Case Report
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Year 2020, Volume: 14 Issue: 3, 216 - 219, 30.12.2020

Stanislav Philipov Ivan Maslarski , Mariya Koleva-ıvanova Dorian Dikov

Abstract

References

  • Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ , Brown N, Reese J, Baker CVH. Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol 2018;444:S308–S324.
  • Albrecht S, Zbieranowski I. Incidental glomus coccygeum: when a normal structure looks like a tumor. Am J Surg Pathol 1990;14:922– 4.
  • Bisceglia M, Bisceglia S, Ciampi C, Panniello G, Galliani C. Glomus coccygeum: a review. Pathologica 2018;110:287–93.
  • Rahemtullah A, Szyfelbein K, Zembowicz A. Glomus coccygeum: report of a case and review of the literature. Am J Dermatopathol 2005;27:497–9.
  • Santos LD, Chow C, Kennerson AR. Glomus coccygeum may mimic glomus tumour. Pathology 2002;34:339–43.
  • Gatalica Z, Wang L, Lucio ET, Miettinen M. Glomus coccygeum in surgical pathology specimens: small troublemaker. Arch Pathol Lab Med 1999;123:905–8.
  • Miettinen M, McCue PA, Sarlomo-Rikala M, Bernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF. Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors. Am J Surg Pathol 2015;39:826–35.
  • Conti A, Maestroni GJ, Cosentino M, Frigo GM, Lecchini S, Marino F, Bombelli R, Ferrari M, Brivio F, Roselli MG, Lissoni P. Evidence for a neuroimmunomodulatory and a hematopoietic role of the Luschka’s coccygeal body (3). Neuro Endocrinol Lett 2000;21:391– 403.
  • Maggiani F, Kashima T, Simon J, Athanasou NA. Immunophenotypic analysis of glomus coccygeum associated with coccygodynia. Skeletal Radiol 2011;40:1455–9.
  • Karamchandani JR, O Nielsen T, van de Rijn M, West RB. Sox10 and S100 in the diagnosis of soft-tissue neoplasms. Appl Immunohistochem Mol Morphol 2012;5:445–50.
  • Davis J, Petterson M, Newell J, Lauwers GY, Royce T, Demeure MJ. Micrometastatic gastric glomus tumour confirmed by next-generation sequencing. Histopathology 2018;72:351–4.

Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression

Year 2020, Volume: 14 Issue: 3, 216 - 219, 30.12.2020

Stanislav Philipov Ivan Maslarski , Mariya Koleva-ıvanova Dorian Dikov

Abstract

We report two new cases of glomus coccygeum in pilonidal sinus excision specimens. The positive expression of glomus coccygeum cells for SOX10 is used for the first time. SOX10 is a useful immunohistochemical marker for identifying this microanatomical structure, confirming the diagnosis and may help the differential diagnosis. The glomus coccygeum cells are probably neural crest-derived from multipotent Schwann cell precursors.

Keywords

glomous coccygeum pilonidal sinus SOX10 vestigial structure sacral area

References

  • Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ , Brown N, Reese J, Baker CVH. Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol 2018;444:S308–S324.
  • Albrecht S, Zbieranowski I. Incidental glomus coccygeum: when a normal structure looks like a tumor. Am J Surg Pathol 1990;14:922– 4.
  • Bisceglia M, Bisceglia S, Ciampi C, Panniello G, Galliani C. Glomus coccygeum: a review. Pathologica 2018;110:287–93.
  • Rahemtullah A, Szyfelbein K, Zembowicz A. Glomus coccygeum: report of a case and review of the literature. Am J Dermatopathol 2005;27:497–9.
  • Santos LD, Chow C, Kennerson AR. Glomus coccygeum may mimic glomus tumour. Pathology 2002;34:339–43.
  • Gatalica Z, Wang L, Lucio ET, Miettinen M. Glomus coccygeum in surgical pathology specimens: small troublemaker. Arch Pathol Lab Med 1999;123:905–8.
  • Miettinen M, McCue PA, Sarlomo-Rikala M, Bernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF. Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors. Am J Surg Pathol 2015;39:826–35.
  • Conti A, Maestroni GJ, Cosentino M, Frigo GM, Lecchini S, Marino F, Bombelli R, Ferrari M, Brivio F, Roselli MG, Lissoni P. Evidence for a neuroimmunomodulatory and a hematopoietic role of the Luschka’s coccygeal body (3). Neuro Endocrinol Lett 2000;21:391– 403.
  • Maggiani F, Kashima T, Simon J, Athanasou NA. Immunophenotypic analysis of glomus coccygeum associated with coccygodynia. Skeletal Radiol 2011;40:1455–9.
  • Karamchandani JR, O Nielsen T, van de Rijn M, West RB. Sox10 and S100 in the diagnosis of soft-tissue neoplasms. Appl Immunohistochem Mol Morphol 2012;5:445–50.
  • Davis J, Petterson M, Newell J, Lauwers GY, Royce T, Demeure MJ. Micrometastatic gastric glomus tumour confirmed by next-generation sequencing. Histopathology 2018;72:351–4.
There are 11 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Reports
Authors

Stanislav Philipov This is me 0000-0003-2467-7561

Ivan Maslarski 0000-0001-7126-9232

Mariya Koleva-ıvanova This is me 0000-0002-2014-7435

Dorian Dikov This is me 0000-0002-2404-7538

Publication Date December 30, 2020
Published in Issue Year 2020 Volume: 14 Issue: 3

Cite

APA Philipov, S., Maslarski, I., Koleva-ıvanova, M., Dikov, D. (2020). Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression. Anatomy, 14(3), 216-219.
AMA Philipov S, Maslarski I, Koleva-ıvanova M, Dikov D. Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression. Anatomy. December 2020;14(3):216-219.
Chicago Philipov, Stanislav, Ivan Maslarski, Mariya Koleva-ıvanova, and Dorian Dikov. “Glomus Coccygeum in Pilonidal Sinus Surgical Specimens: Report of Two Rare Cases With Special Reference to SOX10 Expression”. Anatomy 14, no. 3 (December 2020): 216-19.
EndNote Philipov S, Maslarski I, Koleva-ıvanova M, Dikov D (December 1, 2020) Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression. Anatomy 14 3 216–219.
IEEE S. Philipov, I. Maslarski, M. Koleva-ıvanova, and D. Dikov, “Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression”, Anatomy, vol. 14, no. 3, pp. 216–219, 2020.
ISNAD Philipov, Stanislav et al. “Glomus Coccygeum in Pilonidal Sinus Surgical Specimens: Report of Two Rare Cases With Special Reference to SOX10 Expression”. Anatomy 14/3 (December 2020), 216-219.
JAMA Philipov S, Maslarski I, Koleva-ıvanova M, Dikov D. Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression. Anatomy. 2020;14:216–219.
MLA Philipov, Stanislav et al. “Glomus Coccygeum in Pilonidal Sinus Surgical Specimens: Report of Two Rare Cases With Special Reference to SOX10 Expression”. Anatomy, vol. 14, no. 3, 2020, pp. 216-9.
Vancouver Philipov S, Maslarski I, Koleva-ıvanova M, Dikov D. Glomus coccygeum in pilonidal sinus surgical specimens: report of two rare cases with special reference to SOX10 expression. Anatomy. 2020;14(3):216-9.
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Anatomy is the official journal of Turkish Society of Anatomy and Clinical Anatomy (TSACA).