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A Rare Case of Impaired Consciousness, Compartment Syndrome and Rhabdomyolisis Following Local Dermal Exposure to Stinging Nettles (Urtica dioica)

Year 2024, Volume: 7 Issue: 4, 178 - 181, 30.12.2024
https://doi.org/10.54996/anatolianjem.1598496

Abstract

Aim: Nettle (Urtica dioica) is widely used in traditional medicine but is also known for its irritating effects upon dermal contact. While local irritation is common, severe systemic reactions are rarely reported. In this case, we aim to present a patient who developed altered consciousness, rhabdomyolysis, and compartment syndrome following dermal exposure to Urtica dioica.

Case: An eighty-five-year-old female initially presented to the emergency department with localized itching and edema. However, on repeat admission days later, she exhibited confusion, agitation, and significant swelling in her left arm. Laboratory findings revealed rhabdomyolysis, with marked renal dysfunction, elevated creatine kinase, troponin, and inflammatory markers. Imaging ruled out intracranial pathology, and Doppler ultrasonography excluded vascular obstruction. Despite treatment, the patient required long-term care in a palliative setting.

Conclusion: Although Urtica dioica is traditionally known for its medicinal properties, its irritant effects can lead to serious systemic complications following dermal exposure. The findings highlight the potential life-threatening outcomes of a commonly encountered plant, emphasizing the need for awareness and prompt intervention in such cases. Clinicians should consider these risks when managing patients with similar presentations.

Ethical Statement

None.

Supporting Institution

None.

Thanks

None.

References

  • Abi Sleiman M, Younes M, Hajj R, et al. Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials. Int J Mol Sci. 2024;25(13):7501. doi:10.3390/ijms25137501
  • Halder S, Sharma A. A review on Urtica dioica L. World J Pharm Pharm Sci. 2017;6(10).
  • Zeytin AT, Ergün N, Çevik AA, Özçelik H. Altered mental status and delayed serious allergic reaction after drinking the boiled water of nettle (Urtica dioica). Turk J Emerg Med. 2008;8(3):136-138.
  • Cummings AJ, Olsen M. Mechanism of Action of Stinging Nettles. Wilderness Environ Med. 2011;22(2):136-139. doi:10.1016/j.wem.2011.01.001
  • Devkota HP, Paudel KR, Khanal S, et al. Stinging Nettle (Urtica dioica L.): Nutritional Composition, Bioactive Compounds, and Food Functional Properties. Molecules. 2022;27(16). doi:10.3390/molecules27165219
  • Đurović S, Kojić I, Radić D, et al. Chemical Constituents of Stinging Nettle (Urtica dioica L.): AComprehensive Review on Phenolic and Polyphenolic Compounds and Their Bioactivity. Int J Mol Sci. 2024;25(6):3430. doi:10.3390/ijms25063430
  • Northall F. Vegetation, vegetables, vesicles: plants and skin. Emergency Nurse. 2003;11(3):18-23. doi:10.7748/en2003.06.11.3.18.c7656
  • Kolovou G, Cokkinos P, Bilianou H, Kolovou V, Katsiki N, Mavrogeni S. Non-traumatic and non-drug-induced rhabdomyolysis. Archives of Medical Science – Atherosclerotic Diseases. 2019;4(1). doi:10.5114/amsad.2019.90152
  • Batur A. Travmatik Rabdomiyoliz (CRUSH Yaralanması) Yönetimi. Anatolian Journal of Emergency Medicine. 2023;6(1):41-46. doi:10.54996/anatolianjem.1252372.

Isırgan Otu (Urtica dioica) ile Lokal Dermal Maruziyet Sonrası Nadir Görülen Bilinç Bozukluğu, Kompartman Sendromu ve Rabdomiyolizis Vakası

Year 2024, Volume: 7 Issue: 4, 178 - 181, 30.12.2024
https://doi.org/10.54996/anatolianjem.1598496

Abstract

Amaç: Isırgan otu (Urtica dioica) geleneksel tıpta yaygın olarak kullanılır ancak aynı zamanda dermal temasta tahriş edici etkileriyle de bilinir. Lokal tahriş yaygın olsa da şiddetli sistemik reaksiyonlar nadiren bildirilir. Bu vakada, Urtica dioica'ya dermal maruziyet sonrası bilinç bozukluğu, rabdomiyoliz ve kompartman sendromu ile gelen hastayı sunmayı amaçladık.

Olgu: Seksen beş yaşında kadın hasta acile ilk lokalize kaşıntı ve ödem şikayetiyle başvurdu. Ancak tekrarlayan başvurusunda günler sonra bilinç bulanıklığı, ajitasyon ve sol kolda belirgin şişlik şikayetleri mevcut olup, laboratuvar bulguları, önemli böbrek bozukluğunun yanı sıra yüksek kreatinin kinaz, troponin ve inflamatuar belirteçleri ile rabdomyoliz tanısı konuldu. Görüntülemelerle intrakraniyal patolojiyi dışlandı ve Doppler ultrasonografi ile vasküler tıkanıklık dışlandı. Tedaviye rağmen, hasta palyatif bir ortamda uzun süreli bakıma ihtiyaç duydu.

Sonuç: Urtica dioica geleneksel olarak tıbbi özellikleriyle bilinse de tahriş edici etkileri dermal maruziyet sonrasında ciddi sistemik rahatsızlıklara yol açabilir. Bulgular, yaygın olarak karşılaşılan bir bitkiden kaynaklanan yaşamı tehdit edici sonuçlar potansiyelini vurgulayarak, bu tür vakalarda farkındalık ve acil müdahale ihtiyacını vurgulamaktadır. Klinisyenler benzer sunumlara sahip hastaları yönetirken bu riskleri göz önünde bulundurmalıdır.

References

  • Abi Sleiman M, Younes M, Hajj R, et al. Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials. Int J Mol Sci. 2024;25(13):7501. doi:10.3390/ijms25137501
  • Halder S, Sharma A. A review on Urtica dioica L. World J Pharm Pharm Sci. 2017;6(10).
  • Zeytin AT, Ergün N, Çevik AA, Özçelik H. Altered mental status and delayed serious allergic reaction after drinking the boiled water of nettle (Urtica dioica). Turk J Emerg Med. 2008;8(3):136-138.
  • Cummings AJ, Olsen M. Mechanism of Action of Stinging Nettles. Wilderness Environ Med. 2011;22(2):136-139. doi:10.1016/j.wem.2011.01.001
  • Devkota HP, Paudel KR, Khanal S, et al. Stinging Nettle (Urtica dioica L.): Nutritional Composition, Bioactive Compounds, and Food Functional Properties. Molecules. 2022;27(16). doi:10.3390/molecules27165219
  • Đurović S, Kojić I, Radić D, et al. Chemical Constituents of Stinging Nettle (Urtica dioica L.): AComprehensive Review on Phenolic and Polyphenolic Compounds and Their Bioactivity. Int J Mol Sci. 2024;25(6):3430. doi:10.3390/ijms25063430
  • Northall F. Vegetation, vegetables, vesicles: plants and skin. Emergency Nurse. 2003;11(3):18-23. doi:10.7748/en2003.06.11.3.18.c7656
  • Kolovou G, Cokkinos P, Bilianou H, Kolovou V, Katsiki N, Mavrogeni S. Non-traumatic and non-drug-induced rhabdomyolysis. Archives of Medical Science – Atherosclerotic Diseases. 2019;4(1). doi:10.5114/amsad.2019.90152
  • Batur A. Travmatik Rabdomiyoliz (CRUSH Yaralanması) Yönetimi. Anatolian Journal of Emergency Medicine. 2023;6(1):41-46. doi:10.54996/anatolianjem.1252372.
There are 9 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Case Report
Authors

Hasan Özden 0009-0000-8005-0638

Ali Kemal Erenler 0000-0002-2101-8504

İlter Ağaçkıran 0000-0003-4859-2220

Merve Ağaçkıran 0000-0002-9986-7370

Early Pub Date December 30, 2024
Publication Date December 30, 2024
Submission Date December 9, 2024
Acceptance Date December 20, 2024
Published in Issue Year 2024 Volume: 7 Issue: 4

Cite

AMA Özden H, Erenler AK, Ağaçkıran İ, Ağaçkıran M. A Rare Case of Impaired Consciousness, Compartment Syndrome and Rhabdomyolisis Following Local Dermal Exposure to Stinging Nettles (Urtica dioica). Anatolian J Emerg Med. December 2024;7(4):178-181. doi:10.54996/anatolianjem.1598496