Pertrokanterik Kalça Kırığı Geçiren Yaşlı Hastalarda Yüksek Nötrofil-Lenfosit Oranı ile Postoperatif 1 Yıllık Mortalite Arasındaki İlişki

Year 2024, Volume: 8 Issue: 2, 223 - 228, 27.08.2024

Hicabi Sezgin , Furkan Erdoğan , Özkan Öztürk , Emre Çalışal

https://doi.org/10.46332/aemj.1437951

Abstract

Amaç: Araştırma, yaşlı hastalarda kalça kırığı ameliyatı geçiren bireylerde perioperatif nötrofil/lenfosit oranının (NLR) mortalite üzerindeki prognostik değerini incelemeyi amaçlamaktadır.

Araçlar ve Yöntem: Çalışmaya dahil edilen 236 hasta (%68.6 kadın ve %31.4 erkek), belirlenen kriterlere uyan ve kalça kırığı ameliyatı geçiren bireylerden oluşmaktadır. Hastaların kabul anındaki tam kan sayımı ve beşinci postoperatif günkü değerleri kaydedilmiştir. Kabul anındaki (NLR-D0) ve beşinci postoperatif günkü (NLR-D5) NLR değerleri ana değişken olarak belirlenmiştir.

Bulgular: Hastaların yaş ortalaması 80.1±7.9 yıldır (65-99). Hayatta kalan hastaların ortalama NLR-D0 ve NLR-D5 değerleri sırasıyla 6.54 ve 4.55'tir. Vefat eden hastaların ise ortalama NLR-D0 ve NLR-D5 değerleri sırasıyla 6.99 ve 8.90'dır. Hayatta kalanlar ve vefat edenler arasında NLR açısından anlamlı bir fark bulunmuştur. NLR-D0 değerlerinin yaşayanlar ve ölenler arasında anlamlı bir fark oluşturmadığı, ancak NLR-D5 değerinin ölenlerde belirgin şekilde yüksek olduğu görülmüştür. Birinci postoperatif yıl sonundaki mortalite oranı %35.2'dir.

Sonuç: Kalça kırığı ameliyatı geçiren yaşlı hastalarda beşinci postoperatif gündeki yüksek NLR değeri (NLR-D5>7.85), 1 yıllık mortaliteyi öngörmede bir belirleyici olabilir.

Keywords

biyobelirteçler , geriatri , kırılganlık , sağkalım , travma

Association between Increased Neutrophil-To-Lymphocyte Ratio and Postoperative 1-Year Mortality in Elderly Patients with Pertrochanteric Hip Fracture

Abstract

Purpose: This study aimed to examine the prognostic value of perioperative NLR level in terms of mortality in the first postoperative year in elderly patients undergoing hip fracture surgery.

Materials and Methods: The study included 236 patients (68.6% female and 31.4% male) who met the specified criteria and had undergone hip fracture surgery. Complete blood counts were recorded at admission and on the fifth postoperative day. Neutrophil-to-lymphocyte ratios (NLR) at admission (NLR-D0) and on the fifth postoperative day (NLR-D5) were identified as the primary variables.

Results: The mean age of the participants was 80.1±7.9 years (min: 65 years to max: 99 years). The mean NLR-D0 and mean NLR-D5 values of surviving patients were 6.54 and 4.55, respectively. The mean NLR-D0 and mean NLR-D5 values of patients who died were 6.99 and 8.90, respectively. A significant difference was found in the NLR variability of the patients who survived and those who died. The examination of the effects of NLR-D0 and NLR-D5 parameters on mortality revealed no significant difference in NLR-D0 values between the patients who lived and those who died (p>0.05), but the NLR-D5 value was significantly higher in the patients who died. The mortality rate at the end of the first postoperative year was 35.2%.

Conclusion: A high NLR value (NLR-D5>7.85) on the fifth postoperative day in elderly patients undergoing hip fracture surgery may be a predictor of 1-year mortality after hip fracture surgery.

Keywords

biomarkers , frailty , geriatric , survival , trauma

Ethical Statement

The author declares that there is no conflict of interest. This study was found ethically appropriate by the Ahi Evran University Clinical Research Ethics Committee on 09.04.2020 with the decision number KAEÜKAEK 2020-06/44. No budget was used for the study.

Supporting Institution

None

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