Current Approaches in the Diagnosis and Treatment of Sepsis in Pediatric Patients

Year 2024, Volume: 7 Issue: 4, 182 - 189, 30.12.2024

Emel Ekşi Alp , Dilara Türkan

https://doi.org/10.54996/anatolianjem.1604382

Abstract

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In pediatric patients, sepsis manifests with distinct characteristics due to age-specific differences and comorbidities. This review examines recent updates in the pediatric sepsis diagnostic criteria and management strategies. The Phoenix Sepsis Score (PSS) represents a novel approach developed to identify sepsis and septic shock in pediatric patients. The key aspects of management encompass early diagnosis, hemodynamic support, antimicrobial therapy, and individualized treatment. Advancements at the molecular level have facilitated tailored therapies, while multidisciplinary approaches have contributed to improved clinical outcomes.

Keywords

Pediatric sepsis, Phoenix Sepsis Score, emergency medicine

Çocuk Hastalarda Sepsis Tanı ve Tedavisinde Güncel Yaklaşımlar

Abstract

Sepsis, enfeksiyona karşı düzensiz konak yanıtıyla oluşan ve yaşamı tehdit eden organ disfonksiyonu olarak tanımlanır. Çocuklarda sepsis, yaşa özgü farklılıklar ve komorbiditeler nedeniyle erişkinlerden farklı bir tablo çizer. Bu derlemede, pediatrik sepsis tanı kriterlerindeki güncellemeler ve yönetim stratejileri ele alınmıştır. Phoenix Sepsis Skoru (PSS), pediatrik hastalarda sepsis ve septik şokun tanımlanması için geliştirilmiş yeni bir yaklaşımdır. Erken tanı, hemodinamik destek, antimikrobiyal tedavi ve bireyselleştirilmiş tedavi gibi başlıca unsurlar sepsis yönetiminde önem taşır. Moleküler düzeydeki gelişmeler, tedavinin kişiye özel olarak uyarlanmasını sağlarken, multidisipliner yaklaşımlar klinik sonuçların iyileştirilmesine katkı sunmaktadır.

Keywords

Pediatrik sepsis, Phoenix Sepsis Skoru, acil servis

Ethical Statement

Yazarlar araştırma ve yayın etiğine uyduklarını beyan eder.

Supporting Institution

Çalışma yapılırken veya yazının hazırlanasında herhangi bir finansal destek alınmamıştır.

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