SYNTHESIS OF MEMBRANE STRUCTURES CONTAINING NANOCOMPOSITES FOR IMMUNOGLOBULIN G (IgG) ADSORPTION

Year 2024, Volume: 3 Issue: 1, 178 - 190, 25.04.2024

Hilal Özçelik , Yasemin Subaşı , Mirza Kibaroğlu , Esra Yaşar , Timuçin Güner , Kaan Tiktaş , Sinan Akgöl

Abstract

The discovery of markers of many diseases, such as cancer, inflammation, diabetes, cardiovascular diseases and other autoimmune diseases, can be made through the characterization of serum protein or peptide. Proteomics, the large-scale analysis of proteins, will make a major contribution to our understanding of gene function in the post-genomic era. Proteomics is the quantitative and physical mapping of total proteins in a particular cell line, tissue, body fluids, or organism.
In our study, it is aimed to adsorption of antibodies from solutions Accordingly, GO-HEMA membranes were synthesized by photopolymerization method, followed by scanning electron microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). During IgG binding to GO-HEMA membranes, pH, temperature, concentration and time parameters were examined.

Keywords

Proteomics, antibody removal, composite materials, membrane systems, graphene

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