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Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method

Year 2019, Volume: 13 Issue: 1, 21 - 26, 29.04.2019

Abstract

Objectives: Bone age (BA) is used in age determination for a number of medico-legal reasons. One of the most commonly used radiographic methods in BA assessment is to compare hand-wrist radiographs with a standard reference. In this
study, Greulich-Pyle (GP) method was used to determine the bone maturation values of a population of children and adolescents living in the city of Erzurum, Turkey.

Methods: Hand and wrist radiographs of 507 individuals (243 boys and 264 girls) aged between 7–19 years were evaluated
and the BA was estimated by a radiologist using the GP method. Difference between estimated BA and chronological age (CA)
was analyzed.

Results: In boys, except for the ages of 12,13 and 17 years, BA was significantly lower than the chronological age. In girls, BA
was significantly lower than CA at 7, 8, 18 and 19 years of age, but not statistically different in the other ages.

Conclusion: According to the GP atlas, it is suggested that many factors including high altitude, cold climate, environment,
nutrition, genetics, ethnics and socio-economic diversities might cause differences between BA and CA. Our results obtained
in this study suggest that this method can guide the determination of bone age in children living in Erzurum, Turkey.
However, in certain age groups for both genders, the GP method significantly underestimated skeletal age. 

References

  • 1. Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford (CA): Stanford University Press; 1959. p. 50–250. 2. The Turkish Civil Code Law No. 4721. Official Gazette, Date: 8.12.2001, Article 11. 3. Gardner E, Gray DJ, O’Rahilly R. Anatomy. Philadelphia (PA): WB Saunders; 1969. pp. 279–83. 4. Levine E. The contributions of the carpal bones and the epiphyseal centres of the hand to the assessment of skeletal maturity. Hum Biol 1972;44:317–27. 5. Marshall WA, Ashcroft MT, Bryan G. Skeletal maturation of the hand and wrist in Jamaican children. Hum Biol 1970;42:419–35. 6. Jiménez-Castellanos J, Carmona A, Catalina-Herrera CJ, Viñuales M. Skeletal maturation of wrist and hand ossification centers in normal Spanish boys and girls: a study using the Greulich-Pyle method. Acta Anat 1996;155:206–11. 7. Lejarraga H, Guimarey L, Orazi V. Skeletal maturity of the hand and wrist of healthy Argentinian children aged 4–12 years, assessed by the TWII method. Ann Hum Biol 1997;24:257–61. 8. Zhen OY, Baolin L. Skeletal maturity of the hand and wrist in Chinese school children in Harbin assessed by the TW2 method. Ann Hum Biol 1986;13:183–7. 9. Melsen B, Wenzel A, Miletic T, Andreasen J. Dental and skeletal maturity in adoptive children: assessments at arrival and after one year in the admitting country. Journal Ann Hum Biol 1986;13:153– 9. 10. Ashizawa K, Asami T, Anzo M, Matsuo N, Matsuoka H, Murata M, Ohtsuki F, Satoh M, Tanaka T, Tatara H, Tsukagoshi K. Standard RUS skeletal maturation of Tokyo children. Ann Hum Biol 1996;23: 457–69. 11. Pawson IG. The effects of high altitudes on child growth and development. Int J Biometeorol 1977;21:171–8. 12. Wells JC. Environmental temperature and human growth in early life. J Theor Biol 2000;204:299–305. 13. Tanner JM, Whitehouse RH, Cameron N, Marshall WA. Assessment of skeletal maturity and prediction of adult height (TW2 method). London: Academic Press; 1975. p. 99. 14. Ahmed ML, Warner JT. TW2 and TW3 bone ages: time to change? Arch Dis Child 2007;92:371–2. 15. Neyzi O. Ertu¤rul C. Koç L. Child health and diseases. [Book in Turkish] Istanbul: Istanbul Faculty of Medicine Foundation & Bayda Publications; 1984. p. 21–4. 16. Takai S, Akiyoshi T. Skeletal maturity of Japanese children in Western Kyushu. Am J Phys Anthropol 1983;62:199–204. 17. Takai S. Smoothed skeletal maturity curve of Japanese children by Tanner-Whitehouse 2 (TW2) method and its application. Kaibogaku Zasshi 1990;65:436–47. 18. Kimura K. Skeletal maturity of the hand and wrist in Japanese children in Sapporo by the TW2 method. Ann Hum Biol 1977:449– 53. 19. Helm S. Skeletal maturity in Danish school children assessed by the TW2 method. Am J Phys Anthrop 1979;51:345–52. 20. Kimura K. Skeletal maturity of the hand and wrist in Japanese children by the TW2 method. Ann Hum Biol 1977;4:353–6. 21. Waldmann E, Baber FM, Field CE, Billewicz WZ, Thomson AM. Skeletal maturation of Hong Kong Chinese children in the first five years of life. Ann Hum Biol 1977;4:343–52. 22. Bloom W. A textbook of histology. Philadelphia (PA): WB Saunders; 1968. p. 144–69 23. Büken B, Safak AA, Yazici B, Büken E, Mayda AS. Is the assessment of bone age by the Greulich-Pyle method reliable at forensic age estimation for Turkish children? Forensic Sci Int 2007;173:146–53. 24. Magnússon TE. Skeletal maturation of the hand in Iceland. Acta Odontol Scand 1979;37:21–8. 25. Katzman DK, Bachrach LK, Carter DR, Marcus R. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab 1991;73:1332–9. 26. Murata M. Characteristics of pubertal growth in Japanese children from the standpoint of skeletal growth. Acta Paediatr Jpn 1992;34:236–42. 27. Liu B, Wang D, Wang Z. Comparison of skeletal development between rural and urban school-age children. [Article in Chinese] Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1994;16:165–9. 28. Jahari AB, Saco-Pollitt C, Husaini MA, Pollitt E. Effects of an energy and micronutrient supplement on motor development and motor activity in undernourished children in Indonesia. Eur J Clin Nutr 2000;54:60–8. 29. Öztürk F, Karatafl OH, Mutaf HI, Babacan H. Bone age assessment: comparison of children from two different regions with the Greulich–Pyle method in Turkey. Australian Journal of Forensic Sciences 2016;48:1–10. 30. Taranger J, Karlberg J, Bruning B, Engström I. Standard deviation score charts of skeletal maturity and its velocity in Swedish children assessed by the Tanner-Whitehouse method (TW2-20). Ann Hum Biol 1987;14:357–65.
Year 2019, Volume: 13 Issue: 1, 21 - 26, 29.04.2019

Abstract

References

  • 1. Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford (CA): Stanford University Press; 1959. p. 50–250. 2. The Turkish Civil Code Law No. 4721. Official Gazette, Date: 8.12.2001, Article 11. 3. Gardner E, Gray DJ, O’Rahilly R. Anatomy. Philadelphia (PA): WB Saunders; 1969. pp. 279–83. 4. Levine E. The contributions of the carpal bones and the epiphyseal centres of the hand to the assessment of skeletal maturity. Hum Biol 1972;44:317–27. 5. Marshall WA, Ashcroft MT, Bryan G. Skeletal maturation of the hand and wrist in Jamaican children. Hum Biol 1970;42:419–35. 6. Jiménez-Castellanos J, Carmona A, Catalina-Herrera CJ, Viñuales M. Skeletal maturation of wrist and hand ossification centers in normal Spanish boys and girls: a study using the Greulich-Pyle method. Acta Anat 1996;155:206–11. 7. Lejarraga H, Guimarey L, Orazi V. Skeletal maturity of the hand and wrist of healthy Argentinian children aged 4–12 years, assessed by the TWII method. Ann Hum Biol 1997;24:257–61. 8. Zhen OY, Baolin L. Skeletal maturity of the hand and wrist in Chinese school children in Harbin assessed by the TW2 method. Ann Hum Biol 1986;13:183–7. 9. Melsen B, Wenzel A, Miletic T, Andreasen J. Dental and skeletal maturity in adoptive children: assessments at arrival and after one year in the admitting country. Journal Ann Hum Biol 1986;13:153– 9. 10. Ashizawa K, Asami T, Anzo M, Matsuo N, Matsuoka H, Murata M, Ohtsuki F, Satoh M, Tanaka T, Tatara H, Tsukagoshi K. Standard RUS skeletal maturation of Tokyo children. Ann Hum Biol 1996;23: 457–69. 11. Pawson IG. The effects of high altitudes on child growth and development. Int J Biometeorol 1977;21:171–8. 12. Wells JC. Environmental temperature and human growth in early life. J Theor Biol 2000;204:299–305. 13. Tanner JM, Whitehouse RH, Cameron N, Marshall WA. Assessment of skeletal maturity and prediction of adult height (TW2 method). London: Academic Press; 1975. p. 99. 14. Ahmed ML, Warner JT. TW2 and TW3 bone ages: time to change? Arch Dis Child 2007;92:371–2. 15. Neyzi O. Ertu¤rul C. Koç L. Child health and diseases. [Book in Turkish] Istanbul: Istanbul Faculty of Medicine Foundation & Bayda Publications; 1984. p. 21–4. 16. Takai S, Akiyoshi T. Skeletal maturity of Japanese children in Western Kyushu. Am J Phys Anthropol 1983;62:199–204. 17. Takai S. Smoothed skeletal maturity curve of Japanese children by Tanner-Whitehouse 2 (TW2) method and its application. Kaibogaku Zasshi 1990;65:436–47. 18. Kimura K. Skeletal maturity of the hand and wrist in Japanese children in Sapporo by the TW2 method. Ann Hum Biol 1977:449– 53. 19. Helm S. Skeletal maturity in Danish school children assessed by the TW2 method. Am J Phys Anthrop 1979;51:345–52. 20. Kimura K. Skeletal maturity of the hand and wrist in Japanese children by the TW2 method. Ann Hum Biol 1977;4:353–6. 21. Waldmann E, Baber FM, Field CE, Billewicz WZ, Thomson AM. Skeletal maturation of Hong Kong Chinese children in the first five years of life. Ann Hum Biol 1977;4:343–52. 22. Bloom W. A textbook of histology. Philadelphia (PA): WB Saunders; 1968. p. 144–69 23. Büken B, Safak AA, Yazici B, Büken E, Mayda AS. Is the assessment of bone age by the Greulich-Pyle method reliable at forensic age estimation for Turkish children? Forensic Sci Int 2007;173:146–53. 24. Magnússon TE. Skeletal maturation of the hand in Iceland. Acta Odontol Scand 1979;37:21–8. 25. Katzman DK, Bachrach LK, Carter DR, Marcus R. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab 1991;73:1332–9. 26. Murata M. Characteristics of pubertal growth in Japanese children from the standpoint of skeletal growth. Acta Paediatr Jpn 1992;34:236–42. 27. Liu B, Wang D, Wang Z. Comparison of skeletal development between rural and urban school-age children. [Article in Chinese] Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1994;16:165–9. 28. Jahari AB, Saco-Pollitt C, Husaini MA, Pollitt E. Effects of an energy and micronutrient supplement on motor development and motor activity in undernourished children in Indonesia. Eur J Clin Nutr 2000;54:60–8. 29. Öztürk F, Karatafl OH, Mutaf HI, Babacan H. Bone age assessment: comparison of children from two different regions with the Greulich–Pyle method in Turkey. Australian Journal of Forensic Sciences 2016;48:1–10. 30. Taranger J, Karlberg J, Bruning B, Engström I. Standard deviation score charts of skeletal maturity and its velocity in Swedish children assessed by the Tanner-Whitehouse method (TW2-20). Ann Hum Biol 1987;14:357–65.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Articles
Authors

Cengiz Öztürk This is me

Mete Özdikici This is me

Samih Diyarbakır This is me

Publication Date April 29, 2019
Published in Issue Year 2019 Volume: 13 Issue: 1

Cite

APA Öztürk, C., Özdikici, M., & Diyarbakır, S. (2019). Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method. Anatomy, 13(1), 21-26.
AMA Öztürk C, Özdikici M, Diyarbakır S. Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method. Anatomy. April 2019;13(1):21-26.
Chicago Öztürk, Cengiz, Mete Özdikici, and Samih Diyarbakır. “Radiographic Evaluation of Bone Maturations in Children and Adolescents Living in Erzurum Using Greulich-Pyle Method”. Anatomy 13, no. 1 (April 2019): 21-26.
EndNote Öztürk C, Özdikici M, Diyarbakır S (April 1, 2019) Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method. Anatomy 13 1 21–26.
IEEE C. Öztürk, M. Özdikici, and S. Diyarbakır, “Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method”, Anatomy, vol. 13, no. 1, pp. 21–26, 2019.
ISNAD Öztürk, Cengiz et al. “Radiographic Evaluation of Bone Maturations in Children and Adolescents Living in Erzurum Using Greulich-Pyle Method”. Anatomy 13/1 (April 2019), 21-26.
JAMA Öztürk C, Özdikici M, Diyarbakır S. Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method. Anatomy. 2019;13:21–26.
MLA Öztürk, Cengiz et al. “Radiographic Evaluation of Bone Maturations in Children and Adolescents Living in Erzurum Using Greulich-Pyle Method”. Anatomy, vol. 13, no. 1, 2019, pp. 21-26.
Vancouver Öztürk C, Özdikici M, Diyarbakır S. Radiographic evaluation of bone maturations in children and adolescents living in Erzurum using Greulich-Pyle method. Anatomy. 2019;13(1):21-6.

Anatomy is the official journal of Turkish Society of Anatomy and Clinical Anatomy (TSACA).