Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr.

Year 2017, Volume: 3 Issue: 1, 31 - 42, 15.06.2017

Muhammet Şamil Yağlıoğlu Gökhan Abay İbrahim Demirtaş Ayşe Şahin Yağlıoğlu

https://doi.org/10.26672/anatolianbryology.317785

Cited By: 8

Abstract

The paper presents information about the phytochemical analysis,
antiproliferative and cytotoxic activities of Rhytidiadelphus triquetrus and Tortella tortuosa extracts.
The cytotoxic activities of some extracts shows highest antiproliferative
activities were detected with Lactate Dehydrogenase Leakage Assay.
Sixteen components obtained from hexane extracts were determined by GC/MS.
Palmitic acid was identified as the main component. The phenolic components of
the other extracts were determined by HPLC-TOF/MS. 4-hydroxy benzoic acid,
salicylic acid, gallic acid, caffeic acid, and gensitic acid were detected as
the main components in all extracts. The hexane, chloroform, ethyl acetate
extracts of studied mosses and the EtOAc and hexane extracts of R. triquetrus showed
statistically significant antiproliferative activities.

Keywords

Anticancer; cytotoxic; C6 cancer cell; HeLa cancer cell; mosses

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