Akut Renal Yetmezliği Olan Hastalarda QT Dispersiyon Varlığının ve Elektrolit Dengesizliği ile İlişkisinin Araştırılması

Year 2021, Volume: 4 Issue: 4, 132 - 137, 29.12.2021

Egemen Noyın Yeşim İşler , Halil Kaya , Melih Yüksel

https://doi.org/10.54996/anatolianjem.982305

Abstract

Amaç: Bu çalışma, akut renal yetmezliği (ARY) olan hastalarda QT dispersiyonu ile elektrolit dengesizliği arasındaki ilişkiyi ve QT dispersiyonunun ARY şiddeti ile ilişkili olup olmadığını araştırmayı amaçlamaktadır.

Gereç ve Yöntemler: Üçüncü basamak acil serviste 3 aylık bir süre içinde başvuran 18 yaş üstü toplam 400 hasta prospektif olarak incelendi. Katılımcıların 200'ü ARY tanısı alırken, 200'ü kontrol grubundaydı. QT dispersiyonu varlığı, potasyum değerleri, yaş ve cinsiyet verileri ve kan üre nitrojen (BUN)/Kreatinin(Cr) oranı parametreleri incelendi ve karşılaştırmalar yapıldı.

Bulgular: ARY tanısı alan hastaların yaş ortalaması 55.9±16.7 yıl, kontrol grubunda ise 54,8±18,2 idi. ARY grubunda QT dispersiyonu anlamlı olarak daha yüksekti (p<0,001). Potasyum değeri QT dispersiyonlu ARY grubunda 4,9±0,8 mEq/L iken kontrol grubunda 4,3±0,5 mEq/L idi. QT dispersiyonu olan ARY hastalarında potasyum değerleri anlamlı olarak yüksekti (p<0,001). ARY'li hastalar QT dispersiyonu açısından karşılaştırıldığında yaş, cinsiyet, elektrolit dengesizlikleri ve BUN/Cr oranları arasında anlamlı fark bulunmadı.

Sonuç: Yaş ve cinsiyet hastalarda QT dispersiyonu için prediktif parametreler değildir. QT dispersiyonu olan ARY hastalarında hiperkalemi anlamlı olarak daha yüksektir. Yüksek BUN/Cr oranı, ARY'li hastalarda QT dispersiyonunun varlığını öngören bir parametre değildir. ARY hastalarında QT dispersiyonunun sıklığı yüksektir. ARY takibinde QT dispersiyonunun klinisyene olası komplikasyonları ve mortaliteyi öngörmede yardımcı olabileceğini düşünüyoruz.

Keywords

Acil servis, akut renal yetmezlik, elektrolit imbalansı, QT dispersiyonu

Investigation of the Presence of QT Dispersion and its Relationship with Electrolyte Imbalance in Patients with Acute Kidney Injury

Abstract

Aim: This study aims to investigate the relationship between QT dispersion and electrolyte imbalance in patients with acute kidney injury (AKI), and whether QT dispersion is associated with the severity of AKI.

Material and Methods: A total of 400 patients over the age of 18 presenting to a tertiary emergency department over a 3-month period were prospectively examined. While 200 of the participants were diagnosed with AKI, 200 were in the control group. Presence of QT dispersion, potassium values, age and sex data, and blood urea nitrogen (BUN) /Creatinine (Cr) ratio parameters were examined and comparisons were made.

Results: The mean age of patients diagnosed with AKI was 55.9±16.7 years, while it was 54.8±18.2 in the control group. QT dispersion was significantly higher in the AKI group (p<0.001). While the potassium value was 4.9±0.8 mEq/L in the AKI group with QT dispersion, it was 4.3±0.5 mEq/L in the control group. Potassium values were significantly higher in AKI patients with QT dispersion (p<0.001). When patients with AKI were compared in terms of QT dispersion, no significant difference was found between age, gender, electrolyte imbalances, and BUN/Cr ratios.

Conclusion: Age and gender are not predictive parameters for QT dispersion in patients. Hyperkalemia is significantly higher in AKI patients with QT dispersion. High BUN/Cr ratio is not a predictive parameter for the presence of QT dispersion in patients with AKI. The frequency of QT dispersion is high in AKI patients. We think that QT dispersion in AKI follow-up may help the clinician predict possible complications and mortality.

Keywords

Emergency medicine, acute kidney injury, electrolyte imbalance, QT dispersion

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