Diyabetik Hayvan Modelleri ve Önemi

Zehra Çiçek; Zehra Gül Koçaklı; Kübra Akıllıoğlu; Ayşe Doğan

doi:10.17827/aktd.357580

EN TR

Diyabetik Hayvan Modelleri ve Önemi

Abstract

Diabetes mellitus günümüzde sıklığı, sebep olduğu komplikasyonlar ve tedavi maliyeti nedeniyle tüm dünyada önemi gittikçe artan bir sağlık problemi olarak karşımıza çıkmaktadır. Diğer bilimsel çalışmalarda olduğu gibi diyabet araştırmalarında da çeşitli hayvan modelleri kullanılmaktadır. Tip 1 ve tip 2 diabet patolojisinin altında yatan mekanizmaları ortaya çıkarmak, komplikasyonlarını önlemek ve yeni ilaç denemeleri için deneysel hayvan modelleri geliştirilmektedir. Birçok hayvan türünde kimyasal bazı ilaçlarla (streptozotosin ve alloksan), cerrahi olarak pankreasın çıkarılmasıyla (pankreatektomi) ve genetik yöntemlerle tip 1 ve tip 2 diyabet modeli oluşturulabilmektedir. Bu derlemede, diyabetik hayvan modelleri ve önemi hakkında son gelişmeler ışığında bilgiler verilmiştir.

Keywords

Diyabetes mellitus,hayvan modelleri

References

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Zehra Çiçek ^*
Çukurova Üniversitesi, Tıp Fakültesi, Fizyoloji AD
Türkiye

Zehra Gül Koçaklı This is me
Türkiye

Kübra Akıllıoğlu
Türkiye

Ayşe Doğan This is me
Türkiye

Publication Date

September 30, 2018

Submission Date

November 24, 2017

Acceptance Date

February 12, 2018

Published in Issue

Year 2018 Volume: 27 Number: 3

DOI

https://doi.org/10.17827/aktd.357580

IZ

https://izlik.org/JA55SX69FJ

APA

Çiçek, Z., Koçaklı, Z. G., Akıllıoğlu, K., & Doğan, A. (2018). Diyabetik Hayvan Modelleri ve Önemi. Arşiv Kaynak Tarama Dergisi, 27(3), 311-327. https://doi.org/10.17827/aktd.357580

AMA

1.Çiçek Z, Koçaklı ZG, Akıllıoğlu K, Doğan A. Diyabetik Hayvan Modelleri ve Önemi. Arşiv Kaynak Tarama Dergisi. 2018;27(3):311-327. doi:10.17827/aktd.357580

Chicago

Çiçek, Zehra, Zehra Gül Koçaklı, Kübra Akıllıoğlu, and Ayşe Doğan. 2018. “Diyabetik Hayvan Modelleri Ve Önemi”. Arşiv Kaynak Tarama Dergisi 27 (3): 311-27. https://doi.org/10.17827/aktd.357580.

EndNote

Çiçek Z, Koçaklı ZG, Akıllıoğlu K, Doğan A (September 1, 2018) Diyabetik Hayvan Modelleri ve Önemi. Arşiv Kaynak Tarama Dergisi 27 3 311–327.

IEEE

[1]Z. Çiçek, Z. G. Koçaklı, K. Akıllıoğlu, and A. Doğan, “Diyabetik Hayvan Modelleri ve Önemi”, Arşiv Kaynak Tarama Dergisi, vol. 27, no. 3, pp. 311–327, Sept. 2018, doi: 10.17827/aktd.357580.

ISNAD

Çiçek, Zehra - Koçaklı, Zehra Gül - Akıllıoğlu, Kübra - Doğan, Ayşe. “Diyabetik Hayvan Modelleri Ve Önemi”. Arşiv Kaynak Tarama Dergisi 27/3 (September 1, 2018): 311-327. https://doi.org/10.17827/aktd.357580.

JAMA

1.Çiçek Z, Koçaklı ZG, Akıllıoğlu K, Doğan A. Diyabetik Hayvan Modelleri ve Önemi. Arşiv Kaynak Tarama Dergisi. 2018;27:311–327.

MLA

Çiçek, Zehra, et al. “Diyabetik Hayvan Modelleri Ve Önemi”. Arşiv Kaynak Tarama Dergisi, vol. 27, no. 3, Sept. 2018, pp. 311-27, doi:10.17827/aktd.357580.

Vancouver

1.Zehra Çiçek, Zehra Gül Koçaklı, Kübra Akıllıoğlu, Ayşe Doğan. Diyabetik Hayvan Modelleri ve Önemi. Arşiv Kaynak Tarama Dergisi. 2018 Sep. 1;27(3):311-27. doi:10.17827/aktd.357580

Cited By

How to create an experimental diabetes mellitus model?

Pharmacia

https://doi.org/10.3897/pharmacia.70.e96028

This journal is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Diabetic Animal Models and Its Importance

Abstract

Keywords

Diyabetik Hayvan Modelleri ve Önemi

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

﻿How to create an experimental diabetes mellitus model?

How to create an experimental diabetes mellitus model?