Abstract
Human Leukocyte Antigen (HLA) is under the control of a gene region, which is called Major Histocompatibility Complex (MHC) Gene Region. This region consists of three main groups which are the MHC Class I (HLA-I, -B, -C, -E, -F, -G), MHC Class II (HLA-DR, -DP, -DQ, -DO, DN) and MHC Class III (C2, C4A, C4B, PF, TNF- a, b) antigens. Here is to give a brief overview of HLA and HAL typing.
References
- Roitt IM, Delves PJ. Roitt’s Essential Immunology, 10th Edition. New York, Blackwell Science, 200 Roth DB. T cells and MHC. In Immunology, 7th Edition (Eds D Male, J Brostoff, DB Roth, I RoithI):105-24. New York, Elsevier, 2006.
- Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA et al. Nomenclature for factors of the HLA System. Hum Immunol. 2005; 66:571-636.
Abstract
İnsan Lökosit Antijenleri (HLA) \\\"Majör Histokompatibilite kompleksi-Major Histocompatibility Complex Gen Region (MHC)\\\" adı verilen bir gen bölgesinin kontrolü altındadır. Üç ana gruba ayrılan bu bölgede MHC Sınıf-I (HLA-A, -B, -C, -E, -F, -G), MHC Sınıf-II (HLA-DR, -DP, -DQ, -DO, -DN) ve MHC Sınıf-III (C2, C4A, C4B, PF, TNF- a, b) antijenleri yer almaktadır. Burada HLA ve HLA tiplendirimi ile ilgili özet bilgilerin sunulması amaçlanmıştır.
References
- Roitt IM, Delves PJ. Roitt’s Essential Immunology, 10th Edition. New York, Blackwell Science, 200 Roth DB. T cells and MHC. In Immunology, 7th Edition (Eds D Male, J Brostoff, DB Roth, I RoithI):105-24. New York, Elsevier, 2006.
- Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA et al. Nomenclature for factors of the HLA System. Hum Immunol. 2005; 66:571-636.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Review |
| Authors | |
| Publication Date | October 30, 2014 |
| Published in Issue | Year 2014 |
