Physiological Basis of Attention Deficit Hyperactivity Disorder

Year 2010, Volume: 19 Issue: 1, 1 - 11, 01.03.2010

Nurcihan Kiriş Seçil Binokay

Abstract

Attention-deficit hyperactivity disorder (ADHD) is a childhood psychiatric disorder characterized by inattention, impulsivity, and overactivity. The findings obtained from studies in the fields of neuropsychology, neuroimaging and neurophysiology have supported that ADHD patients have abnormalities of brain structure and function. The aim of this article is to examine the underlying neuroanatomic and neurophysiological characteristics of ADHD. This review provide an evidence-based overview of ADHD, including in dysregulation of frontal-subcortical-cerebellar dopaminergic circuits with structural brain abnormalities.

Keywords

Attention Deficit Hyperactivity Disorder, Etiology

Dikkat Eksikliği ve Hiperaktivite Bozukluğunun Fizyolojik Temelleri

Abstract

Dikkat Eksikliği Hiperaktivite Bozukluğu (DEHB), dikkatsizlik, impulsivite ve hiperaktivite ile karakterize bir çocukluk çağı psikiyatrik bozukluktur. Nörogörüntüleme, nöropsikoloji ve nörofizyoloji alanlarında yapılan çok sayıda araştırma bulguları DEHB olan hastaların beyin yapısı ve işlevlerinde anormallikler olduğunu desteklemektedir. Bu makalenin amacı DEHB'nun altında yatan nöroanatomik ve nörofizyolojik özellikleri incelemektir. Bu derleme, DEHB'nda yapısal beyin anormallikleri ile birlikte frontal-subkortikal-serebellar dopaminerjik devrelerdeki düzensizliği içeren araştırma bulgularını gözden geçirmeyi sağlamaktadır.

Keywords

Dikkat Eksikliği ve Hiperaktivite Bozukluğu, Etyoloji

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