Abstract
Fibromiyalji kronik yaygın ağrı ile karakterize multisistemik bir hastalıktır. Tedavisinde kür olmamakla birlikte hasta eğitimi, aerobik egzersizler, kognitif davranışsal terapi, farmakolojik tedavilerin (serotonin noradrenalin geri alım inhibitörleri [Ör,duloksetin,milnasipran] ve alfa 2-delta reseptör ligandı [Ör,pregabalin]) kombine multidisipliner ekip yaklaşımı ile kullanımı hastalarda semptomların ve özellikle fonksiyonun düzelmesine yardımcı olabilir. Dopamin agonistleri (pramipeksol), tramadol, diğer opioidler ve kannabinoidlerin (nabilon) ile de bazı başarılı sonuçlar gösterilmiştir. Tamamlayıcı tedaviler kullanarak daha fazla kanıta dayalı çalışmalara ihtiyaç vardır.
Keywords
References
- 1. Bhusal S, Diomampo S, Magrey MN. Clinical utility, safety, and efficacy of pregabalin in the treatment of fibromyalgia. Drug Healthc Patient Saf. 2016;8:13-23.
- 2. Wolfe F, Ross K, Anderson J, Russell IJ. Aspects of fibromyalgia in the general population: sex, pain threshold, and fibromyalgia symptoms. J Rheumatol. 1995;22:151-6.
- 3. Smith HS, Harris R, Clauw D. Fibromyalgia: an afferent processing disorder leading to a complex pain generalized syndrome. Pain Physician. 2011;14:217-45.
- 4. Häuser W, Thieme K, Turk DC. Guidelines on the management of fibromyalgia syndrome - a systematic review. Eur J Pain. 2010;14:5-10.
Abstract
Fibromyalgia is a multisystem disorder characterized by widespread pain. Although there is no known cure for fibromyalgia, multidisciplinary team efforts using combined treatment approaches, including patient education, aerobic exercise, cognitive behavioral therapy, and pharmacologic therapies (serotonin norepinephrine reuptake inhibitors [eg, duloxetine, milnacipran] and alpha 2-delta receptor ligands [eg, pregabalin]) may improve symptoms as well as function of patients with fibromyalgia. Some success has been shown with dopamine agonists (pramipexole), tramadol, other opioids and cannabinoids (nabilone). Further evidence-based trials using complementary treatments are needed.
Keywords
References
- 1. Bhusal S, Diomampo S, Magrey MN. Clinical utility, safety, and efficacy of pregabalin in the treatment of fibromyalgia. Drug Healthc Patient Saf. 2016;8:13-23.
- 2. Wolfe F, Ross K, Anderson J, Russell IJ. Aspects of fibromyalgia in the general population: sex, pain threshold, and fibromyalgia symptoms. J Rheumatol. 1995;22:151-6.
- 3. Smith HS, Harris R, Clauw D. Fibromyalgia: an afferent processing disorder leading to a complex pain generalized syndrome. Pain Physician. 2011;14:217-45.
- 4. Häuser W, Thieme K, Turk DC. Guidelines on the management of fibromyalgia syndrome - a systematic review. Eur J Pain. 2010;14:5-10.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Review |
| Authors | |
| Publication Date | March 31, 2017 |
| Acceptance Date | July 20, 2016 |
| Published in Issue | Year 2017 |
