Evaluation of Risk Factors ın Children with Febrile Convulsions

Abstract

Purpose: Febrile Convulsions are the most common type of seizures in childhood. This study was conducted to investigate the clinical characteristics of patients being monitored for Febrile Convulsions and to determine their risk factors.

Materials and Methods: A total of 166 patients who were being treated in Kırşehir Training and Research Hospital Pediatrics service with the febrile convulsions diagnosis were included in the study. The data used in the study were obtained retrospectively from medical records. The patients were examined in terms of their age, gender, family history, simultaneous biochemistry values, and
complete blood count parameters. This study was approved by the Kırşehir Ahi Evran University Faculty of Medicine Clinical Research Ethics Committee.

Results: Simple Febrile Convulsions were present in 131 of the patients (79%) and Complicated Febrile Convulsions were present in 35 of them (21%). Upper respiratory tract infection was defined as the most common (78%) in the etiology. Febrile Convulsions recurred in 27 (16%) of the patients. There was a family history of Febrile Convulsions in 37 (22.2%) of the patients, and a family
history of epilepsy in 14 (8.4%). The serum sodium, potassium, chlorine, calcium, and platelet levels of patients with febrile convulsions were significantly lower than the control group, and the glucose, creatine kinase, C-reactive protein levels were significantly higher (P<001).

Conclusion: In early childhood, upper respiratory tract infections and serum electrolyte disturbances were found to be the most important risk factors for Febrile Convulsions for patients with a genetic predisposition.

Keywords

• electrolyte disorders
• febrile convulsions
• risk factors

Febril Konvülziyonlu Çocuklarda Risk Faktörlerinin Değerlendirilmesi

Abstract

Amaç: Febril Konvülziyon çocukluk yaş grubunda en sık görülen nöbet şeklidir. Bu çalışma febril konvülziyon tanısıyla izlenen hastaların klinik özelliklerini araştırmak ve risk faktörlerini belirlemek amacıyla yapılmıştır.

Araçlar ve Yöntem: Febril konvülziyon tanısıyla Kırşehir Eğitim ve Araştırma Hastanesi Pediatri Servisinde takip edilen, 166 hasta çalışmaya alındı. Çalışmadaki veriler retrospektif olarak tıbbi kayıtlardan elde edildi. Hastalar yaş, cinsiyet, aile hikayesi, eş zamanlı biyokimya değerleri ve tam kan parametreleri açısından incelendi. Bu çalışma Kırşehir Ahi Evran Üniversitesi Tıp Fakültesi Klinik
Araştırmalar Etik Kurulu tarafından onaylandı.

Bulgular:131 hastada (%79) Basit Febril Konvülziyon ve 35 hastada (%21) Komplike Febril Konvülziyon mevcuttu. Etiyolojide en sık (%78) üst solunum yolu enfeksiyonu tanımlandı. Hastaların 27’sinde (%16) febril konvülziyon tekrarladı. Hastaların 37 ‘sinde (%22.2) ailede febril konvülziyon hikayesi, 14’ünde (%8.4) ailede epilepsi hikayesi mevcuttu. Febril konvülziyonlu hastalarda serum
sodyum, potasyum, klor, kalsiyum, trombosit düzeyleri kontrol grubuna göre anlamlı olarak düşük, glukoz, kreatin kinaz, C- reaktif protein düzeyi anlamlı yüksek saptandı (p<001).

Sonuç: Erken çocukluk döneminde, genetik yatkın olan hastalarda üst solunum yolu enfeksiyonları ve serum elektrolit bozuklukları febril konvülziyon için en önemli risk faktörleri olarak bulundu.

Keywords

• elektrolit bozuklukları
• febril konvülziyon
• risk faktörleri

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