Diffusion-Weighted Imaging of Solid Ovarian Masses: Is it Useful to Differentiate Benign From Malignant?

Year 2021, , 191 - 196, 22.12.2021

Mehmet Ali Gültekin

https://doi.org/10.46332/aemj.793994

Abstract

Purpose: To research whether apparent diffusion coefficient (ADC) values of solid ovarian masses are beneficial for differentiation between benign and malignant.

Materials and Methods: We analyzed 50 patients with 62 solid ovarian masses retrospectively. We divided the ovarian masses into two groups as benign and malignant. Thirteen patients with 13 solid ovarian masses were identified to have benign masses, while 37 patients with 49 solid ovarian masses were diagnosed with malignancy. The Mann-Whitney U test was used for the comparisons of the sizes and the ADC values of solid ovarian mass. Receiver-operating characteristic (ROC) curves were analyzed to determine a cutoff value for ADC to differentiate benign from malignant.

Results: No significant differences were found between the two groups in terms of age (p=0.06), whole lesion size (p= 0.647), and solid component size (p=0.066). ADC values of the two groups were significantly different (p=0.015). Malignant solid ovarian lesions showed significantly lower ADC values than benign lesions. The ROC curves showed an area under the curve rate of 0.722 and a cutoff value of 886 x 10-6 mm2/s.

Conclusion: Diffusion-weighted imaging is a useful method for differential diagnosis of solid ovarian masses. Lower ADC values of solid ovarian lesions indicate malignancy rather than benign lesions.

Keywords

Solid ovarian mass, Apparent diffusion coefficient, Diffusion weighted imaging

Solid Over Kitlelerinde Difüzyon Ağırlıklı Görüntüleme: Benign-Malign Ayrımında Faydalı Mı?

Abstract

Amaç: Apparent diffusion coefficient (ADC) değerlerinin benign-malign solid over kitlelerinin ayrımında faydalı olup olmadığını araştırmak.

Araçlar ve Yöntem: Çalışmamıza geriye dönük olarak 50 hastanın 62 solid over kitlesi dahil edildi. Hastalar benign ve malign olmak üzere 2 gruba ayrıldı. On üç hastanın 13 over kitlesi benign tanı alırken, 37 hastanın 49 over kitlesi malign tanı aldı. Lezyon boyutları ve solid over kitlelerinin ADC değerlerinin karşılaştırılmasında Mann-Whitney U testi kullanıldı. Malign-benign ayrımında bir cut-off
ADC değeri hesaplamak için receiver-operating characteristic (ROC) eğrisi kullanıldı.

Bulgular: Gruplar arasında yaş (p=0.06), tüm lezyon boyutu (p= 0.647) ve solid komponent boyutu (p=0.066) arasında istatistiksel anlamlı farklılık yoktu. İki grup arasında ADC değerlerinde anlamlı farklılık saptandı (p=0.015). ADC değerleri istatistiksel anlamlı olarak malign grupta daha düşüktü. ROC analizi ile eğri altında kalan alan 0.722 ve cut-off ADC değeri 0.886 x 10-3 mm2/s olarak
hesaplandı.

Sonuç: Difüzyon ağırlıklı görüntüleme solid over kitlelerinin ayırıcı tanısında kullanışlı bir tekniktir. Solid over kitlelerinde düşük ADC değerleri benign lezyondan ziyade malign bir lezyona işaret etmektedir.

Keywords

Solid over kitlesi, Apparent diffusion coefficient, Difüzyon ağırlıklı görüntüleme

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