Ailesel Herediter Gingival Fibromatozis: Nadir Bir Olgu Sunumu

Year 2013, Volume: 2 Issue: 2, 1 - 4, 01.10.2013

Serkan Dündar Mustafa Özay Uslu Vesile Elif Toy Abubekir Eltas

Abstract

Herediter gingivofibromatosis çeşitli derecelerde diş etinin büyüme gösterdiği nadir görülen genetik bir olgudur. Genellikle tek başına bir rahatsızlık olarak görülebildiği gibi multisistemik rahatsızlıkların bir bulgusu olarak da görülebilmektedir. Şiddetli vakalarda tedavi şeçeneği büyümüş dokuların rezektif cerrahi yöntemle uzaklaştırılması iken diş eti büyümeleri tekrar görülebilir. Bu vakada 28 yaşında sağlıklı bir hastada ailesel olarak görülen alt ve üst çenede şiddetli diş eti büyümeleri ile karakterize herediter gingivofibromatosis vakası sunulmuştur

Keywords

Herediter gingivofibromatosis, diş eti büyümesi, gingivektomi

Familial Hereditary Gingival Fibromatosis: A Rare Case Report

Abstract

Hereditary gingival fibromatosis is a rare genetic condition characterized by varying degrees of growth attached gingiva. It usually develops as an isolated disorder but can be one feature of a multi systemic syndrome. In severe cases resective surgery of the fibromatosis excess tissue is the treatment available however, recurrence is a common feature. In this case a 28-year-old healty male is reported who presented a familial hereditary gingival fibromatosis, characterized with severe gingival overgrowth, involving the maxillary and mandibular arches

Keywords

Hereditary gingival fibromatosis, gingival enlargement, gingivectomy

References

• Coletta R, Graner E: Hereditary gingival fibromatosis: a systematic review. J Periodontol 2006; 77: 753-764.
• Şahin S, Saygun NI. Hereditary Gingival Fibromatosis. Journal of Gazi University Faculty of Dentistry 2008; 25(2) : 45-50.
• Kelekis-Cholakis A, Wiltshire WA, Birek C. Treatment and Long-term Follow-up of a Patient with Hereditary Gingival Fibromatosis:A Case Report. J Can Dent Assoc 2002; 68(5):290-294.
• Baptista IP. Hereditary gingival fibromatosis: a case report. J Clin Periodontol 2002; 29: 871–874
• Bayar GR, Özkan A, Şençimen M, Altuğ HA, Gülses A, Günhan Ö. Idiopathic gingival fibromatosis: Case report. Gülhane Medical Journal 2011; 53: 294-296.
• Odessey EA, Cohn AB, Casper F, Schechter LS. Hereditary Gingival Fibromatosis. Aggressive 2-Stage Surgical Resection in Lieu of Traditional Therapy. Ann Plast Surg 2006;57: 557–560.
• Wynne SE, Aldred MJ, Bartold MP. Hereditary gingival fibromatosis associated with hearing loss and supernumerary teeth a new syndrome. J Periodontol 1995; 66(1):75-79.
• Hakkı SS. Pathology of periodontal diseases. In: Çağlayan G (eds). Periodontology. Ankara: Hacettepe University Press, 2010:93-94.
• Casavecchia P, Uzel MI, Kantarcı A, Hastürk H, Dibart S, Hart CT, Trackman PC, Van Dyke TE. Hereditary gingival fibromatosis associated with generalized aggressive periodontitis: A case report. J Periodontol 2004; 75: 770-778.
• Martelli JH, Lemos DP, Silva CO, Graner E, Coletta RD: Hereditary gingival fibromatosis: Report of a five- generation family using cellular proliferation analysis. J Periodontol 2005;76: 2299-2305.
• Tipton DA, Woodard III ES, Baber MA, Dabbous MK. Role of the c-myc proto-oncogene in the proliferation of hereditary gingival fibromatosis fibroblasts. J Periodontol 2004;75: 360-369.
• Almedia JP, Coletta RD, Silva SD, Agostini M, Vargas PA, Bozzo L, Graner E. Proliferation of fibroblasts cultured from normal gingiva and hereditary gingival fibromatosis is dependent on fatty acid synthase activity. J Periodontol 2005;76:272-278.