Fibromiyaljide Farmakolojik Tedavi

Year 2017, Volume: 26 Issue: 1, 124 - 141, 31.03.2017

Ayhan Aşkın , Ayten Özkan

https://doi.org/10.17827/aktd.280530

Cited By: 1

Abstract

Fibromiyalji kronik yaygın ağrı ile karakterize multisistemik bir hastalıktır. Tedavisinde kür olmamakla birlikte hasta eğitimi, aerobik egzersizler, kognitif davranışsal terapi, farmakolojik tedavilerin (serotonin noradrenalin geri alım inhibitörleri [Ör,duloksetin,milnasipran] ve alfa 2-delta reseptör ligandı [Ör,pregabalin]) kombine multidisipliner ekip yaklaşımı ile kullanımı hastalarda semptomların ve özellikle fonksiyonun düzelmesine yardımcı olabilir. Dopamin agonistleri (pramipeksol), tramadol, diğer opioidler ve kannabinoidlerin (nabilon) ile de bazı başarılı sonuçlar gösterilmiştir. Tamamlayıcı tedaviler kullanarak daha fazla kanıta dayalı çalışmalara ihtiyaç vardır.

Keywords

Fibromiyalji, farmakolojik tedavi, ilaç

Pharmacological Treatment in Fibromyalgia

Abstract

Fibromyalgia is a multisystem disorder characterized by widespread pain. Although there is no known cure for fibromyalgia, multidisciplinary team efforts using combined treatment approaches, including patient education, aerobic exercise, cognitive behavioral therapy, and pharmacologic therapies (serotonin norepinephrine reuptake inhibitors [eg, duloxetine, milnacipran] and alpha 2-delta receptor ligands [eg, pregabalin]) may improve symptoms as well as function of patients with fibromyalgia. Some success has been shown with dopamine agonists (pramipexole), tramadol, other opioids and cannabinoids (nabilone). Further evidence-based trials using complementary treatments are needed. 

Keywords

: Fibromyalgia, pharmacological treatment, drug

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