Investigation of Brucella Seroprevalence and Risk Factors in Patients Admitting to a University Hospital

Year 2020, Volume: 34 Issue: 2, 65 - 70, 31.08.2020

Muammer Osman Köksal , Mehmet Akif Durmuş , Hayati Beka , Ali Ağaçfidan

https://doi.org/10.5222/ankem.2020.065

Abstract

Brucellosis is a bacterial infectious disease that can be transmitted by consumption of unpasteurized milk and dairy products and through direct contact of secretions from infected animals with the skin with impaired integrity. It remains a significant public health issue in our country. The aim of this study was to investigate Brucella seroprevalence and the risk factors associated with brucellosis in Istanbul. Sera from 467 patients who were sent to medical microbiology laboratories with suspicion of brucellosis from various polyclinics or hospital services of Istanbul Medical Faculty between December 2018 and December 2019 were included in this study. Brucellacapt test (Vircell, Spain) were used to diagnose the infection. Seropositivity was observed in a total of 18 patients (3,85 %). Seropositivity was significantly higher in male patients (p<0,05). Our study contributes to existing data on this infection. We believe that our results may also be important for raising awareness of risk groups.

Keywords

brucellosis, public health, seroprevalence

Ethical Statement

The study was approved by the Ethics Committee of Istanbul University, Istanbul Faculty of Medicine (Reference number: 955/2020).

Bir Üniversite Hastanesine Başvuran Hastalarda Brucella Seroprevalansı ve Risk Faktörlerinin Araştırılması

Abstract

Bruselloz, pastörize edilmemiş süt ve süt ürünlerinin tüketimi ve enfekte hayvanların sekresyonlarının bütünlüğü bozulmuş cilt ile direkt teması ile bulaşabilen bakteriyel bir enfeksiyon hastalığıdır. Ülkemizde önemli bir halk sağlığı sorunu olmaya devam etmektedir. Çalışmamızda, İstanbul’da Brucella seroprevalansının ve bruselloz ile ilişkili risk faktörlerinin incelenmesi amaçlanmıştır. Bu çalışmaya Aralık 2018-Aralık 2019 tarihleri arasında İstanbul Üniversitesi, İstanbul Tıp Fakültesi’ne bağlı çeşitli poliklinik veya servislerinden, bruselloz şüphesi ile tıbbi mikrobiyoloji laboratuvarlarına gönderilen 467 hasta serumu dahil edilmiştir. Enfeksiyonun tanısında Brucellacapt testi (Vircell, İspanya) kullanılmıştır. Toplam 18 hastada (% 3,85) pozitiflik gözlemlenmiştir. Seropozitiflik, erkek hastalarda anlamlı derecede yüksek bulunmuştur (p<0,05). Çalışmamız bu enfeksiyon ile ilgili var olan verilere katkıda bulunmaktadır. Çalışma sonuçlarımızın, risk gruplarının bilinçlendirilmesi için de önemli olabileceğini düşünmekteyiz.

Keywords

bruselloz, halk sağlığı, seroprevalans

Ethical Statement

Çalışma İstanbul Universitesi, İstanbul Tıp Fakültesi Etik kurulu tarafından onaylanmıştır (Referans numarası: 955/2020).

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