Obeziteyle İlişkili Güncel Peptitlere Yeni Yaklaşımlar

Year 2024, , 111 - 120, 29.04.2024

Sümeyye Koç , Levent Sarıyıldız , Esma Menevşe

https://doi.org/10.46332/aemj.1215675

Abstract

Özellikle çocukluk ve adölesan zamanlarında gelişen obezite, her yaşta önemli bir sağlık sorunu olarak karşımıza çıkmaktadır. Hipotalamusu vücudun enerji depoları hakkında uyaran hormonlar, yemek yemeyi engelleyip vücut ağırlığının belli fizyolojik sınırlar içerisinde kalmasını sağlamaktadırlar. Obezite ve obeziteyle ilişkili olan hormonların araştırılması bu kapsamda çok önemlidir. Obezite ile ilişkili hormonların günümüze kadar tespit edilmiş olan fonksiyonlarının, daha ileri çalışmalara rehberlik edebileceğini düşünmekteyiz. Bu derlemede obeziteyle ilişkili hormonlar ve onların etki mekanizmalarına değinilmiştir.

Keywords

ghrelin, irisin, leptin, nesfatin-1, nöropeptid-y, oreksin

New Perspectives on Obesity Related Novel Peptides

Abstract

Obesity, which develops especially in childhood and adolescence, is an important health problem at all ages. Hormones that stimulate the hypothalamus about the body's energy stores prevent eating and keep body weight within certain physiological limits. Investigating obesity and the hormones associated with obesity is very important in this context. We believe that the functions of obesity-associated hormones that have been identified to date can guide further studies. In this review, obesity-related hormones and their mechanisms of action are discussed.

Keywords

ghrelin, irisin, leptin, nesfatin-1, neuropeptide-y, orexin

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