Ventilator-Induced Diaphragmatic Dysfunction: Pathogenesis, Diagnosis and New Therapeutics

Yıl 2020, Cilt: 29 Sayı: 3, 199 - 208, 30.09.2020

Esra Çakır , İşil Özkoçak Turan

Öz

The diaphragm is the main inspiratory muscle and the diaphragm function is of vital importance for optimal breathing. Diaphragm dysfunction may accompany various systemic neuromuscular diseases and increase the risk of death. Furthermore, the use of mechanical ventilation (MV) therapy leads to ventilator-induced diaphragm dysfunction (VIDD). Recently, VIDD has been shown to be associated with the severity of weaning from the ventilator in most critical patients. This review summarizes the pathogenesis, diagnosis and treatment of VIDD.

Anahtar Kelimeler

Ventilator-induced diaphragm dysfunction, mechanical ventilation, diaphragm

Proje Numarası

yok

Ventilatör İlişkili Diyafram Disfonksiyonu: Patogenez, Tanı ve Yeni Tedaviler

Öz

Diyafram, ana
inspiryum kasıdır ve optimal solunum için diyafram fonksiyonunun hayati önemi
vardır. Diyafram yetmezliği, çeşitli sistemik nöromüsküler hastalıklara eşlik edebilir
ve ölüm riskini artırır. Ayrıca, mekanik ventilasyon (MV) kullanımı, ventilatör
ilişkili diyafram disfonksiyonuna (VİDD) yol açar. Son zamanlarda, VİDD’nin,
kritik hastaların çoğunda olup, ventilatörden ayrılma zorlukları ile ilişkili
olduğu gösterilmiştir. Bu derleme, VİDD patogenezini, tanısını ve tedavisini
özetlemektedir.

Anahtar Kelimeler

ventilatör ilişkili diyafram disfonksiyonu, mekanik ventilasyon, diyafram

Destekleyen Kurum

yok

Proje Numarası

yok

Teşekkür

yok

Kaynakça

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