Bell Paralizisi Olan Hastalarda Hematolojik Parametrelerin Prognostik Değeri Var Mıdır?

Year 2022, Volume: 6 Issue: 3, 304 - 309, 25.12.2022

Muhammed Gazi Yıldız , İsrafil Orhan , İrfan Kara , Saime Sağıroğlu , Nagihan Bilal , Adem Doğaner , Muhammed Seyithanoğlu

https://doi.org/10.46332/aemj.1008500

Abstract

Amaç: Bu çalışmanın amacı, Bell Paralizisi (BP) olan hastalarda Sistemik İmmun İnflamasyon İndeksi (SII), Nötrofil/Lenfosit Oranı (NLO), Platelet/Lenfosit Oranının (PLO) prognoza katkısını araştırmaktı.

Araçlar ve Yöntem: BP tanısı olan 71 hasta ve kontrol grubu 40 kişi olan katılımcıların verileri retrospektif olarak değerlendirildi. Çalışma kapsamında hastaların yaşları, cinsiyetleri, BP tarafı, House-Brackmann Skorlama (HBS) sistemine göre evreleri, NLO, PLO ve SII oranları ayrıntılı olarak değerlendirildi. BP grubu, Ayrıca BP hastalarda ROC analizi yapılmış, prognostik önemi olabilecek parametreler değerlendirildi.

Bulgular: Yaş ve cinsiyet dağılımı açısından gruplar uyumlu idi. BP hastalarında NLO, PLO, SII değerlerindeki yükseklik istatistiksel açıdan anlamlı idi. ROC analizinde özellikle SII parametresi prognoz açısından daha değerli bulundu.

Sonuç: BP inflamatuar bir bileşeni mevcuttur. SII, NLO, PLO inflamatuar durumu gösterir ve prognostik belirteç olarak kullanılabilir.

Keywords

fasiyal paralizi, inflamasyon, sistemik immun inflamasyon indeksi

Can Hematological Parameters Have a Prognostic Value in Bell’s Palsy Patients?

Abstract

Purpose: The study aim was to investigate the contribution of the Systemic Immune-Inflammation Index (SII), neutrophil-to-lymphocyte ratio (NLR) and that platelet-to-lymphocyte ratio (PLR) to the prognosis of Bell’s palsy patients.

Materials and Methods: Data of 71 patients with Bell’s palsy and 40 participants in control group were retrospectively evaluated. Within the study scope, patients were assessed in detail according to patient age, gender, BP side, House-Brackmann score (HBS) system grading, NLR, PLR, and SII ratios. In addition, ROC analysis was performed in BP patients, and parameters that may have prognostic significance were evaluated.

Results: The groups were matched in terms of age and gender distribution. NLR, PLR, and SII values were statistically significant in BP patients. Especially SII parameter was found to be more valuable for prognosis in the ROC analysis.

Conclusion: Bell’s palsy has an inflammatory component. SII, NLR, LR values can indicate an inflammatory condition in these patients. They may be used as markers and prognostic indicators in Bell’s palsy.

Keywords

facial paralysis, inflammation, systemic immune inflammation index

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