAH atak nedeni ile hastane başvuru sayısı artmıştır Mevsimsel değişim KOAH başvuru sayısı üzerine anlamlı etkili görüldü. Ayrıca hafta sonu yapılan KOAH başvuruları hafta içine göre anlamlı yüksek bulundu. Ortalama sıcaklık döneminde, başvuru gününde (0. gün) ve hasta başvurusundan önceki 5 günlük süre boyunca KOAH atak ile başvuru sayısının arttığı belirlenmiş ve istatistiksel olarak anlamlı bulunmuştur (p=0.001 p<0.05; p=0.015, p<0.05 ). Nem ve basınç ile KOAH atak başvurusu arasında istatistiksel olarak anlamlı ilişki gözlenmedi. Sonuç: Çalışmamızda iklimsel faktörlerin KOAH atak sıklığı üzerine etkisinin olduğunu gördük ve bu etkinin sıcaklıkla bağlantılı olduğunu tespit ettik. Sıcaklık azaldıkça KOAH alevlenme ile acil servise başvurunun arttığını bulduk. İklim değişikliklerinin etkisi nedeniyle bu konuda geniş çaplı çalışmalara ihtiyaç olduğu kanaatindeyiz.

References

  • 1. Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease. In. 2019
  • 2. Lopez AD, Shibuya K, Rao C, Mathers CD, Hansell AL, Held LS, et al. Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J. 2006 Feb;27(2):397-412.
  • 3. Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease. In. 2020.
  • 4. Hoffmann C, Hanisch M, Heinsohn JB, Dostal V, Jehn M, Liebers U, et al.Increasedvulnerability of COPD patientgroupsto urban climate in view of globalwarming. Int J ChronObstructPulmonDis. 2018 Oct 23;13:3493-3501. doi: 10.2147/COPD.S174148
  • 5. Smith, J. B.,Schneider, S. H., Oppenheimer, M., G W. Yohe , W Hare , M D. Mastrandreaet al. (2009). Assessing dangerous climate change through an update of the Inter governmental Panel on Climate Change (IPCC) ‘‘reasonsforconcern’’. Proceedings of the National Academy of Sciences, 106 (11) 4133-4137; DOI: 10.1073/pnas.0812355106
  • 6. Frumkin, H.,Hess, J., Luber, G., Malilay J, McGeehin M. (2008). Climate change: The public health response. American Journal of Public Health, 98(3), 435_445, https://doi.org/10.2105/AJPH.2007.119362
  • 7. Mäkinen TM, Juvonen R, Jokelainen J,Harju TH, Peitso A, Bloigu A, Silvennoinen-Kassinen A,Leinonen M, Hassi J.Cold temperature and low humidity are associated with increased occurrence of respiratory tract infections. Respir Med. 2009 Mar;103(3):456-62. doi: 10.1016/j.rmed.2008.09.011. Epub 2008 Nov 1. PMID: 18977127.
  • 8. Rezende GL, Granjeiro RC, Furtado PL, Pinheiro GB, Nakanishi M. Is Epistaxis The Relationship Between Hospital Admission And Dry Climate Int. Arch. Otorhinolaryngol. 2009; 13 (2): 172-7
  • 9. Gautret P, Gray GC, Charrel RN, et al. Emerging viral respiratory tract infections —environmental risk factors and transmission. Lancet Infect Dis 2014; 14: 1113–1122.
  • 10. Pica N, Bouvier NM. Ambient temperature and respiratory virus infection. The Pediatric Infectious Disease Journal. 2014 Mar;33(3):311-313. DOI: 10.1097/inf.0000000000000235
  • 11. Su, Q.,Liu, H., Yuan, X. et al. Retracted artıcle: The Interaction Effects of Temperature and Humidity on Emergency Room Visitsfor Respiratory Diseases in Beijing, China. Cell Biochem Biophys 70, 1377–1384 (2014). https://doi.org/10.1007/s12013-014-0067-5
  • 12. Silva DR, Viana VP, Mu¨ller AM, et al. Respiratory viral infections and effects of meteorological parameters and air pollution in adults with respiratory symptoms admitted to the emergency room. Influenza Other Respir Viruses 2014; 8: 42–52.
  • 13. duPrel JB, Puppe W, Gro¨ndahl B, et al. Are meteorological parameters associated with acute respiratory tract infections Clin Infect Dis 2009; 49: 861–8.
  • 14. de’Donato F andMichelozzi P. Climatechange, extreme weather events and health effects. In: Giffredo S andDublink Z (eds) The Mediterranean Sea. The Netherlands: Springer, 2014, pp:617–24
  • 15. Tromp SW. Biometeorology-theimpact of the weather and climate on humans and their environment (animals and plants). In: Thomas LC (ed.) Heyden International Topics in Science. London: Heyden& Son Ltd, 1980, pp:263–318.
  • 16. Tromp S and Hoffman JG. Medical biometeorology. PhysicsToday 1964; 17: 53–4.
  • 17. F. De Donatoand P. Michelozzi, “Climate change, extreme weather events and health efects,” e Mediterranean Sea: Its History and Present Challenges, vol. 9789400767041, pp. 617– 624, 2014.]
  • 18. Y. Liu, J. Liu, F. Chen et al., “Impact of meteorological factors on lower respiratory tract infections in children,” Journal of International MedicalResearch, 2015
  • 19. Li M, Li Q, Yang G, Kolosov VP, Perelman JM, Zhou XD. Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitrothrough a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J Allergy ClinImmunol. 2011;128:3. doi:10.1016/j.jaci.2011.04.032
  • 20. Donaldson GC, Seemungal T, Jeffries DJ, Wedzicha JA. Effect of temperature on lung function and symptoms in chronic obstructive pulmonary disease. Eur Respir J. 1999;13:844. doi:10.1034/j.1399-3003.1999.13d25.x
  • 21. H. Lin, Y. Zhang,Xu Y, Xu X, Liu T, Luo Y, Xiao J, Wu W, Ma W. “Temperature Changes between Neighboring Daysand Mortality in Summer: A Distributed Lag Non-Linear Time Series Analysis,” PLoS ONE, vol. 8, no. 6, Article ID e66403, 2013.
  • 22. Is Standard deviation of daily PM2.5 concentration associated with respiratory mortality” Environmental Pollution, vol. 216, pp. 208–214, 2016. [18] A. Zanobetti, M. S. O’Neill, C. J. Gronlund, and J. D. Schwartz,,
  • 23. Summer temperature variability and long-term survival among elderly people with chronic disease,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 109, no. 17, pp. 6608–6613, 2012.
  • 24. Ferrari U, Exner T, Wanka ER, Bergemann C, Meyer-Arnek J, et al. (2012) Influence of airpressure, humidity, solar radiation, temperature, andwindspeed on ambulatory visits due to chronic obstructive pulmonary disease in Bavaria, Germany. Int J Biometeorol 56: 137–43
  • 25. Kurai D, Saraya T, Ishii H, Takizawa H. Astım ve KOAH'ta virüs kaynaklı alevlenmeler. Ön Mikrobiyol. 2013; 4: 293
  • 26. .Tseng CM, Chen YT, Ou SM, et al. Theeffect of coldtemperature on increase dexacerbation of chronic obstructive pulmonary disease: a nationwidestudy. PLoSOne. 2013;8(3):e57066. doi:10.1371/journal.pone.0057066
  • 27. Almagro P, Hernandez C, Martinez-Cambor P, Tresserras R, EscarrabillJ.Seasonality, ambient temperatures and hospitalizations for acute exacerbation of COPD: a population-basedstudy in a metropolitanarea. Int J Chron Obstruct Pulmon Dis. 2015 May 8;10:899-908. doi: 10.2147/COPD.S75710
  • 28. Zhang Y, Liu X, Kong D, Fu J, Liu Y, Zhao Y, Lian H, Zhao X, Yang J, Fan Z.Int J Chron Obstruct Pulmon Dis. 2020 Jan 29;15:213-223. doi: 10.2147/COPD.S224198. eCollection 2020.PMID: 32099346
  • 29. Lee J, Jung HM, Kim SK, et al. Factors associated with chronic obstructive pulmonary disease exacerbation, based on big data analysis. SciRep. 2019;9(1):1–8. doi:10.1038/s41598-019-43167-w 30. Donaldson GC, Goldring JJ, Wedzicha JA. Influence of season on exacerbation characteristics in patientswith COPD. Chest. 2012;141(1):94–100. doi:10.1378/chest.11-0281
  • 31. Y. Liu, J. Liu, F. Chen et al., “Impact of meteorological factors on lower respiratory tract infections in children,” Journal of International Medical Research, vol. 44, no. 1, pp. 30–41, 2016.
  • 32. Lam HC, Chan EY, Goggins WB 3rd.Int J Biometeorol. 2018 Aug;62(8):1447-1460. doi: 10.1007/s00484-018-1542-2. Epub 2018 May 5.PMID: 29730816
  • 33. Mann M, Patel K, Reardon JZ, Goldstein M, Godar TJ, ZuWallack RL. (1993) The influence of spring and summer New England meteorologic conditions on the respiratorystatus of patients with chronic lung disease. Chest 103: 1369–74
  • 34. Loh TP, Lai FYL, Tan ES, Thoon KC, Tee NWS, Cutter J, Tang JW. “Correlations between clinical illness, respiratory virus infections and climate factors in a tropical paediatric population,” Epidemiology and Infection, vol. 139, no. 12, pp. 1884–1894, 2011
  • 35. L. Yang, P. Y. Chen, J. F. He et al., “Efect modifcation of environmental factors on infuenza-associatedmortality: a time-seriesstudy in two Chinesecities,” BMC Infectious Diseases, vol. 11, articleno. 342, 2011
  • 36. Rea H, McAuley S, Jayaram L, Garrett J, Hockey H, et al. (2010) The clinicalutility of long-term humidification therapy in chronic airway disease. RespirMed 104: 525–33.

KOAH akut alevlenmesi ile acil servise başvuran hasta sayısının meteorolojik parametreler arasındaki ilişki

Year 2021, Volume: 54 Issue: 1, 112 - 116, 27.04.2021
https://doi.org/10.20492/aeahtd.884831

Abstract

Amaç: Biz çalışmamızda acil servise bir solunum yolu hastalığı olan KOAH akut alevlenme ile gelen hastaların meterolojik parametrelerden sıcaklık, nem ve hava basınçı etkisiyle hastaneye başvuru sayıları arasındaki ilişkiyi ortaya koymayı amaçladık.
Metod: Bu çalışma rektospektif bir çalışmadır.Acil servise KOAH akut alevlenme ile başvuran hastaların atak sıklığını değerlendirmede sıcaklık, hava basıncı ve nem faktörününün etkisini tespit etmek için yapıldı. Hasta grubu Sincan Dr. Nafiz Körez Devlet Hastanesi Acil Servisine 01.01.2017-31.12.2019 tarihleri arasında başvuran hastalardan oluşturuldu. Bu tarihler arasındaki basınç, sıcaklık ve nem oranı değerleri aynı bölgenin meteorolojik verileri kullanılarak belirlendi.
Bulgular: Toplamda 1095 gün içinde 1082 gün KOAH atak ile başvuru olmuştur. Günde ortalama 6 KOAH’lı hasta başvurmuştur Ortalama sıcaklık, maksimum ve minimum sıcaklık azaldıkça KOAH atak nedeni ile hastane başvuru sayısı artmıştır Mevsimsel değişim KOAH başvuru sayısı üzerine anlamlı etkili görüldü. Ayrıca hafta sonu yapılan KOAH başvuruları hafta içine göre anlamlı yüksek bulundu. Ortalama sıcaklık döneminde, başvuru gününde (0. gün) ve hasta başvurusundan önceki 5 günlük süre boyunca KOAH atak ile başvuru sayısının arttığı belirlenmiş ve istatistiksel olarak anlamlı bulunmuştur (p=0.001 p<0.05; p=0.015, p<0.05 ). Nem ve basınç ile KOAH atak başvurusu arasında istatistiksel olarak anlamlı ilişki gözlenmedi.
Sonuç: Çalışmamızda iklimsel faktörlerin KOAH atak sıklığı üzerine etkisinin olduğunu gördük ve bu etkinin sıcaklıkla bağlantılı olduğunu tespit ettik. Sıcaklık azaldıkça KOAH alevlenme ile acil servise başvurunun arttığını bulduk. İklim değişikliklerinin etkisi nedeniyle bu konuda geniş çaplı çalışmalara ihtiyaç olduğu kanaatindeyiz.

References

  • 1. Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease. In. 2019
  • 2. Lopez AD, Shibuya K, Rao C, Mathers CD, Hansell AL, Held LS, et al. Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J. 2006 Feb;27(2):397-412.
  • 3. Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease. In. 2020.
  • 4. Hoffmann C, Hanisch M, Heinsohn JB, Dostal V, Jehn M, Liebers U, et al.Increasedvulnerability of COPD patientgroupsto urban climate in view of globalwarming. Int J ChronObstructPulmonDis. 2018 Oct 23;13:3493-3501. doi: 10.2147/COPD.S174148
  • 5. Smith, J. B.,Schneider, S. H., Oppenheimer, M., G W. Yohe , W Hare , M D. Mastrandreaet al. (2009). Assessing dangerous climate change through an update of the Inter governmental Panel on Climate Change (IPCC) ‘‘reasonsforconcern’’. Proceedings of the National Academy of Sciences, 106 (11) 4133-4137; DOI: 10.1073/pnas.0812355106
  • 6. Frumkin, H.,Hess, J., Luber, G., Malilay J, McGeehin M. (2008). Climate change: The public health response. American Journal of Public Health, 98(3), 435_445, https://doi.org/10.2105/AJPH.2007.119362
  • 7. Mäkinen TM, Juvonen R, Jokelainen J,Harju TH, Peitso A, Bloigu A, Silvennoinen-Kassinen A,Leinonen M, Hassi J.Cold temperature and low humidity are associated with increased occurrence of respiratory tract infections. Respir Med. 2009 Mar;103(3):456-62. doi: 10.1016/j.rmed.2008.09.011. Epub 2008 Nov 1. PMID: 18977127.
  • 8. Rezende GL, Granjeiro RC, Furtado PL, Pinheiro GB, Nakanishi M. Is Epistaxis The Relationship Between Hospital Admission And Dry Climate Int. Arch. Otorhinolaryngol. 2009; 13 (2): 172-7
  • 9. Gautret P, Gray GC, Charrel RN, et al. Emerging viral respiratory tract infections —environmental risk factors and transmission. Lancet Infect Dis 2014; 14: 1113–1122.
  • 10. Pica N, Bouvier NM. Ambient temperature and respiratory virus infection. The Pediatric Infectious Disease Journal. 2014 Mar;33(3):311-313. DOI: 10.1097/inf.0000000000000235
  • 11. Su, Q.,Liu, H., Yuan, X. et al. Retracted artıcle: The Interaction Effects of Temperature and Humidity on Emergency Room Visitsfor Respiratory Diseases in Beijing, China. Cell Biochem Biophys 70, 1377–1384 (2014). https://doi.org/10.1007/s12013-014-0067-5
  • 12. Silva DR, Viana VP, Mu¨ller AM, et al. Respiratory viral infections and effects of meteorological parameters and air pollution in adults with respiratory symptoms admitted to the emergency room. Influenza Other Respir Viruses 2014; 8: 42–52.
  • 13. duPrel JB, Puppe W, Gro¨ndahl B, et al. Are meteorological parameters associated with acute respiratory tract infections Clin Infect Dis 2009; 49: 861–8.
  • 14. de’Donato F andMichelozzi P. Climatechange, extreme weather events and health effects. In: Giffredo S andDublink Z (eds) The Mediterranean Sea. The Netherlands: Springer, 2014, pp:617–24
  • 15. Tromp SW. Biometeorology-theimpact of the weather and climate on humans and their environment (animals and plants). In: Thomas LC (ed.) Heyden International Topics in Science. London: Heyden& Son Ltd, 1980, pp:263–318.
  • 16. Tromp S and Hoffman JG. Medical biometeorology. PhysicsToday 1964; 17: 53–4.
  • 17. F. De Donatoand P. Michelozzi, “Climate change, extreme weather events and health efects,” e Mediterranean Sea: Its History and Present Challenges, vol. 9789400767041, pp. 617– 624, 2014.]
  • 18. Y. Liu, J. Liu, F. Chen et al., “Impact of meteorological factors on lower respiratory tract infections in children,” Journal of International MedicalResearch, 2015
  • 19. Li M, Li Q, Yang G, Kolosov VP, Perelman JM, Zhou XD. Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitrothrough a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J Allergy ClinImmunol. 2011;128:3. doi:10.1016/j.jaci.2011.04.032
  • 20. Donaldson GC, Seemungal T, Jeffries DJ, Wedzicha JA. Effect of temperature on lung function and symptoms in chronic obstructive pulmonary disease. Eur Respir J. 1999;13:844. doi:10.1034/j.1399-3003.1999.13d25.x
  • 21. H. Lin, Y. Zhang,Xu Y, Xu X, Liu T, Luo Y, Xiao J, Wu W, Ma W. “Temperature Changes between Neighboring Daysand Mortality in Summer: A Distributed Lag Non-Linear Time Series Analysis,” PLoS ONE, vol. 8, no. 6, Article ID e66403, 2013.
  • 22. Is Standard deviation of daily PM2.5 concentration associated with respiratory mortality” Environmental Pollution, vol. 216, pp. 208–214, 2016. [18] A. Zanobetti, M. S. O’Neill, C. J. Gronlund, and J. D. Schwartz,,
  • 23. Summer temperature variability and long-term survival among elderly people with chronic disease,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 109, no. 17, pp. 6608–6613, 2012.
  • 24. Ferrari U, Exner T, Wanka ER, Bergemann C, Meyer-Arnek J, et al. (2012) Influence of airpressure, humidity, solar radiation, temperature, andwindspeed on ambulatory visits due to chronic obstructive pulmonary disease in Bavaria, Germany. Int J Biometeorol 56: 137–43
  • 25. Kurai D, Saraya T, Ishii H, Takizawa H. Astım ve KOAH'ta virüs kaynaklı alevlenmeler. Ön Mikrobiyol. 2013; 4: 293
  • 26. .Tseng CM, Chen YT, Ou SM, et al. Theeffect of coldtemperature on increase dexacerbation of chronic obstructive pulmonary disease: a nationwidestudy. PLoSOne. 2013;8(3):e57066. doi:10.1371/journal.pone.0057066
  • 27. Almagro P, Hernandez C, Martinez-Cambor P, Tresserras R, EscarrabillJ.Seasonality, ambient temperatures and hospitalizations for acute exacerbation of COPD: a population-basedstudy in a metropolitanarea. Int J Chron Obstruct Pulmon Dis. 2015 May 8;10:899-908. doi: 10.2147/COPD.S75710
  • 28. Zhang Y, Liu X, Kong D, Fu J, Liu Y, Zhao Y, Lian H, Zhao X, Yang J, Fan Z.Int J Chron Obstruct Pulmon Dis. 2020 Jan 29;15:213-223. doi: 10.2147/COPD.S224198. eCollection 2020.PMID: 32099346
  • 29. Lee J, Jung HM, Kim SK, et al. Factors associated with chronic obstructive pulmonary disease exacerbation, based on big data analysis. SciRep. 2019;9(1):1–8. doi:10.1038/s41598-019-43167-w 30. Donaldson GC, Goldring JJ, Wedzicha JA. Influence of season on exacerbation characteristics in patientswith COPD. Chest. 2012;141(1):94–100. doi:10.1378/chest.11-0281
  • 31. Y. Liu, J. Liu, F. Chen et al., “Impact of meteorological factors on lower respiratory tract infections in children,” Journal of International Medical Research, vol. 44, no. 1, pp. 30–41, 2016.
  • 32. Lam HC, Chan EY, Goggins WB 3rd.Int J Biometeorol. 2018 Aug;62(8):1447-1460. doi: 10.1007/s00484-018-1542-2. Epub 2018 May 5.PMID: 29730816
  • 33. Mann M, Patel K, Reardon JZ, Goldstein M, Godar TJ, ZuWallack RL. (1993) The influence of spring and summer New England meteorologic conditions on the respiratorystatus of patients with chronic lung disease. Chest 103: 1369–74
  • 34. Loh TP, Lai FYL, Tan ES, Thoon KC, Tee NWS, Cutter J, Tang JW. “Correlations between clinical illness, respiratory virus infections and climate factors in a tropical paediatric population,” Epidemiology and Infection, vol. 139, no. 12, pp. 1884–1894, 2011
  • 35. L. Yang, P. Y. Chen, J. F. He et al., “Efect modifcation of environmental factors on infuenza-associatedmortality: a time-seriesstudy in two Chinesecities,” BMC Infectious Diseases, vol. 11, articleno. 342, 2011
  • 36. Rea H, McAuley S, Jayaram L, Garrett J, Hockey H, et al. (2010) The clinicalutility of long-term humidification therapy in chronic airway disease. RespirMed 104: 525–33.
There are 35 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Original research article
Authors

Eren Usul 0000-0003-3980-6768

Avni Uygar Seyhan 0000-0002-2337-5484

Publication Date April 27, 2021
Submission Date February 22, 2021
Published in Issue Year 2021 Volume: 54 Issue: 1

Cite

AMA Usul E, Seyhan AU. KOAH akut alevlenmesi ile acil servise başvuran hasta sayısının meteorolojik parametreler arasındaki ilişki. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. April 2021;54(1):112-116. doi:10.20492/aeahtd.884831