Büyük Akciğer Kistlerinin Romatizmal Bir Nedeni: Sjögren Sendromu

Year 2022, Volume: 6 Issue: 2, 220 - 223, 30.08.2022

Hüseyin Kaplan Senem Şaş Emre Şenköy Gizem Cengiz

https://doi.org/10.46332/aemj.1027156

Abstract

Sjögren sendromu (SjS) glandüler ve ekstraglandüler manifestasyonlara sahip kronik otoimmün bir hastalıktır. Sistemik tutulumlardan etkilenen organlardan bir tanesi de akciğerdir. Pulmoner yapılardaki tutulum hava yolu anormallikleri veya intersitisyel akciğer hastalığı şeklinde görülebilir. Ayrıca, primer SjS’li hastaların bilgisayarlı toraks tomografisinde oldukça değişik paternlerde kistik değişiklikler saptanabilir. Kistik akciğer hastalığı SjS’li hastaların %20 kadarında görülür ve boyutları genellikle 3 cm den daha azdır. Bu yazıda SjS tanılı bir hastanın intersitisyel akciğer hastalığına eşlik eden kistik tutulum örneği güncel literatür eşliğinde sunulmaktadır.

Keywords

akciğer hastalıkları, kist, sjögren sendromu

A Rheumatic Cause of Large Lung Cysts: Sjögren's Syndrome

Abstract

Sjögren's syndrome (SjS) is a chronic autoimmune disease with glandular and extra glandular manifestations. One of the organs affected by systemic involvement is the lung. Involvement of pulmonary structures can be seen as airway abnormalities or interstitial lung disease. In addition, cystic changes in quite different patterns can be detected on thorax computed tomography in patients with

primary SjS. Cystic lung disease occurs in up to 20% of patients with SjS and is usually less than 3 cm in size. In this article, an example of cystic involvement accompanying interstitial lung disease in a patient with SjS is presented in the light of current literature.

Keywords

cyst, lung diseases, sjogren’s syndrome

References

• 1. Thorne I, Sutcliffe N. Sjögren's syndrome. Br J Hosp Med. 2017;78(8):438-442.
• 2. Luppi F, Sebastiani M, Silva M, et al. Interstitial lung disease in Sjögren’s syndrome: a clinical review. Clin Exp Rheumatol. 2020;38(4):291-300.
• 3. Gupta S, Ferrada MA, Hasni SA. Pulmonary manifestations of primary Sjögren's syndrome: Underlying immunological mechanisms, clinical presentation, and management. Front Immunol. 2019;10:1327.
• 4. Chung A, Wilgus ML, Fishbein G, Lynch III JP. Pulmonary and bronchiolar involvement in Sjogren's syndrome. Semin Respir Crit Care Medicine. 2019;40(2):235-254.
• 5. Hatron P-Y, Tillie-Leblond I, Launay D, Hachulla E, Fauchais AL, Wallaert B. Pulmonary manifestations of Sjögren's syndrome. Presse Méd. 2011;40(1):71-86.
• 6. Martínez-Balzano CD, Touray S, Kopec S. Cystic lung disease among patients with Sjögren syndrome: frequency, natural history, and associated risk factors. Chest. 2016;150(3):631-639.
• 7. Shiboski CH, Shiboski SC, Seror R, et al. 2016 ACREULAR classification criteria for primary Sjögren’s syndrome: a consensus and data-driven methodology involving three international patient cohorts. Arthritis Rheumatol. 2017;69(1):35-45.
• 8. Van den Hoogen F, Khanna D, Fransen J, et al. Classification criteria for systemic sclerosis: an ACREULAR collaborative initiative. Arthritis Rheumatism. 2013;65(11):2737-2747.
• 9. Lechtman S, Debray M-P, Crestani B, et al. Cystic lung disease in Sjögren's syndrome: an observational study. Joint Bone Spine. 2017;84(3):317-321.
• 10. Panchabhai TS, Farver C, Highland KB. Lymphocytic interstitial pneumonia. Clin Chest Med. 2016;37(3):463-474.
• 11. Fabre A. Cystic lung disease. Diagn. Histopathol. 2019;25(8):291-303.
• 12. Mariette X, Criswell LA. Primary Sjögren’s syndrome. N Engl J Med. 2018;378(10):931-939.
• 13. Brito-Zeron P, Baldini C, Bootsma H, Bowman SJ, Jonsson R, Mariette X, Sivils K, Theander E, Tzioufas A, Ramos-Casals M. Sjögren syndrome. Nat Rev Dis Primers. 2016;2(1):1-20.
• 14. Fayyaz A, Kurien BT, Scofield RH. Autoantibodies in Sjögren’s syndrome. Rheum Dis Clin North Am. 2016;42(3):419-434.
• 15. Van Ginkel MS, Glaudemans AW, van der Vegt B, et al. Imaging in primary Sjögren’s syndrome. J Clin Med. 2020;9(8):2492.
• 16. Matsuyama N, Ashizawa K, Okimoto T, Kadota J, Amano H, Hayashi K. Pulmonary lesions associated with Sjogren's syndrome: radiographic and CT findings. Br J Radiol. 2003;76(912):880-884.
• 17. Vassiliou V, Moyssakis I, Boki K, Moutsopoulos H. Is the heart affected in primary Sjogren's syndrome? An echocardiographic study. Clin Exp Rheumatol. 2008;26(1):109-112.