Çocukluk çağında Guillain Barre Sendromu: Bir olgu serisi

Year 2023, Volume: 56 Issue: 1, 48 - 51, 30.04.2023

Arzu Yılmaz , Rabia Meral Olcay Tosun Meriç

https://doi.org/10.20492/aeahtd.1061873

Abstract

Amaç: Guillain Barre Sendromu (GBS) hızla ilerleyen, asendan, simetrik zayıflık ve arefleksi ile karakterize akut inflamatuar bir polinöropatidir. Çocukluk çağında akut flask paralizinin en sık nedenidir. Sıklıkla ilerleyici güçsüzlük, ilişkili hafif duyusal semptomlar ve spesifik olmayan enfeksiyondan birkaç gün veya hafta sonra ortaya çıkan albüminositolojik ayrışma ile karakterizedir. Nörolojik defisit günler ve aylar içinde ilerler.
Gereç ve Yöntem: Bu çalışmada 2016-2018 yılları arasında kliniğimize başvuran farklı klinik bulgulara sahip toplam 7 GBS olgusu sunuldu.
Bulgular: İki hastada akut motor aksonal nöropati (AMAN), iki hastada akut inflamatuar demiyelinizan polinöropati (AIDP), bir hastada Miller Fischer sendromu (MFS), bir hastada Bickerstaff beyin sapı ensefaliti (BBE) ve bir hastada atipik tanı konuldu. Guillain Barre sendromu. AMAN'lı olgularda solunum desteği gerekti ve bunlardan birinde ventilatör ilişkili pnömoni ve tansiyon pnömotoraks gelişti.
Sonuç: Tüm olgular sekelsiz iyileşti.

Keywords

Guillain-Barré Sendromu, çocukluk, AMAN, AIDP, MFS, BBE, Guillain-Barré Sendromu, çocukluk, AMAN, AIDP, MFS, BBE

Guillain Barre Syndrome in childhood: A case series

Abstract

Aim: Guillain Barre Syndrome (GBS) is an acute inflammatory polyneuropathy characterized by rapidly progressive, ascending, symmetric weakness and areflexia. It is the most common cause of acute flask paralysis in childhood. It is frequently characterized by progressive weakness, associated mild sensory symptoms, and albuminocytologic dissociation that often occur several days or weeks after nonspecific infection. The neurological deficit progresses in days and months.
Material and Method: In this study, a total of 7 GBS cases with different clinical manifestations admitted to our clinic between 2016 and 2018 were presented.
Results: Two patients were diagnosed with acute motor axonal neuropathy (AMAN), two patient with acute inflammatory demyelinating polyneuropathy (AIDP), one patient with Miller Fischer syndrome (MFS), one patient with Bickerstaff's brainstem encephalitis (BBE)and one patient with atypical Guillain Barre syndrome. The cases with AMAN necessitated respiratory support and ventilator-associated pneumonia and tension pneumothorax developed in one of them.
Conclusion: All cases healed without any sequels.

Keywords

Guillain-Barré Syndrome, childhood, AMAN, AIDP, MFS, BBE, Guillain-Barré Syndrome, childhood, AMAN, AIDP, MFS, BBE

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