The Effect of Smoking Addiction on Non-invasive Perfusion Parameters in Asymptomatic Smokers

Year 2021, Volume: 5 Issue: 3, 252 - 257, 22.12.2021

Mustafa Kaçmaz

https://doi.org/10.46332/aemj.880945

Abstract

Purpose: Tobacco use is one of the leading causes of illness and premature death. According to the estimates of the World Health Organization, tobacco is responsible for approximately 9% of deaths worldwide. However, most of the smokers think that they have no abnormal findings due to smoking, especially in the asymptomatic period. In our study, it was aimed to determine whether there
is an early deterioration in some perfusion parameters in asymptomatic cigarette addicts.

Materials and Methods: The study was carried out randomized and prospectively on 140 people with 70 volunteers in each group. Measurements were made with the Masimo rainbow SET device. Basic perfusion parameters were recorded.

Results: Heart rate, methemoglobin (SpMet) and carboxyhemoglobin (SpCO) levels were found to be significantly higher in the smoking group (p<0.05). No significant difference was found between the two groups in perfusion Index (PI) and pleth variability index (PVI) measurements (p≥0.05). No correlation was found between the duration of dependence and basic perfusion parameters
in smokers (p≥0.05).

Conclusion: Smokers may have high spCO and SpMet and heart rate even when they are still in the asymptomatic period, and these findings may be a predictor of future major organ dysfunctions.

Keywords

cigarette, perfusion, methemoglobinemia, carboxyhemoglobin

Asemptomatik İçicilerde Sigara Bağımlılığının Noninvaziv Perfüzyon Parametrelerine Etkisi

Abstract

Amaç: Tütün kullanımı, hastalıkların ve erken ölümlerin önde gelen nedenlerinden biridir. Dünya Sağlık Örgütünün tahminlerine göre tütün, dünya çapındaki ölümlerin yaklaşık %9'undan sorumludur. Ancak çoğu sigara tiryakisi özellikle asemptomatik dönemde iken sigaraya bağlı hiçbir anormal bulgularının olmadığını düşünmektedirler. Çalışmamızda asemptomatik sigara bağımlılarında, bazı perfüzyon parametrelerinde erken dönemde bozulma olup olmadığının tespit edilmesi amaçlanmıştır. 

Araçlar ve Yöntem: Çalışma randomize ve prospektif olarak her grupta 70 gönüllü olmak üzere toplam 140 kişi üzerinde gerçekleştirildi. Ölçümler Masimo rainbow SET cihazı ile gerçekleştirildi. Temel perfüzyon parametreleri kayıt altına alındı.

Bulgular: Kalp atım hızı, methemoglobin (SpMet) ve karboksihemoglobin (SpCO) düzeyinin sigara kullanan grupta anlamlı düzeyde yüksek olduğu görüldü (p<0.05). Perfüzyon indeksi (PI) ve Plet değişkenlik indeksi (PVI) ölçümlerinde ise her iki grup arasında anlamlı düzeyde fark bulunamadı (p≥0.05). Sigara kullananlarda bağımlılık süresi ile temel perfüzyon parametreleri arasında korelasyona rastlanmadı (p≥0.05). 

Sonuç: Sigara kullanan bireyler henüz asemptomatik dönemde bile olsalar, yüksek düzeyde spCO, SpMet ve kalp atım hızına sahip olabilir. Bu bulgular, ilerde oluşabilecek önemli organ disfonksiyonlarının bir ön habercisi olabilir.

Keywords

SİGARA, PERFÜZYON, METHEMOGLOBİN, KARBOKSİHEMOGLOBİN

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