The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation

Volume: 33 Number: 3 September 11, 2006
  • Nail Derelioglu
  • Semiha Noyan
  • Bartu Sarisozen
  • Oner Gedikoglu
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The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation

Abstract

The effects of Hyaluronic acid, Vitamin A and E on tendon healing and adhesion formation were studied in an experimental model. For this purpose achilles tendons of rats were injured by blunt trauma. In the treatment groups vitamin E was injected by I.M. way, Vitamin A was added to diet and hyaluronan was injected into the tendon sheat. Control group had no treatment. On the 30th day, objects were killed, achilles tendons were removed as a whole and used as achilles tendon functional unit. Adhesion formation were evaluated macroscopically. Biomechanical strength of the tendon was assessed by linear tensiometer and tendon healing was evaluated histologically. Hyaluronan was effective on preventing adhesion formation while vitamin A and E had no effect. There was no difference between the biomechanical strength of tendons in treatment groups and control group. Vitamin E had a significant role on subsiding the inflammatory response during healing and normal tendon structure was obtained more rapidly comparing to the other groups.

Keywords

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Nail Derelioglu This is me

Semiha Noyan This is me

Bartu Sarisozen This is me

Oner Gedikoglu This is me

Publication Date

September 11, 2006

Submission Date

March 6, 2014

Acceptance Date

-

Published in Issue

Year 1999 Volume: 33 Number: 3

DOI

https://doi.org/10.3944/aott.v33i3.2341

IZ

https://izlik.org/JA98GR95PT

Cite

RIS / Bibtex
APA
Derelioglu, N., Noyan, S., Sarisozen, B., & Gedikoglu, O. (2006). The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation. Acta Orthopaedica et Traumatologica Turcica, 33(3), 221-224. https://doi.org/10.3944/aott.v33i3.2341
AMA
1.Derelioglu N, Noyan S, Sarisozen B, Gedikoglu O. The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation. Acta Orthopaedica et Traumatologica Turcica. 2006;33(3):221-224. doi:10.3944/aott.v33i3.2341
Chicago
Derelioglu, Nail, Semiha Noyan, Bartu Sarisozen, and Oner Gedikoglu. 2006. “The Effects of Hyaluronic Acid, Vitamin A and E on Tendon Healing and Adhesion Formation”. Acta Orthopaedica et Traumatologica Turcica 33 (3): 221-24. https://doi.org/10.3944/aott.v33i3.2341.
EndNote
Derelioglu N, Noyan S, Sarisozen B, Gedikoglu O (September 1, 2006) The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation. Acta Orthopaedica et Traumatologica Turcica 33 3 221–224.
IEEE
[1]N. Derelioglu, S. Noyan, B. Sarisozen, and O. Gedikoglu, “The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation”, Acta Orthopaedica et Traumatologica Turcica, vol. 33, no. 3, pp. 221–224, Sept. 2006, doi: 10.3944/aott.v33i3.2341.
ISNAD
Derelioglu, Nail - Noyan, Semiha - Sarisozen, Bartu - Gedikoglu, Oner. “The Effects of Hyaluronic Acid, Vitamin A and E on Tendon Healing and Adhesion Formation”. Acta Orthopaedica et Traumatologica Turcica 33/3 (September 1, 2006): 221-224. https://doi.org/10.3944/aott.v33i3.2341.
JAMA
1.Derelioglu N, Noyan S, Sarisozen B, Gedikoglu O. The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation. Acta Orthopaedica et Traumatologica Turcica. 2006;33:221–224.
MLA
Derelioglu, Nail, et al. “The Effects of Hyaluronic Acid, Vitamin A and E on Tendon Healing and Adhesion Formation”. Acta Orthopaedica et Traumatologica Turcica, vol. 33, no. 3, Sept. 2006, pp. 221-4, doi:10.3944/aott.v33i3.2341.
Vancouver
1.Nail Derelioglu, Semiha Noyan, Bartu Sarisozen, Oner Gedikoglu. The effects of hyaluronic acid, vitamin A and E on tendon healing and adhesion formation. Acta Orthopaedica et Traumatologica Turcica. 2006 Sep. 1;33(3):221-4. doi:10.3944/aott.v33i3.2341