COVID-19 Hastalarında RT-PCR CT Değerleri ile Toraks BT Şiddet Skoru Arasındaki İlişki

Year 2025, Volume: 9 Issue: 1, 62 - 67, 21.04.2025

Altan Akıneden , Cemal Çiçek , Selçuk Türkel , Nimet Büşra Kararmaz , Deniz Özkan

https://doi.org/10.46332/aemj.1450874

Abstract

Amaç: Bu çalışmada, viral yük hakkında bilgi veren RT-PCR Cycles Threshold (Ct) değerleri ile akciğer tutulumunu göstermek için kullanılan Bilgisayarlı Tomografi şiddet skoru (BTŞS) arasındaki ilişkinin araştırması amaçlandı.

Araçlar ve Yöntem: 1 Ocak 2021 ile 31 Kasım 2021 tarihleri arasında akciğer oskültasyon bulguları ve/veya posteroanterior akciğer grafisinde şüpheli bulguları olan ve RT-PCR testi pozitif çıkan toplam 162 hasta çalışmaya dahil edilmiştir. Olguların viral yükleri, akciğer tutulumu ve mortalite oranları hastaneye yatırıldıkları birimlere göre analiz edildi. Ayrıca, COVID-19, BTŞS, RT-PCR Ct viral yük değerleri ve yaşa eşlik eden komorbid hastalıklar arasındaki korelasyon incelendi.

Bulgular: BTŞS yaş ile pozitif ve anlamlı bir korelasyon göstermiştir (p=0.017). İstatistiksel analiz, viral yük ile torasik tutulum arasında anlamlı bir korelasyon olmadığını ortaya koymuştur (p=0.663).

Sonuç: Bu çalışmaya göre, COVID-19 hastalığının tanısında önemli bir yer tutan RT-PCR Ct değerleri ile toraks BT tutulumu arasında anlamlı bir korelasyon bulunmazken, akciğer tutulumu prevalansı ve olguların ölüm oranı yaşla birlikte artmıştır. Ayrıca, CT-CS skoru ile yaş arasında anlamlı bir korelasyon gözlenmiştir. Bu bulgular, bu alanda gelecekte yapılacak derinlemesine araştırmaların önünü açarak konunun daha iyi anlaşılmasını sağlayacaktır.

Keywords

bilgisayarlı tomografi , COVID-19 , tomografi , torasik tutulum , viral yük

Relationship between RT-PCR Threshold Cycle Values and Thorax CT Severity Score in COVID-19 Patients

Abstract

Purpose: In this study, we aimed to investigate the relationship between RT-PCR Cycles Threshold (Ct) values, which provide information about the viral load, and CT severity score (CTSS), which is used to demonstrate lung involvement.

Materials and Methods: Between January 1, 2021 and November 30, 2021, a total of 162 patients with lung auscultation findings and/or suspicious findings on posteroanterior chest radiography, along with a positive RT-PCR test, were included in the study. Viral loads, lung involvement, and mortality rates of the cases were analyzed based on the units in which they were hospitalized. Additionally, we investigated the correlation between comorbid diseases associated with COVID-19, CTSS (CT severity score), RT-PCR Ct viral load values, and age.

Results: The CTSS showed a positive and significant correlation with age (p=0.017). Statistical analysis revealed no significant correlation between viral load and thoracic involvement (p=0.663).

Conclusion: According to the present study, no significant correlation was found between RT-PCR Ct values, which play a crucial role in the diagnosis of COVID-19, and thoracic CT involvement. However, the prevalence of lung involvement and the mortality rate of the cases increased with age. Additionally, a significant correlation was observed between the CT severity score (CT-SS) and age. These findings pave the way for future in-depth research in this field, fostering a better understanding of the subject matter.

Keywords

computed tomography , COVID-19 , thoracic involvement , tomography , viral load

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