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Hyperemesis Gravidarum

Yıl 2017, Cilt: 26 Sayı: 3, 269 - 296, 30.09.2017

Mehmet Bülbül , Mustafa Kaplanoğlu , Emel Arslan Yıldırım Berna Yılmaz

https://doi.org/10.17827/aktd.303579
Cited By: 8

Öz

Hyperemesis gravidarum is most commonly seen in the first trimester. Weight loss usually accompanies vomiting and it is less common that the pregnancy-related nausea (0.3-3.6%). Environmental factors and genetic predisposition may play a role in the etiology. Furthermore it is thought that the increased placental load and elevated β-hCG levels also play a role in development of hyperemesis gravidarum. The psychological state of the patient might also aggravate the disease. Hyperemesis gravidarum is diagnosed clinically. This situation will threaten the woman’s life besides having potential negative effects on the newborn health if it is not treated properly. The first step of treatment is diet and life style change. Intravenous hydration, electrolyte supplmentation and antiemetics can be used safely and efficiently..

Anahtar Kelimeler

Hyperemesis gravidarum etiology treatment

Kaynakça

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Hiperemezis Gravidarum

Yıl 2017, Cilt: 26 Sayı: 3, 269 - 296, 30.09.2017

Mehmet Bülbül , Mustafa Kaplanoğlu , Emel Arslan Yıldırım Berna Yılmaz

https://doi.org/10.17827/aktd.303579
Cited By: 8

Öz

Hiperemezis gravidarum sıklıkla ilk trimesterde görülür. Kilo kaybı kusma ile birlikte seyreder ve gebeliğe bağlı bulantı-kusmaya göre daha nadirdir (%0,3-3.6). Çevresel faktörlerle genetik yatkınlığın etiyolojide rol oynadığı düşünülmektedir. Ayrıca plasental yük ve yüksek β-hCG düzeyleri de hiperemesis gravidarum gelişiminde rol oynar. Kişinin psikolojik yapısı da hastalığın seyrini değiştirebilir. Etiyolojide bunların dışında birçok faktör suçlansa da kanıtlanmış kesin bilgi yoktur. Hiperemesis gravidarum tanısı klinik olarak konulur. Uygun şekilde tedavi edilmediğinde anne ve bebeğin hayatını olumsuz etkileyebilir. Tedavide ilk basamak diyet ve yaşam tarzı değişikliğidir. İntravenöz hidrasyon, elektrolit desteği ile antiemetikler güvenli ve etkili olarak tedavide kullanılabilir.

Anahtar Kelimeler

Hiperemezis gravidarum Etiyoloji Tedavi

Kaynakça

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  • 122. Smith C, Crowther C, Willson K, Hotham N, McMillian V. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol. 2004;103(4):639-45.
  • 123. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai. 2007;90(1):15-20.
  • 124. Ensiyeh J, Sakineh MA. Comparing ginger and vitamin B6 for the treatment of nausea and vomiting in pregnancy: a randomised controlled trial. Midwifery. 2009;25(6):649-53.
  • 125. Guttuso T Jr, Roscoe J, Griggs J. Effect of gabapentin on nausea induced by chemotherapy in patients with breast cancer. Lancet. 2003b;361:1703–1705
  • 126. Guttuso T Jr. Gabapentin's anti-nausea and anti-emetic effects: a review. Exp Brain Res. 2014;232(8):2535-9.
  • 127. Guttuso T Jr, Shaman M, Thornburg LL. Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy. Eur J Obstet Gynecol Reprod Biol. 2014;181:280-3.
  • 128. Sahakian V, Rouse D, Sipes S, Rose N, Niebyl J. Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstet Gynecol. 1991;78(1):33-6.
  • 129. Vutyavanich T, Wongtra-ngan S, Ruangsri R. Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol. 1995;173(3 Pt 1):881-4.
  • 130. Vaisman N, Kaidar R, Levin I, Lessing JB. Nasojejunal feeding in hyperemesis gravidarum--a preliminary study. Clin Nutr. 2004;23(1):53-7.
  • 131. Stokke G, Gjelsvik BL, Flaatten KT, Birkeland E, Flaatten H, Trovik J. Hyperemesis gravidarum, nutritional treatment by nasogastric tube feeding: a 10-year retrospective cohort study. Acta Obstet Gynecol Scand. 2015;94(4):359-67.
  • 132. Puangsricharern A, Mahasukhon S. Effectiveness of auricular acupressure in the treatment of nausea and vomiting in early pregnancy. J Med Assoc Thai. 2008;91(11):1633-8
  • 133. Matthews A, Dowswell T, Haas DM, Doyle M, O'Mathúna DP. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2010 Sep 8;(9):CD007575.
  • 134. Smith C, Crowther C, Beilby J. Acupuncture to treat nausea and vomiting in early pregnancy: a randomized controlled trial. Birth. 2002;29(1):1-9.
  • 135. Knight B, Mudge C, Openshaw S, White A, Hart A. Effect of acupuncture on nausea of pregnancy: a randomized, controlled trial. Obstet Gynecol. 2001;97(2):184-8.
  • 136. Matthews A, Haas DM, O'Mathúna DP, Dowswell T, Doyle M. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2014 Mar 21;3:CD007575.
  • 137. Henker FO 3rd. Psychotherapy as adjunct in treatment of vomiting during pregnancy. South Med J. 1976;69(12):1585-7.
  • 138. Zechnich R, Hammer T. Brief psychotherapy for hyepremesis gravidarum. Am Fam Physician. 1982;26(5):179-81.
  • 139. http://www.uptodate.com/home/grading-guide.
Toplam 139 adet kaynakça vardır.

Ayrıntılar

Konular Sağlık Kurumları Yönetimi
Bölüm Derleme
Yazarlar

Mehmet Bülbül

Mustafa Kaplanoğlu

Emel Arslan Yıldırım Bu kişi benim

Berna Yılmaz Bu kişi benim

Yayımlanma Tarihi 30 Eylül 2017
Kabul Tarihi 9 Ocak 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 26 Sayı: 3

Kaynak Göster

AMA Bülbül M, Kaplanoğlu M, Arslan Yıldırım E, Yılmaz B. Hiperemezis Gravidarum. aktd. Eylül 2017;26(3):269-296. doi:10.17827/aktd.303579

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