Review

Biological activities of royal jelly: a mini-review

Volume: 3 Number: 1 June 30, 2022
EN

Biological activities of royal jelly: a mini-review

Abstract

Royal jelly is a bee product made by cephalic glands of nurse bees that has been utilized in medicine for ages because of its unique therapeutic properties. Proteins, royalisin, jelleins, fatty acids, and 10-hydroxy-2-decenoic acid are among the bioactive components found in royal jelly. There are many studies vouch that royal jelly has antioxidant, antimicrobial, anticancer, fertilization, wound-healing, anti-aging, insulin-like, antimutagenic, antidiabetic, anti-inflammatory potentials. The bioactive components it contains are primarily responsible for these functions. This study is aimed to review the biological activities of royal jelly.

Keywords

References

  1. [1] L. Shen, W. Zhang, F. Jin, L. Zhang, Z. Chen, et al., “Expression of recombinant AccMRJP1 protein from royal jelly of Chinese honeybee in Pichia pastoris and its proliferation activity in an insect cell line”, Journal of Agricultural and Food Chemistry, vol. ED-58 pp. 9190-9197, 2010.
  2. [2] M. H. Alu’datt, T. Rababah, H. A. Sakandar, M. Imran, N. Mustafa, et al., “Fermented food-derived bioactive compounds with anticarcinogenic properties: Fermented royal jelly as a novel source for compounds with health benefits”, in Anticancer Plants: Properties and Application, Ed. Singapore: Springer, 2018, pp. 141-165.
  3. [3] L. I. Bărnuţiu, L. A. Mărghitaş, D. S. Dezmirean, C. M. Mihai and O. Bobiş, “Chemical composition and antimicrobial activity of royal jelly-review”, Scientific Papers Animal Science and Biotechnologies, vol. ED-44, pp. 67-72, 2011.
  4. [4] J. Schmitzova, J. Klaudiny, S. Albert, W. Schroder, W. Schreckengost et al., “A family of major royal jelly proteins of the honey bee Apis Mellifera L.”, Cell Molecular Life Science, vol. ED-54, pp. 1020-1030, 1998.
  5. [5] D. Vucevic, E. Melliou, S. Vasilijic, S. Gasic, P. Ivanovski et al., “Fatty acids isolated from royal jelly modulate dendritic cell-mediated immune response in vitro”, International Immunopharmacology, vol. ED-7, pp. 1211–1220, 2007.
  6. [6] H. Oka, Y. Emori, N. Kobayashi, Y. Hayashi, K. Nomoto, “Suppression of allergic reactions by royal jelly in association with the restoration of macrophage function and the improvement of Th1/Th2 cell responses”, International Immunopharmacology, vol. ED-1, pp. 521-532, 2001.
  7. [7] J. Zhou, X. Xue, Y. Li, J. Zhang, J. Zhao “Optimized determination method for trans-10-hydroxy-2-decenoic acid content in royal jelly by high-performance liquid chromatography with an internal standard”, Journal of AOAC International, vol. ED-90, pp. 244-249, 2007.
  8. [8] A. Bozorgi, S. Khazaei, A. Khademi and M. Khazaei, “Natural and herbal compounds targeting breast cancer, a review based on cancer stem cells” Iranian Journal of Basic Medical Sciences, vol. ED-23, pp. 970, 2020.

Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Review

Authors

Publication Date

June 30, 2022

Submission Date

February 22, 2022

Acceptance Date

May 6, 2022

Published in Issue

Year 2022 Volume: 3 Number: 1

EndNote
Civelek İ (June 1, 2022) Biological activities of royal jelly: a mini-review. Anatolian Journal of Biology 3 1 1–8.