Şam keçilerinde gebelik süresince bazı kan biyokimyasal parametreleri ve minerallerindeki değişikliklerin değerlendirilmesi

Yıl 2024, Cilt: 3 Sayı: 2, 40 - 49

Serkan İrfan Köse , Ece Koldaş Ürer , Ayşe Merve Köse

Öz

Keçilerin sağlığı, mineral ve biyokimyasal profillerinin incelenmesiyle doğru bir şekilde tahmin edilebilir. Çevre, yönetim teknikleri, cinsiyet, yaş, ırk, mevsim ve üreme sürecinin fizyolojik evreleri dahil olmak üzere çok sayıda faktör bu profiller üzerinde etkili olabilir. Bu nedenle, bu çalışmada gebelik öncesi, gebelik ve doğum sonrası dönemlerde Şam keçilerinde metabolik profildeki değişiklikler araştırıldı. Bu amaçla çalışmada, östrus senkronizasyonu ile gebelik elde edilen multipar keçilerden oluşan bir sürüden seçilen, 3-6 yaş arası, ortalama 40-60 kg ağırlığında, tek fötus taşıyan 12 Şam keçisi kullanıldı. Keçilerden juguler ven’den senkronizasyondan önce, gebelik sırasında [55. (erken gebelik), 95. (orta gebelik) ve 135. (geç gebelik) gün] ve doğumdan sonra olmak üzere beş kez kan örnekleri alındı. Kan örneklerinde AST(SGOT) U/L, GGT U/L, BUN mg/dL, Glukoz mg/dL, Kolesterol mg/dL, Toplam Protein g/dL, Albümin/dL, Globulin g/dL, Albümin/Globulin oranı, Kalsiyum g/dL, Magnezyum g/dL ve Fosfor g/dL konsantrasyonları metabolik profilin değerlendirilmesi amacıyla ölçüldü. AST düzeylerinin senkronizasyon öncesi hariç diğer tüm dönemlerde (erken, orta, geç gebelik ve doğum sonrası) daha yüksek olduğu görüldü. Senkronizasyondan sonra serum GGT düzeylerinde belirgin bir azalma, gebelik ve doğum sonrası dönemleri de kapsayan kademeli bir artış tespit edildi. Kan üre azotu düzeyleri tüm gebelik dönemlerinde farklı düzeylerde saptandı, en yüksek düzey orta gebelik döneminde tespit edildi. Bu dönemde diğer gebelik dönemlerinden farklı olarak hem glukoz hem de kolesterol düzeyi daha yüksek izlendi. Geç gebelik döneminde kan proteini konsantrasyonunun belirgin olarak azaldığı izlendi. Serum kalsiyum düzeyleri erken gebelikte senkronizasyon öncesine kıyasla artarken, gebelik boyunca kalsiyum düzeyleri arasındaki fark istatistiksel olarak anlamlı bir şekilde değişmedi. Serum magnezyum düzeyleri gebelik boyunca düzenli bir artış gösterdi. Serum fosfor düzeylerinin orta gebelikte daha düşük olduğu bulundu. Çalışma sonuçları, kolesterol, fosfor, albümin ve AST'nin gebelik ortasında belirgin şekilde değişen parametreler olduğunu, kan üre azotu, glikoz, kalsiyum ve magnezyumun ise doğum sonrası dönemde daha fazla değişen parametreler olduğunu gösterdi. Buna göre, gebe Şam keçilerinin metabolik profilinin gebelik ortasından doğum sonrası döneme kadar izlenmesinin olası metabolik sorunları önlemede yararlı olabileceği kanaatine varıldı.

Anahtar Kelimeler

Gebelik, Metabolik Profil, Şam Keçileri

Evaluation of the alterations in some blood biochemical parameters and minerals during gestation period in Damascus goats

Öz

The health of goats can be accurately predicted by examining their mineral and biochemical profiles. Numerous factors, including the environment, management techniques, gender, age, breed, season, and physiological phases of reproduction, might have an impact on these profiles. Hence, this study investigated the alterations in the metabolic profile of Damascus goats before pregnancy, during gestational, and postpartum period. For this purpose, twelve Damascus goats, bearing single fetuses, aged 3-6 years with an average weight of 40-60 kg, selected from a herd of multiparous goats in which pregnancy was obtained by estrus synchronization, were used in the study. The blood samples of that goats were collected five times from the jugular vein: before synchronization (BS), during pregnancy [55th (early pregnancy; EP), 95th (mid-pregnancy; MP), and 135th (late pregnancy; LP) days], and after parturition (PP). In blood samples, AST(SGOT) U/L, GGT U/L, BUN mg/dL, Glucose mg/dL, Cholesterol mg/dL, Total Protein g/dL, Albumin/dL, Globulin g/dL, Albumin to Globulin ratio, Calcium g/dL, Magnesium g/dL and Phosphorus g/dL concentrations were measured the evaluation of the metabolic profile. AST levels were found to be higher in all other periods (early, mid, and late pregnancy and postpartum) except before synchronization. A notable decrease in serum GGT levels after synchronization and a gradual increase, including during the gestation and postpartum periods, were detected. The different levels of blood urea nitrogen were determined in all pregnancy periods, with the highest level being detected in the MP period. In the MP period, contrary to other gestation periods, both glucose and cholesterol levels were observed to be higher. The concentration of blood proteins was observed to be markedly diminished during the LP period. Serum Ca levels increased in EP compared to BS, while the difference in Ca levels throughout pregnancy did not change statistically significantly. Serum magnesium levels exhibited a regular increase throughout the course of pregnancy. Serum P levels were found to be lower during MP. The study results indicated that cholesterol, phosphorus, albumin, and AST are the most noticeably altered parameters in the mid-pregnancy period, while blood urea nitrogen, glucose, calcium, and magnesium are the parameters more significantly altered in the postpartum period. Accordingly, it was concluded that monitoring the metabolic profile of pregnant Damascus goats from mid-pregnancy to the postpartum period may be useful in preventing possible metabolic problems.

Anahtar Kelimeler

Damascus Goats, Metabolic Profile, Pregnancy

Kaynakça

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