Kan Grupları ile Psoriatik Artrit Arasında Herhangi İlişki Yoktur

Year 2023, Volume: 7 Issue: 2, 183 - 189, 07.08.2023

Samet Karahan , Kemal Özyurt

https://doi.org/10.46332/aemj.1018765

Abstract

Giriş: Psoriatik artrit (PsA) inflamatuar bir kas-iskelet sistemi hastalığıdır. PsA'nın kesin nedenleri belirlenmemiştir. Halen ABO ve Rh kan grupları birçok hastalık için ilgi alanı olmaya devam etmektedir. Bu çalışmada, PsA'da ABO ve Rh kan gruplarının dağılımında farklılık olup olmadığının araştırılması amaçlandı.

Araçlar ve Yöntemler: Ocak 2019-Haziran 2020 tarihleri arasında Orta Anadolu'da üçüncü basamak bir hastanenin erişkin Romatoloji polikliniğine ardışık olarak başvuran 233 PsA hastası kaydedildi. Hastaların kan grupları, 1 Ocak 2019- 31 Haziran 2020 tarihleri arasında aynı hastanede elektif operasyon öncesi tetkik edilen 6280 kişinin kan grupları ile karşılaştırıldı. Kontrol hastalarından tıbbi kayıtlarında 14’ünde Psoriazis / PsA varlığı nedeniyle çalışma dışı bırakıldı. Ayrıca 1 Ocak 2019 ile 1 Temmuz 2020 tarihleri arasında Türk Kızılayı Kayseri Kan Merkezi'ne gönüllü olarak kan bağışı yapan 38.416 kişinin (donör grubu) kan grupları, kontrol grubundakilerin kan grupları ile karşılaştırıldı.

Bulgular: PsA hastaları ile kontrol grubu arasındaki istatistiki kıyaslamada herhangi bir kan grubunda hem kadınlarda hem erkeklerde hem de kümülatif olarak anlamlı bir fark saptanmadı.

Sonuç: Çalışmanın sonucu, PsA'lı hastalar ile kontrol grubu arasında kan grupları arasında anlamlı bir fark olmadığını göstermektedir.

Keywords

ABO Kan Grubu, Psoriasis, Psoriatik Artrit, Rh Kan Grubu

Supporting Institution

yok

Project Number

yok

No Relationship Between Blood Groups and Psoriatic Arthritis

Abstract

Purpose: Psoriatic arthritis (PsA) is an inflammatory musculoskeletal disease. The exact causes of PsA have not been identified. ABO and Rh blood groups continue to be an area of interest for various diseases. In this study, we aimed to evaluate whether there is any difference in the distribution of ABO and Rh blood groups in PsA.

Materials and Methods: 233 PsA patients (PsA group) consecutively referred to the adult rheumatology outpatient clinics of a tertiary care hospital of central Anatolia between January 2019 and June 2020 were enrolled. The blood groups of the PsA group were compared with the blood groups of 6280 individuals who tested before elective operations at the same hospital between 1 January 2019 and 31 June 2020 (Control Group). Fourteen of the control group were excluded due to the presence of psoriasis/PsA in their medical records. In addition, the blood groups of 38.416 people who voluntarily donated blood to the Turkish Red Crescent Kayseri Blood Center between January 1, 2019 and July 1, 2020 (donor group) were compared with the blood groups of the control group.

Results: There was no significant difference between the PsA patients and the control group in any blood group, both in women, men and also cumulatively.

Conclusion: The result of the study shows there is no significant difference in the blood groups between patients with PsA and the control group.

Keywords

ABO Blood Group, Psoriatic Arthritis, Psoriasis, Rh Blood Group

Project Number

yok

References

• 1. Storry JR, Castilho L, Chen Q et al. International society of blood transfusion working party on red cell immunogenetics and terminology: report of the Seoul and London meetings. ISBT Sci Ser. 2016;11(2):118-122.
• 2. Josephson CD, Castillejo M-I, Grima K, Hillyer CD. ABO-mismatched platelet transfusions: strategies to mitigate patient exposure to naturally occurring hemolytic antibodies. Transfus Apher Sci Off J World Apher Assoc Off J Eur Soc Haemapheresis. 2010;42(1):83-88.
• 3. Daniel-Johnson J, Leitman S, Klein H et al. Probiotic-associated high-titer anti-B in a group A platelet donor as a cause of severe hemolytic transfusion reactions. Transfusion. 2009;49(9):1845-1849.
• 4. Wang Z, Liu L, Ji J et al. ABO blood group system and gastric cancer: a case-control study and meta-analysis. Int J Mol Sci. 2012;13(10):13308-13321.
• 5. Thom N, Ritchlin CT, Zhang X, Reveille J, Weisman MH. Prevalence of chronic axial pain, inflammatory back pain, and spondyloarthritis in diagnosed psoriasis. Arthritis Care Res (Hoboken). 2015;67(6):829-835.
• 6. Alinaghi F, Calov M, Kristensen LE et al. Prevalence of psoriatic arthritis in patients with psoriasis: A systematic review and meta-analysis of observational and clinical studies. J Am Acad Dermatol. 2019;80(1): 251-265.
• 7. Barnas JL, Ritchlin CT. Etiology and Pathogenesis of Psoriatic Arthritis. Rheum Dis Clin North Am. 2015; 41(4):643-663.
• 8. Baxter A, Izatt MM, Jasani MK, McAndrew R. The ABO and RH (D) Blood Groups in Rheumatoid Arthritis. Acta Rheumatol Scand [Internet]. 1968;14(1-4):79-82.
• 9. Kornstad AM, Kornstad L, Guldberg D. Blood groups in ankylosing spondylitis. Ann Rheum Dis [Internet]. 1968;27(5):472-473.
• 10. Hargreaves GK, Hellıer FF. The association of psoriasis with blood groups. AMA Arch Derm. 1958;78(4):438-439.
• 11. Mohammad Shahidi D, Atefeh G, Shima Y. ABO blood group antigens in patients with psoriasis and pemphigus vulgaris. Iran J Dermatology [Internet]. 2015;18(1):16-19.
• 12. Madland TM, Apalset EM, Johannessen AE, Rossebö B, Brun JG. Prevalence, disease manifestations, and treatment of psoriatic arthritis in Western Norway. J Rheumatol. 2005;32(10):1918-1922.
• 13. Taylor W, Gladman D, Helliwell P, Marchesoni A, Mease P, Mielants H. Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum. 2006;54(8): 2665-2673.
• 14. Husted JA, Thavaneswaran A, Chandran V, Gladman DD. Incremental effects of comorbidity on quality of life in patients with psoriatic arthritis. J Rheumatol. 2013;40(8):1349-1356.
• 15. Krawczyk-Wasielewska A, Skorupska E, Samborski W. Sacroiliac joint pain as an important element of psoriatic arthritis diagnosis. Postep dermatologii i Alergol. 2013;30(2):108-112.
• 16. Baek HJ, Yoo CD, Shin KC et al. Spondylitis is the most common pattern of psoriatic arthritis in Korea. Rheumatol Int. 2000;19(3):89-94.
• 17. Moll JM, Wright V. Psoriatic arthritis. Semin Arthritis Rheum. 1973;3(1):55-78.
• 18. Kaeley GS, Eder L, Aydin SZ, Gutierrez M, Bakewell C. Dactylitis: A hallmark of psoriatic arthritis. Semin Arthritis Rheum. 2018;48(2):263-273.
• 19. Zisman D, Eder L, Elias M et al. Clinical and demographic characteristics of patients with psoriatic arthritis in northern Israel. Rheumatol Int. 2012;32(3):595-600.
• 20. Mao Y, Yang W, Qi Q et al. Blood groups A and AB are associated with increased gastric cancer risk: evidence from a large genetic study and systematic review. BMC Cancer. 2019;19(1):164.
• 21. El Jellas K, Hoem D, Hagen KG et al. Associations between ABO blood groups and pancreatic ductal adenocarcinoma: influence on resection status and survival. Cancer Med. 2017;6(7):1531-1540.
• 22. Oguz A, Ünal D, Taşdemir A et al. Lack of any association between blood groups and lung cancer, independent of histology. Asian Pacific J Cancer Prev. 2013;14(1):453-456.
• 23. Kornstad Anne M, Kornstad Leif GD. Blood Groups in Rheumatoid Arthritis. Nature. 1965;206 (4986):836-837.
• 24. Bauer K. Evidence for a protective influence of blood group A phenotype on X-ray signs of ankylosing spondylitis in HLA-B27 positives. Dis Markers. 1987;5(3):187-188.
• 25. Çildağ S, Kara Y, Şentürk T. ABO blood groups and rheumatic diseases. Eur J Rheumatol. 2017;4(4):250-253.
• 26. Cid E, Yamamoto M, Yamamoto F. Blood group ABO gene-encoded A transferase catalyzes the biosynthesis of FORS1 antigen of FORS system upon Met69Thr/Ser substitution. Blood Adv. 2018;2(12):1371-1381.
• 27. Melzer D, Perry JRB, Hernandez D et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet. 2008;4(5):e1000072.
• 28. Zhu J, Qu H, Chen X, Wang H, Li J. Single nucleotide polymorphisms in the tumor necrosis factor-alpha gene promoter region alter the risk of psoriasis vulgaris and psoriatic arthritis: a meta-analysis. PLoS One. 2013;8(5):e64376.