Acil Servise Başvuran COVID-19 Hastalarında Toraks BT ile Ölçülen Pulmoner Arter Çapı ile D Dimer Arasındaki İlişki

Year 2024, Volume: 7 Issue: 1, 15 - 20, 31.03.2024

Necmi Emre Coşkun , Turgay Yılmaz Kılıç , Necmiye Yalçın Ocak , Zeynep Temizyürek Cebeci , Ebru Hasbay

https://doi.org/10.54996/anatolianjem.1409530

Abstract

Amaç: Coronavirüs hastalığı 2019 (COVID-19) salgını, dünya çapında hızla yayılması nedeniyle küresel bir sağlık acil durumu haline geldi. Çalışmamız COVID-19 hastalarında pulmoner arter çapı ile d-dimer arasındaki ilişkiyi değerlendirmiştir.

Gereç ve Yöntemler: Çalışmamıza 15 Mart 2020 ile 31 Kasım 2020 tarihleri arasında acil servisimize başvuran, Uluslararası Hastalık Sınıflandırması 10’a göre tanı kodu U07.3 olan 18 yaş ve üzeri hastalar dahil edildi. Hastaların demografik verileri (yaş, cinsiyet), laboratuvar testleri (polimeraz zincir reaksiyon testi, ddimer düzeyi) ve görüntüleme sonuçları (bilgisayarlı göğüs tomografisi, pulmoner anjiyografi bilgisayarlı tomografisi) tıbbi kayıtları ve hastane elektronik kayıt sistemi kullanılarak retrospektif olarak analiz edildi.

Bulgular: Çalışmaya toplam 1654 hasta dahil edildi. 30 günlük mortalite oranı %13,7 (n=227) idi. 30 günlük mortalite üzerinde en etkili bağımsız değişken 44 yaş ve üstünde olmaktı. Pulmoner arter çapı ve d-dimer düzeyleri hem tipik COVID-19 toraks bilgisayarlı tomografi bulguları olan grupta hem de 30 gün içinde ölen hastalarda daha yüksek bulundu. Ancak literatürden farklı olarak pulmoner embolisi olan ve olmayan hastalar arasında pulmoner arter çapı ve d-dimer düzeyleri açısından anlamlı fark bulunmadı.

Sonuç: Sonuç olarak, COVID-19 hastalarında d-dimer ile pulmoner arter çapı arasında zayıf pozitif bir korelasyon bulundu.

Keywords

COVID-19, d-dimer, pulmoner arter, pulmoner arter çapı

The Relationship Between Pulmonary Artery Diameter Measured by Chest CT and D-Dimer in COVID-19 Patients Admitted to the Emergency Department

Abstract

Aim: The coronavirus disease 2019 (COVID-19) pandemic has become a global health emergency due to its rapid spread worldwide. Our study evaluated the relationship between pulmonary artery diameter and d-dimer in COVID-19 patients.

Material and Methods: Patients aged 18 years and older with International Classification of Diseases 10 diagnosis code U07.3 who were admitted to our emergency department between March 15, 2020, and November 31, 2020, were included in our study. Demographic data (age, sex), laboratory tests (polymerase chain reaction test, d-dimer level), and imaging results (chest computed tomography, computed tomography pulmonary angiography) of the patients were retrospectively analyzed using medical records and the hospital electronic record system.

Results: A total of 1654 patients were included in the study. The 30-day mortality rate was 13.7% (n=227). The most effective independent variable on 30-day mortality was 44 years of age or older. Pulmonary artery diameter and d-dimer levels were found to be higher in both the group with typical COVID-19 chest computed tomography findings and in patients who died within 30 days. However, unlike the literature, there was no significant difference in pulmonary artery diameter and d-dimer levels between patients with and without pulmonary embolism.

Conclusion: In conclusion, we found a weak positive correlation between d-dimer and pulmonary artery diameter in COVID-19 patients.

Keywords

COVID-19, d-dimer, pulmonary artery, pulmonary artery diameter

Ethical Statement

The study was approved by the Ethics Committee of the University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey. (Approval number 2020/13-42).

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