Amaç: Bu çalışmada, gebe kadınlarda konjenital infeksiyon etkenlerinden TORCH Grubunun seropozitifliğinin araştırılması amaçlandı.
Gereç ve Yöntem: Çalışmaya 2020-11/2022 yılları arasında başvuran 20-46 yaşları arasındaki 1000 gebe dahil edildi. Retrospektif olarak incelendi. Testler ELISA yöntemiyle çalışıldı.
Bulgular:
Çalışmaya katılan 1000 gebe yaş ortalaması 28,07± 5,9 olup en küçüğü 20, en büyüğü ise 46 yaşındaydı. Gebelerin ortalama gebelik haftası 13,35±9,2 hf idi. Toplam 1000 gebenin 1000‘inde (%100) Anti HIV antikoru negatifti. 1000 gebenin 991 ‘inde (%99,1) HBsAg negatif, 9’unda (%0,9) pozitifti. 27 gebenin (%100) Anti CMV IgG değeri pozitifti. 43 gebenin 7 ‘sinde (%16,3) Anti Rubella IgG negatif, 36’sında (%83,7) pozitifti. 314 gebenin 312 ‘inde (% 99,36) Anti Toxoplazma IgM negatif, 2’sinde (%0,6) pozitifti.
Sonuç: Gebelerde Rubella- IgG, CMV-IgG seropozitiflik oranları ile HBsAg pozitifliği oranları Türkiye verileri ile benzer olduğu saptandı. AntiHBs antikor oranının yüksek, Anti Toxoplazma IgG pozitiflik oranının (%17,1) ise Türkiye ortalamasından daha düşük olduğu saptandı.
Gebelerin aşıyla önlenebilen Hepatit B , Rubella infeksiyon etkenleri için, seronegatif gebelerin uygun zamanda aşılanması gerekir. Ayrıca, T.gondii bulaş yolları gebelere anlatılarak, gelişebilecek yenidoğan mortalite ve morbidite oranlarını azaltacağı görüşündeyiz.
Anahtar kelimeler: Gebelik, T.gondii, CMV, Rubella, Hepatit B, HIV, seroprevalans
T.gondii Hepatitis B Pregnancy CMV Rubella HIV seroprevalence
Objective: In this study, it was aimed to investigate the seropositivity of the TORCH Group, which is one of the congenital infectious agents in pregnant women.
Materials and Methods: 1000 pregnant women between the ages of 20-46 who applied between 2020-11/2022 were included in the study. It was reviewed retrospectively. The tests were performed with the ELISA method.
Results:
The mean age of 1000 pregnant women who participated in the study was 28.07± 5.9 years, the youngest was 20 and the oldest was 46 years old. The mean gestational week of the pregnant women was 13.35±9.2 weeks. Anti HIV antibody was negative in 1000 (100%) of a total of 1000 pregnant women. HBsAg was negative in 991 (99.1%) of 1000 pregnant women and positive in 9 (0.9%). Anti CMV IgG values of 27 pregnant women (100%) were positive. Anti Rubella IgG was negative in 7 (16.3%) of 43 pregnant women and positive in 36 (83.7%). Anti Toxoplasma IgM was negative in 312 (99.36%) of 314 pregnant women and positive in 2 (0.6%).
Conclusion: Rubella-IgG, CMV-IgG seropositivity rates and HBsAg positivity rates in pregnant women were found to be similar to Turkish data. It was determined that the AntiHBs antibody rate was high and the Anti Toxoplasma IgG positivity rate (17.1%) was lower than the Turkey average.
Seronegative pregnant women should be vaccinated at the appropriate time for hepatitis B and Rubella infectious agents, which can be prevented by vaccination. In addition, we believe that explaining the transmission routes of T.gondii to pregnant women will reduce the rates of neonatal mortality and morbidity that may develop.
Key words: Pregnancy, T.gondii, CMV, Rubella, Hepatitis B, HIV, seroprevalence
T.gondii Hepatitis B Pregnancy CMV Rubella HIV seroprevalence
Primary Language | Turkish |
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Subjects | Clinical Sciences |
Journal Section | Original research article |
Authors | |
Publication Date | December 31, 2022 |
Submission Date | November 25, 2022 |
Published in Issue | Year 2022 Volume: 55 Issue: 3 |