Case Report
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Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report

Year 2024, Volume: 18 Issue: 3, 111 - 113, 30.12.2024

Abstract

The twelfth cranial nerve, known as the hypoglossal nerve, is a somatomotor nerve. Functionally, it innervates the intrinsic muscles of the tongue and all extrinsic tongue muscles except the palatoglossus. Anatomically, the hypoglossal nerve exits the cranium via the hypoglossal canal. This case report describes a variation identified during routine dissection of two adult cadavers in the dissection laboratory of the Karabük University Faculty of Medicine, Department of Anatomy. During the standard dissection procedure, the cranial cavity was first exposed, and the brain tissue was removed. Subsequent examination revealed that, in one cadaver, the hypoglossal nerve on the left side exited the cranium through two separate small foramina instead of the typical hypoglossal canal. A review of the literature indicated that reports on this anatomical variation are scarce. This case report aims to contribute valuable insights to the field of anatomy and provide critical information for clinicians performing surgical procedures in this region.

Ethical Statement

The authors confirm that they have complied with ethical guidelines for cadaveric studies.

Thanks

The authors would like to express their endless gratitude to the body donors and their families who have made great contributions to the science of anatomy.

References

  • Nayak SB. Unilateral, double hypoglossal nerves leaving the cranial cavity through two hypoglossal foramina: a case report. Neuroanatomy 2008;7:6–7.
  • Erzurumlu R, Şengül G, Ulupınar E. Nöroanatomi. Ankara: Güneş Tıp Kitapevleri; 2023. p. 259–60.
  • Yasin A. Her yönüyle anatomi. Istanbul: Istanbul Tıp Kitabevi; 2019. p. 534–6.
  • Arıncı A, Elhan A. Anatomi. 2 cilt. İstanbul: Güneş Kitapevi; 2006. p. 155.
  • Nikumbh RD, Nikumbh DB, Karambelkar RR, Shewale AD. Morphological study of hypoglossal canal and its anatomical variation. International Journal of Health Sciences and Research 2013; 3:54–8.
  • Kachlík D, Varga I, Báča V, Musil V. Variant anatomy and its terminology. Medicina (Kaunas) 2020;56:713.
  • Islam S, Walton G, Howe D. Aberrant anatomy of the hypoglossal nerve. J Laryngol Otol 2012;126:538–40.
  • Bergman R, Thompson S, Afifi A, Saadeh F. Compendium of the human anatomic variation. Text, atlas and world literature. Baltimore (MD): Urban and Schwarzenberg; 1988. p. 200.
  • Demir BT, Patat D. Morphological and morphometric analysis of hypoglossal canal and its importance in cranial base surgery: a skull study. Konuralp Medical Journal 2023;15:136–43.
  • Bhuller A, Sanudo J, Choi D, Abrahams P. Intracranial course and relations of the hypoglossal nerve: an anatomic study. Surg Radiol Anat 1998;20:109–12.
  • Wysocki J, Kobryń H, Bubrowski M, Kwiatkowski J, Reymond J, Skarżyńska B. The morphology of the hypoglossal canal and its size in relation to skull capacity in man and other mammal species. Folia Morphol (Warsz) 2004;63:11–7.
  • Carolineberry A, Berry RJ. Epigenetic variation in the human cranium. J Anat 1967;101:361.
  • Zaidi S, Gupta R, Usman N. A study of hypoglossal canal in north indian crania. Journal of Anatomical Society of India 2011;60:224–6.
  • De Francisco M, Lemos J, Liberti E, Adamo J, Jacomo A, Matson E. Anatomical variations in the hypoglossal canal. Rev Odontol Univ Sao Paulo 1990;4:38–42.
  • Muthukumar N, Swaminathan R, Venkatesh G, Bhanumathy S. A morphometric analysis of the foramen magnum region as it relates to the transcondylar approach. Acta Neurochir (Wien) 2005;147:889–95.
Year 2024, Volume: 18 Issue: 3, 111 - 113, 30.12.2024

Abstract

References

  • Nayak SB. Unilateral, double hypoglossal nerves leaving the cranial cavity through two hypoglossal foramina: a case report. Neuroanatomy 2008;7:6–7.
  • Erzurumlu R, Şengül G, Ulupınar E. Nöroanatomi. Ankara: Güneş Tıp Kitapevleri; 2023. p. 259–60.
  • Yasin A. Her yönüyle anatomi. Istanbul: Istanbul Tıp Kitabevi; 2019. p. 534–6.
  • Arıncı A, Elhan A. Anatomi. 2 cilt. İstanbul: Güneş Kitapevi; 2006. p. 155.
  • Nikumbh RD, Nikumbh DB, Karambelkar RR, Shewale AD. Morphological study of hypoglossal canal and its anatomical variation. International Journal of Health Sciences and Research 2013; 3:54–8.
  • Kachlík D, Varga I, Báča V, Musil V. Variant anatomy and its terminology. Medicina (Kaunas) 2020;56:713.
  • Islam S, Walton G, Howe D. Aberrant anatomy of the hypoglossal nerve. J Laryngol Otol 2012;126:538–40.
  • Bergman R, Thompson S, Afifi A, Saadeh F. Compendium of the human anatomic variation. Text, atlas and world literature. Baltimore (MD): Urban and Schwarzenberg; 1988. p. 200.
  • Demir BT, Patat D. Morphological and morphometric analysis of hypoglossal canal and its importance in cranial base surgery: a skull study. Konuralp Medical Journal 2023;15:136–43.
  • Bhuller A, Sanudo J, Choi D, Abrahams P. Intracranial course and relations of the hypoglossal nerve: an anatomic study. Surg Radiol Anat 1998;20:109–12.
  • Wysocki J, Kobryń H, Bubrowski M, Kwiatkowski J, Reymond J, Skarżyńska B. The morphology of the hypoglossal canal and its size in relation to skull capacity in man and other mammal species. Folia Morphol (Warsz) 2004;63:11–7.
  • Carolineberry A, Berry RJ. Epigenetic variation in the human cranium. J Anat 1967;101:361.
  • Zaidi S, Gupta R, Usman N. A study of hypoglossal canal in north indian crania. Journal of Anatomical Society of India 2011;60:224–6.
  • De Francisco M, Lemos J, Liberti E, Adamo J, Jacomo A, Matson E. Anatomical variations in the hypoglossal canal. Rev Odontol Univ Sao Paulo 1990;4:38–42.
  • Muthukumar N, Swaminathan R, Venkatesh G, Bhanumathy S. A morphometric analysis of the foramen magnum region as it relates to the transcondylar approach. Acta Neurochir (Wien) 2005;147:889–95.
There are 15 citations in total.

Details

Primary Language English
Subjects Central Nervous System, Neurosciences (Other)
Journal Section Case Reports
Authors

Yusuf Seçgin 0000-0002-0118-6711

Nesibe Yılmaz 0000-0002-5527-8507

Publication Date December 30, 2024
Submission Date September 4, 2024
Acceptance Date December 12, 2024
Published in Issue Year 2024 Volume: 18 Issue: 3

Cite

APA Seçgin, Y., & Yılmaz, N. (2024). Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report. Anatomy, 18(3), 111-113.
AMA Seçgin Y, Yılmaz N. Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report. Anatomy. December 2024;18(3):111-113.
Chicago Seçgin, Yusuf, and Nesibe Yılmaz. “Unilateral Separation of the Hypoglossal Nerve from the Cranial Cavity through Two Hypoglossal Foramina: Case Report”. Anatomy 18, no. 3 (December 2024): 111-13.
EndNote Seçgin Y, Yılmaz N (December 1, 2024) Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report. Anatomy 18 3 111–113.
IEEE Y. Seçgin and N. Yılmaz, “Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report”, Anatomy, vol. 18, no. 3, pp. 111–113, 2024.
ISNAD Seçgin, Yusuf - Yılmaz, Nesibe. “Unilateral Separation of the Hypoglossal Nerve from the Cranial Cavity through Two Hypoglossal Foramina: Case Report”. Anatomy 18/3 (December 2024), 111-113.
JAMA Seçgin Y, Yılmaz N. Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report. Anatomy. 2024;18:111–113.
MLA Seçgin, Yusuf and Nesibe Yılmaz. “Unilateral Separation of the Hypoglossal Nerve from the Cranial Cavity through Two Hypoglossal Foramina: Case Report”. Anatomy, vol. 18, no. 3, 2024, pp. 111-3.
Vancouver Seçgin Y, Yılmaz N. Unilateral separation of the hypoglossal nerve from the cranial cavity through two hypoglossal foramina: case report. Anatomy. 2024;18(3):111-3.

Anatomy is the official journal of Turkish Society of Anatomy and Clinical Anatomy (TSACA).